Effect of plasma exposure on silver nanoparticles embedded in polyvinyl alcohol

Pragatheeswaran, A.; Kareem, T. Abdul; Kaliani, A. Anu

doi:10.1088/1742-6596/208/1/012109

Cited by 7 publications

(6 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The XRD analysis led to confirmation of the silver phase, with characteristic strong Bragg reflections corresponding to (111), (200), (220), and (311) planes of fcc silver (JCPDS No.4-0783). 27,28 It indicates the silver nanoparticles were incorporated too within the PLGA particles.…”

Section: Resultsmentioning

confidence: 99%

Composite PLGA/AgNpPGA/AscH Nanospheres with Combined Osteoinductive, Antioxidative, and Antimicrobial Activities

Stevanović

Uskoković

Filipović

et al. 2013

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

The global rise in the resistance of pathogens to conventional antibiotics has created an intensive search for alternative materials with antimicrobial properties. This study is performed with an intention to investigate the combined effects of poly(L-glutamic acid)-capped silver nanoparticles (AgNpPGA) and ascorbic acid (AscH) encapsulated within freeze-dried poly(lactide-co-glycolide) (PLGA) nanospheres to obtain a nanomaterial with simultaneous osteoinductive, antioxidative, and prolonged antimicrobial properties. The influence of PLGA/AgNpPGA/AscH particles on (i) viability and super-oxide production of human umbilical vein endothelial cells in vitro, (ii) morphology and expression of osteogenic markers in osteoblastic MC3T3-E1 cells in vitro, and (iii) antimicrobial activity against a Gram-positive bacterium, methicillin-resistant Staphylococcus aureus, and a Gram-negative bacterium, Escherichia coli, was investigated. PLGA/AgNpPGA/AscH nanoparticles showed a superior and extended antibacterial activity against both types of bacteria. The nanoparticles appeared to be capable of delivering ascorbate to the cells, which was evidenced by the significant decrease in the level of superoxides in human umbilical vein endothelial cells and which could have a therapeutic potential in preventing oxidative stress. PLGA/AgNpPGA/AscH nanoparticles had a positive effect on MC3T3-E1 osteoblastic cells in vitro, promoting: (i) an intimate contact with the cells and preservation of their healthy morphologies; (ii) unreduced cell viability; and (iii) multiple-fold upregulation of two osteogenic markers: osteocalcin and type I procollagen. It is concluded that PLGA/AgNpPGA/AscH nanospheres present a promising new material for the treatment of infections and use in wound dressings and other prophylactic applications.

show abstract

Section: Resultsmentioning

confidence: 99%

Composite PLGA/AgNpPGA/AscH Nanospheres with Combined Osteoinductive, Antioxidative, and Antimicrobial Activities

Stevanović

Uskoković

Filipović

et al. 2013

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

show abstract

“…The UV-Vis absorption spectra of all core AuNPs ( Figure 1 a–c) showed an LSPR in the 522–552 nm region depending on their shape, average size, and size distribution [ 13 , 15 , 16 , 17 ]. It is well known that the number of the LSPR peaks decreases as the symmetry of the AuNP increases [ 2 , 15 , 16 , 17 ]. The presence of a single, relatively symmetrical LSPR peak at the indicated wavelengths is indicative of spherical AuNPs [ 2 , 13 , 15 , 16 , 17 ].…”

Section: Resultsmentioning

confidence: 99%

“…It is well known that the number of the LSPR peaks decreases as the symmetry of the AuNP increases [ 2 , 15 , 16 , 17 ]. The presence of a single, relatively symmetrical LSPR peak at the indicated wavelengths is indicative of spherical AuNPs [ 2 , 13 , 15 , 16 , 17 ]. The LSPR peak of the borohydride-citrate-capped AuNPs (552 nm) appeared at a higher wavelength position when compared to the citrate-capped AuNPs (523 nm) and the SDS-capped AuNPs (522 nm).…”

Section: Resultsmentioning

confidence: 99%

Experimental and Theoretical Screening of Core Gold Nanoparticles and Their Binding Mechanism to an Anticancer Drug, 2-Thiouracil

Lorenzana-Vázquez,

Adams,

Reyna

et al. 2023

Molecules

View full text Add to dashboard Cite

This study demonstrated the capability of two readily available optical spectroscopy tools, namely UV-Vis absorption spectrophotometry and Raman/surface-enhanced Raman spectroscopy, to select in a rapid and noninvasive manner the most homogenous gold nanoparticle (AuNP) models and to identify their chemical binding mechanism to 2-thiouracil (2-TU). 2-TU is an anticancer drug of great promise in the antiproliferative and photothermal therapies of cancer. The citrate-capped AuNPs emerged as the most stable as well as time- and cost-effective AuNP model out of the three widely used colloidal nanocores (citrate-, borohydride-citrate-, and sodium dodecyl sulfate (SDS)-capped AuNPs) that were examined. 2-TU chemically attached to the relatively monodispersed AuNPs via a chemisorption mechanism. The 2-TU-AuNPs complex formed through the covalent bonding of the S atom of 2-TU to the nanosurface in a vertical orientation. The spectroscopic results were then confirmed with the help of density functional theory (DFT) calculations and other physicochemical characterization tools for nanomaterials such as transmission electron microscopy (TEM), dynamic light scattering (DLS), and zeta potential. Overall, the purified 2-TU-AuNPs were found to be spherical, had an average diameter of 25 ± 2 nm, a narrow size distribution (1–30 nm), a sharp localized surface plasmon resonance (LSPR) peak at 525 nm, and a negative surface charge (−14 mV).

show abstract

“…Typical SAED patterns of AgNp and AgNpPGA nanoparticles in Fig. 8 reveal the coexistence of Ag nanoparticles with cubic and hexagonal crystal structures [46, 47]. Figure 9 shows a high-resolution TEM image of a typically multiply twined silver nano-particle.…”

Section: Resultsmentioning

confidence: 99%

A new, simple, green, and one-pot four-component synthesis of bare and poly(α,γ,l-glutamic acid)-capped silver nanoparticles

et al. 2011

View full text Add to dashboard Cite

A simple and green chemical method has been developed to synthesize stable bare and capped silver nanoparticles based on the reduction of silver ions by glucose and capping by poly(α,γ,L-glutamic acid) (PGA). The use of ammonia during synthesis was avoided. PGA has had a dual role in the synthesis and was used as a capping agent to make the silver nanoparticle more biocompatible and to protect the nanoparticles from agglomerating in the liquid medium. The synthesized PGA-capped silver nanoparticles in the size range 5–45 nm were stable over long periods of time, without signs of precipitation. Morphological examination has shown that the silver nanoparticles had a nearly spherical, multiply twinned structure. The effects of the reaction temperature and the reaction time during the synthesis were investigated too. The biocompatibility of the PGA-capped silver nano-particles is discussed in terms of in vitro toxicity with human intestinal Caco-2 cells. The samples were characterized by UV–Visible spectroscopy, field emission scanning electron microscopy, transmission electron microscopy, and zeta potential measurements.

show abstract

Effect of plasma exposure on silver nanoparticles embedded in polyvinyl alcohol

Cited by 7 publications

References 14 publications

Composite PLGA/AgNpPGA/AscH Nanospheres with Combined Osteoinductive, Antioxidative, and Antimicrobial Activities

Composite PLGA/AgNpPGA/AscH Nanospheres with Combined Osteoinductive, Antioxidative, and Antimicrobial Activities

Experimental and Theoretical Screening of Core Gold Nanoparticles and Their Binding Mechanism to an Anticancer Drug, 2-Thiouracil

A new, simple, green, and one-pot four-component synthesis of bare and poly(α,γ,l-glutamic acid)-capped silver nanoparticles

Contact Info

Product

Resources

About