Effect of pre-injection of Shenfu injection on the hemodynamics of elderly patients with hypertension undergoing laparoscopic radical resection of colorectal cancer

Abstract

To investigate the effect of pre-injection Shenfu injection on the hemodynamics of radical resection of colorectal cancer in elderly patients with hypertension. The candidates were randomly divided into control group (receiving pre-injection of sodium chloride injection) and research group (receiveing pre-injection of Shenfu injection) before anesthesia induction. The perioperative hemodynamic changes and use of vasoactive drugs were compared. Mean arterial pressure (MAP), diastolic blood pressure (DBP) and systolic blood pressure (SBP) values in the research group were lower than those in the control group at the time of tracheal tube extraction (P < 0.05). The use rate of antihypertensive drugs in the research group was lower than those in the control group (P < 0.05). Pre-injection of Shenfu in elderly hypertensive patients had no influence on anesthesia effect and it can reduce the volatility of hemodynamic parameters, decrease the use of vasoactive drugs.