Effect of phenolic extracts of Algerian medicinal plants on the bacterial growth and adherence of Staphylococcus aureus and Bacillus cereus pathogens responsible of food poisoning.

Abstract

<p>Artemisia, one of the larger genera in the family Asteraceae, comprises from 200 to more than 500 taxa at the specific or subspecific level. Artemisia herba-alba Asso (Shih) is grown in North Africa and certain parts of Asia and Middle East. It is one of the most widely used plants in the Algerian folk medicine. The antioxidant and free radical scavenging activities of the methanolic extracted materials were tested together with their antibacterial effects against isolated bacterial strains causing food poisoning. In summary, <em>A. herba-alba</em> Asso represent a good phenolic and flavonoid content (161, 64 mg/g and 16,83mg/g, respectively) in comparison with <em>T. capitatus</em> L which represent a phenolic content of 131, 48 mg/g and 14, 96 of flavonoid content. The results shows also that the methanolic extracts of the two plants possess a strong antioxidant (DPPH, FRAP assays) and antibacterial activities, which supports their ethnopharmacological use and <em>A. herba alba</em> represent the highest values (IC 50: 2, 35 mg/ml and OD 1, 13 at 700nm). Our results show the interest of <em>A. herba-alba</em> Asso and <em>T. capitatus</em> L, among other medicinal plants, in search of new chemo-preventive agents against biofilm and planktonic growth of food spoilage pathogens. Further studies are envisaged to target the most interesting molecules responsible for these activities. It is concluded that organic extracts from <em>Artemisia herba alba</em> Asso, exert strong antioxidant activities which are related to their polyphenol contents. </p>

Synergistic antinociceptive activity of combined aqueous extracts of Artemisia campestris and Artemisia herba-alba in several acute pain models

“…Furthermore, Hispidulin (40, 5, 7-trihydroxy-6-methoxyflavone) is a flavone derivative found in both Artemisia herba-alba and campestris exhibited antioxidant, antifungal, antiinflammatory, antimutagenic, and antineoplastic properties (Patel and Patel 2017). Some very recent publications reported the antioxidant and the biological activities of the total phenolic compounds of Algerian A. herba alba and A. campestris plants using several solvents extractions: organic (methanolic, ethanolic, hexanic) or aqueous, (Dif, et al 2016, Belkacem et al 2017, Dib et al 2017, Salhi, Rahmani, et al 2017, Salhi, Saghir, et al 2017.…”