Effect of phospholipid insertion on arrayed polydiacetylene biosensors

Roles of head group architecture and side chain length on colorimetric response of polydiacetylene vesicles to temperature, ethanol and pH

“…Polydiacetylene (PDA) is one of conjugated polymer that exhibits rather interesting chromic properties. It has been observed that PDA assemblies exhibit color-transition when subjected to various external stimuli including solvents (solvatochromism) [6][7][8][9], temperature (thermochromism) [10][11][12][13][14][15], pH [16][17][18][19], ions [20,21] and ligand-receptor interaction (affinochromism) [22][23][24][25][26][27][28][29][30]. This unique property renders PDAs to be utilized as an active material in various applications such as chemosensors [4,31,33], biosensors [23,[26][27][28][29][30][31][32], ion sensors [21,22,24,34], temperature sensors [14,35] and molecular switches [36].…”

Simple and highly sensitive detection of hepatotoxin microcystin-LR via colorimetric variation based on polydiacetylene vesicles

“…The immunoassay based on PDA lipids has attracted much attention with its blue-to-red color and accompanying fluorescence changes [19,35]. In the present work, the use of EDC/NHS enabled mAbs of MC-LR (anti-MC-LR)-MC8C50 to covalently link to the carboxyl groups of PDA vesicles after photopolymerization, without substantially affecting the activity of the protein [21,34].…”

Controlling the reversible thermochromism of polydiacetylene/zinc oxide nanocomposites by varying alkyl chain length

“…It has been observed that the PDA-based materials exhibit blue/purple, blue/red, or blue/orange color transitions when exposed to various external stimuli such as solvents (solvatochromism) [1][2][3][4][5][6][7][8][9], temperature (thermochromism) [10][11][12][13][14][15][16][17][18][19][20][21][22], pH [23][24][25][26][27][28][29], ions [30][31][32][33][34], biomolecules [35][36][37][38][39][40][41][42][43], and other chemicals [44,45]. Therefore, the development of sensing technologies based on this material has become rather attractive.…”