Effect of physical activity on asthma control in schoolchildren

Santos, Ana Paula dos; Strassburger, Márcio Júnior; Roncada, Cristian; Stein, Renato T.; Pitrez, Paulo Márcio; Strassburger, Simone Zeni

doi:10.31744/einstein_journal/2020ao4936

Cited by 9 publications

(15 citation statements)

References 30 publications

(60 reference statements)

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“…Two hypotheses can explain our findings. First, both groups had controlled asthma, and this hypothesis is supported by previous studies showing that subjects with controlled asthma experience fewer asthma symptoms and therefore have a higher PAL than do subjects with uncontrolled asthma (28). Second, both groups exhibited a long period of sedentary behavior and a very short period of moderate-to-vigorous physical activity (MVPA).…”

Section: Discussionsupporting

confidence: 54%

Physical fitness and quality of life in adolescents with asthma and fixed airflow obstruction

Sousa

Cabral

Silva

et al. 2020

Preprint

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Asthma is a disease characterized by reversible bronchoconstriction, but some subjects develop fixed airflow obstruction (FAO). Subjects with FAO present more asthma symptoms and may have increased sedentary behavior; however, the effect of FAO on aerobic fitness and physical activity levels (PAL) remains poorly understood. Aim: To compare adolescents with asthma and FAO and adolescents with asthma without FAO in terms of aerobic fitness, PAL, muscle strength, and health-related quality of life (HRQoL). Methods: This cross-sectional study included adolescents with asthma, both sexes, and aged 12 to 18 years. They were divided into 2 groups: FAO and non-FAO groups. The adolescents were diagnosed with asthma in accordance with the Global Initiative for Asthma guidelines and underwent optimal pharmacological treatment for at least 12 months. FAO was diagnosed when FEV1/FVC ratio was below the lower limit of normal range after optimal treatment. Aerobic fitness, PAL, peripheral and respiratory muscle strength, and HRQoL were evaluated. Results: No significant differences were observed between FAO and non-FAO groups regarding the peak oxygen uptake (34.6±8.5 vs. 36.0±8.4 mLO2/min/kg), sedentary time (578±126 vs. 563±90 min/day), upper limb muscle strength (29.1±5.9 vs. 28.1±5.7 kgf), lower limb muscle strength (42.8±8.6 vs. 47.6±9.6 kgf), or HRQoL (5.1±1.3 vs. 4.7±1.4 score) (p>0.05). However, the FAO group exhibited a higher maximal expiratory pressure than did the non-FAO group (111.5±15.5 vs. 101.5±15.0 cmH2O, respectively). Conclusion: Our results suggest that FAO does not impair aerobic fitness, PAL, peripheral muscle strength, or HRQoL in adolescents with asthma. Furthermore, adolescents with asthma were physically deconditioned.

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Section: Discussionsupporting

confidence: 54%

Physical fitness and quality of life in adolescents with asthma and fixed airflow obstruction

Sousa

Cabral

Silva

et al. 2020

Preprint

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show abstract

“…5 Conflicting results have been shown for physical activity, where one study found no association with asthma control 6 whereas another study found that physically active school-children were less likely to experience loss of control. 7 A 6-month follow-up study found that reduction in forced expiratory volume in 1s (FEV1) and increased FeNO at 3 months compared with baseline increased the risk of exacerbations, whereas baseline values were not related to asthma outcomes, 8 which is in line with a 12-months follow-up study showing that baseline FeNO could not predict the loss of control. 9 However, a large cross-sectional study found that high FeNO levels were associated with asthma attacks, 10 which is supported by a 6-month primary care observational study of children aged 5-16 that identified high FeNO, practice deprivation, and previous asthma attacks as factors associated with increased risk of asthma attacks and poor asthma control.…”

Section: Introductionmentioning

confidence: 75%

Long‐term predictors of loss of asthma control in school‐aged well‐controlled children with mild to moderate asthma: A 5‐year follow‐up

Hauerslev

Garpvall

Marckmann

et al. 2021

Pediatric Pulmonology

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Background: Long-term follow-up studies establishing risk factors for loss of asthma control in well-controlled children with mild to moderate disease are lacking and are of importance for improving patient quality of life and utilization of health-care resources.Methods: Loss of asthma control was assessed in 146 school-aged children with well-controlled mild to moderate asthma from a Danish pediatric asthma outpatient clinic based on hospital admissions, emergency department (ED), or outpatient management of exacerbations, oral corticosteroid (OCS) use, or step-up of regular asthma treatment according to Global Initiative for Asthma (GINA) guidelines through a 5-year follow-up period. Risk factors included sex, ethnicity, age, body mass index (BMI), atopic comorbidity and predisposition, lung function, fractional exhaled nitric oxide (FeNO) level, exercise challenge test results, regular physical activity, GINA treatment step at baseline, and adherence to controller therapy.Results: A total of 27 (18%) children experienced 56 acute events defined by hospital admission, ED, or outpatient management. Risk of experiencing any acute event was increased with female sex (adjusted odds ratio, aOR = 2.4 (1.0-5.9), p = 0.047) and higher baseline GINA treatment step (aOR = 1.6 (1.1-2.5), p = 0.03). Furthermore, female sex (aOR = 6.1 (1.4-42.2), p = 0.01) and higher FeNO (aOR = 1.8(1.0-3.2), p = 0.04) were associated with OCS prescriptions, whereas no risk factors were identified for GINA treatment step-up during the 5-year follow-up.Conclusions: Female sex, higher FeNO, and higher baseline GINA treatment step increase the risk of long-term loss of control including acute events and OCS use in well-controlled children with mild to moderate asthma. These findings are important for primary physicians and clinicians in asthma outpatient clinics to identify seemingly well-controlled children at risk to plan more frequent follow-ups.

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“…First, both groups had controlled asthma, and this hypothesis is supported by previous studies showing that subjects with controlled asthma experience fewer asthma symptoms and therefore have a higher PAL than subjects with uncontrolled asthma. 28 Second, both groups exhibited a long period of sedentary behavior and a very short period of MVPA.…”

Section: Discussionmentioning

confidence: 95%

Physical fitness and quality of life in adolescents with asthma and fixed airflow obstruction

Sousa

Cabral

Silva

et al. 2020

Pediatric Pulmonology

View full text Add to dashboard Cite

Asthma is a disease characterized by reversible bronchoconstriction, but some subjects develop fixed airflow obstruction (FAO). Subjects with FAO present more asthma symptoms and may have increased sedentary behavior; however, the effect of FAO on aerobic fitness and physical activity levels (PAL) remains poorly understood. Aim To compare adolescents with asthma and FAO and adolescents with asthma without FAO in terms of aerobic fitness, PAL, muscle strength, and health‐related quality of life (HRQoL). Methods This cross‐sectional study included adolescents with asthma, both sexes, and aged 12–18 years. They were divided into two groups: FAO and non‐FAO groups. The adolescents were diagnosed with asthma according to the Global Initiative for Asthma guidelines and underwent optimal pharmacological treatment for at least 12 months. FAO was diagnosed when the forced expiratory volume in the first second/forced vital capacity ratio was below the lower limit of the normal range after optimal treatment. Aerobic fitness, PAL, peripheral and respiratory muscle strength, and HRQoL were evaluated. Results No significant differences were observed between FAO and non‐FAO groups regarding the peak oxygen uptake (34.6 ± 8.5 vs. 36.0 ± 8.4 mLO2/min/kg), sedentary time (578 ± 126 vs. 563 ± 90 min/day), upper limb muscle strength (29.1 ± 5.9 vs. 28.1 ± 5.7 kilograms of force [kgf]), lower limb muscle strength (42.8 ± 8.6 vs. 47.6 ± 9.6 kgf), or HRQoL (5.1 ± 1.3 vs. 4.7 ± 1.4 score; p > .05). However, the FAO group exhibited a higher maximal expiratory pressure than the non‐FAO group (111.5 ± 15.5 vs. 101.5 ± 15.0 cmH2O, respectively). Conclusion Our results suggest that FAO does not impair aerobic fitness, PAL, peripheral muscle strength, or HRQoL in adolescents with asthma. Furthermore, adolescents with asthma were physically deconditioned.

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Effect of physical activity on asthma control in schoolchildren

Cited by 9 publications

References 30 publications

Physical fitness and quality of life in adolescents with asthma and fixed airflow obstruction

Physical fitness and quality of life in adolescents with asthma and fixed airflow obstruction

Long‐term predictors of loss of asthma control in school‐aged well‐controlled children with mild to moderate asthma: A 5‐year follow‐up

Physical fitness and quality of life in adolescents with asthma and fixed airflow obstruction

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