Effect of Preoperational Mechanical Ventilation on Short-Term Postoperative Outcomes in Patients with Severe Tetralogy of Fallot

Dong, Miao; Ma, Zhiyong; Wang, Jian-tang; Chai, Shoudong; Tang, Ping; Wang, Lexin

doi:10.1016/j.hlc.2012.06.021

Cited by 2 publications

(1 citation statement)

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“…The diagnosis is made clinically and by exclusion of other diseases that cause similar symptoms and signs, most notably sepsis, anaphylaxis, and angioedema [1,2]. Most of the reported cases of SCLS were in adults [1], although there have been several reports on SCLS in young children following operations for congenital heart diseases [4,5]. SCLS in infants has not been reported.…”

Section: Introductionmentioning

confidence: 99%

Systemic capillary leak syndrome due to systemic inflammatory response syndrome in infants: a report on 31 patients

Yang

et al. 2014

Open Medicine

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AbstractThe aim of this study was to describe the clinical features, management strategies and outcomes of 31 infants with systemic capillary leak syndrome (SCLS) secondary to sepsis or systemic inflammatory response syndrome. There were 23 boys and 8 girls, with an average age 9.6 ± 2.1 days (range, 3.1 to 20 days). The primary disease was pneumonia in 11 patients and sepsis in other 20. Within 72 hrs of admission, all had progressive skin and mucosal edema, septic shock, respiratory distress, oliguria and severe hypoalbuminemia (10–20g/L). Other complications were pulmonary edema or hemorrhage, disseminated intravascular coagulopathy, heart failure, renal or liver dysfunction. All patients were treated with mechanical ventilation with a mean mechanical ventilation time of 19.7± 3.5 days. Intravenous hydroxyethyl starch was also applied at an early stage for 4–12 days, together with broad spectrum antibiotics, plasma and albumin infusion. Twenty one patients (67.0%) were discharged from the neonatal intensive care unit after a median stay of 29 days, and 7 died (37.0%) in the hospital. During a 6.3-month follow-up, 4 patients had hydrocephalus and another 4 had muscle spasm or rigidity in the lower-limbs. We conclude that SCLS is a serious complication of neonatal sepsis with a high rate of in-hospital mortality and post-discharge disability.

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