Effect of Piperine on Ir/IRS -1/AKT Signaling Molecules in High-Fat Diet and Sucrose-Fed Type 2 Diabetic Rat
Abstract:Diabetes is a chronic disease that occurs either when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces. Type 2 diabetics are insulin resistant. Insulin acts on AKT signaling molecules which then act on GLUT 4 which increases glucose uptake and glucose in the case of diabetic patients this pathway is absent to indicate that the pathway piperine is used. This study aims to evaluate the effect of piperine on Ir/ IRS-1/AKT signalling molecules in high-fat… Show more
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