2015
DOI: 10.1161/circimaging.114.002086
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Effect of Physical Activity on Age-Related Changes in Cardiac Function and Performance in Women

Abstract: Background— Higher levels of physical activity are associated with reduced cardiovascular mortality but its effect on age-related changes in cardiac structure and function is unknown. The present study defines the effect of daily physical activity on age-related changes in cardiac structure, function, metabolism, and performance in healthy women. Methods and Results— Sixty-three healthy women were grouped according to age (young, 20–30 ye… Show more

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Cited by 30 publications
(28 citation statements)
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“…This supports other research that indicates that peak HR is a function of age, not training [30, 57]. A difference in the response of HR following transitions from light to moderate intensity steady state cycling could have implications for O 2 delivery during SWCL exercise.…”
Section: Discussionsupporting
confidence: 87%
See 1 more Smart Citation
“…This supports other research that indicates that peak HR is a function of age, not training [30, 57]. A difference in the response of HR following transitions from light to moderate intensity steady state cycling could have implications for O 2 delivery during SWCL exercise.…”
Section: Discussionsupporting
confidence: 87%
“…These findings are in contrast to the response in typically healthy adults performing strenuous exercise, where V T plateaus once it reaches ~ 50–60% of vital capacity and further increases in V E result exclusively form increases in BF [14]. While increases in V Emax following ET have been reported in older women [53, 5557], this current study is unique in reporting the effect of short and long term ET on BF, V E and V T at peak and sub—VTP intensities. These results indicate that the higher V E of the LTT was produced from breathing larger volumes of air (V T ) rather than increases in BF.…”
Section: Discussionmentioning
confidence: 98%
“…Aging is also associated with an increased incidence and prevalence of hypertension, coronary artery disease and heart failure [2]. Chronological age, in the absence of apparent cardiac disease, leads to concentric cardiac remodelling and a decline in diastolic function, cardiac metabolism, and maximal performance [3]. These subclinical changes may lead to cardiac pathology and increased incidence of heart failure in older age [2].…”
Section: Introductionmentioning
confidence: 99%
“…The most recent data from the Women's Health Initiative study suggest that low active and sedentary women had 63% greater risk of developing cardiovascular disease than high active women [15]. A recent study in women also suggests that higher levels of habitual physical activity preserve cardiac metabolism and exercise capacity with ageing [3]. Exercise training improves cardiac autonomic regulation of the heart in both healthy people and those with cardiac disorders [16-19].…”
Section: Introductionmentioning
confidence: 99%
“…However, in older women, physical activity had no effect on eccentricity ratio E/A ratio, torsion and peak cardiac power output. These findings suggest that high-level physical activity preserves cardiac metabolism and exercise capacity with ageing but has limited effect on age-related changes in concentric remodelling, diastolic function and cardiac performance 7. Another study has shown that trained middle-aged subjects exhibit a better pattern of left ventricular energy metabolism and of diastolic function than their sedentary counterparts.…”
Section: Monitoring Myocardial Metabolic Levels: Therapeutic Implicatmentioning
confidence: 96%