Effect of Phenylhydrazine on Delta-Aminolevulinic Acid
Dehydratase in Red Blood Cells

Abdulla, M.; Svensson, Sven

doi:10.1159/000458571

Cited by 5 publications

(1 citation statement)

References 9 publications

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“…A activity was reduced by 50-60% whereas in rats weighing > 250 g only l/4 of the lead (0.12 mmol/kg body weight) was sufficient to block the enzyme activity completely (2). This could partly be explained from the fact that younger rats have greater numbers of circulat ing reticulocytes as compared to the older ones (4). In human beings, although we find a signifi cant difference in the activity of the enzyme between newborn and adults, the difference is not as striking as that we found in the rats.…”

Section: Discussioncontrasting

confidence: 73%

Effect of Age and Diet on Delta-Aminolevulinic Acid Dehydratase in Red Blood Cells

Abdulla¹,

Hæger-Aronsen²,

Mathur³

et al. 1978

Enzyme

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ALA-D activity measured in the red blood cells of different species show considerable variations. Among the adult animals, rabbits have the highest activity and dogs, the lowest. It is a zinc-dependent enzyme and its activity is related to the age of the animals as well as the availability of zinc in the diet during the early growth period. Rats at partus have the highest ALA-D activity ever registered in any animal species and it decreases drastically during the early growth period. The red blood cells of newborn human babies have 50% higher ALA-D activity than that of adult man. When rats during their early growth period are fed on a diet containing 0.08 mmol zinc, there was a reduction in the enzyme activity whereas adult rats fed on diets containing higher and lower amounts of zinc did not show any change.

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Section: Discussioncontrasting

confidence: 73%

Effect of Age and Diet on Delta-Aminolevulinic Acid Dehydratase in Red Blood Cells

Abdulla¹,

Hæger-Aronsen²,

Mathur³

et al. 1978

Enzyme

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Alkylpyridines and Miscellaneous Organic Nitrogen Compounds

Peterson

2023

Patty's Toxicology

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This chapter provides a broad overview of topics related to the occupational use and exposure to a variety of miscellaneous nitrogen‐containing compounds. Topics addressed include chemical/physical properties, uses, exposure assessment, and toxic effects, as well as standards, regulations, and guidelines for exposure. Some of the chemicals and classes represented in this chapter include pyridine, alkylpyridines, vinylpyridines, aminopyridines, aminopicolines, pyridinethione compounds (pyrithiones), nicotine, the substituted uracils, quaternary herbicides, s ‐triazine herbicides, propazine, cyanazine, ametryn, prometryn, simazine, hexazinone, azides, and hydrazine and its derivatives.

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Alkylpyridines and Miscellaneous Organic Nitrogen Compounds

Trochimowicz¹,

Kennedy²,

Krivanek³

2012

Patty's Toxicology

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This chapter covers additional aliphatic and aromatic compounds that contain one or more nitrogen atoms in their structures and follows those discussed in Chapter 59. Pyridine and its many modified structures are described because they serve as a backbone for many industrial compounds. Several pesticides and herbicides, as well as their precursors, are included: the pyridinethiones; the substituted uracil herbicides—bromacil, lenacil, and terbacil; the quaternary herbicides–paraquat, diquat, and difenzoquat; the s ‐triazines—atrazine and propazine; and other triazine herbicides, such as ametryn, prometryne, and simazine. Simple nitrogen compounds such as azides, nitrosamines, and hydrazines are described because of important toxicological effects they can produce. Finally, two important industrial solvents, dimethylacetamide and dimethylformamide, are included because they have a long history of use and have been well studied in the occupational environment. Other than the pyridine series of chemicals and the nitroso compounds, most of the chemicals reviewed here include significant new information since the last chapter review.

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Effect of Phenylhydrazine on Delta-Aminolevulinic Acid Dehydratase in Red Blood Cells

Cited by 5 publications

References 9 publications

Effect of Age and Diet on Delta-Aminolevulinic Acid Dehydratase in Red Blood Cells

Effect of Age and Diet on Delta-Aminolevulinic Acid Dehydratase in Red Blood Cells

Alkylpyridines and Miscellaneous Organic Nitrogen Compounds

Alkylpyridines and Miscellaneous Organic Nitrogen Compounds

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