Abstract:Background
Polypharmacy, defined as the concurrent use of over six drugs, is common in the treatment of heart failure (HF); however, unpredictable drug interactions with bepridil may occur. In this study, we have elucidated the influence of polypharmacy on plasma bepridil concentrations in patients with HF.
Methods
We conducted a multicenter retrospective study involving 359 adult patients with HF who received oral bepridil. Because QT prolongation… Show more
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