Effect of phakic collamer intraocular lens with a central hole on structural tests measurements of retinal nerve fiber layer and macula

Abstract

Aim To evaluate whether the Visian Implantable Collamer Lens with a central port (V4c ICL®; STAAR Surgical, Switzerland) affects the retinal nerve fibre layer (RNFL), macula and optic nerve head (ONH) measurements obtained by optical coherence tomography (OCT), and Heidelberg Retina Tomography (HRT). Methods This prospective study included myopic patients undergoing V4c ICL® implantation. RNFL thickness, macular thickness, ganglion cell analysis (GCA) and ONH main parameters were evaluated with RTVue OCT (Optovue Inc., USA) and Cirrus-HD OCT (Carl Zeiss Meditec, USA). ONH variables were also analysed with HRT-3 (Heidelberg Engineering, Germany). All measurements were performed before and 1 week and 12 months after the surgery. Results 31 eyes of 31 patients (mean age 30.1 ± 5.5 years) were included. Comparing with preoperative values, no significant differences in average RNFL thickness were found with RTVue, while a slight increase (4.3 µm) was detected with Cirrus-HD (85.2 ± 10.3 µm, preoperatively) at 1-week postoperatively (89.5 ± 8.3 µm; p < 0.05). Those changes were not observed at the last follow-up visit (86.6 ± 8.6 µm; p = 0.41). Cirrus-HD detected that macular thickness was slightly higher 1 week after surgery, compared with the preoperative examination (3.4% increase; p = 0.04). That difference remained stable at the 12-month postoperative visit (p = 0.01). GCA showed no changes. The ONH analysis with Cirrus-HD determined that rim area (p = 0.03) as well as disc area (p = 0.04) significantly increased. HRT-3 found no significant changes affecting those variables. Conclusions The implantation of V4c ICL® did not induce a clinically significant impact on the results of the RNFL/ONH analysis with OCT and HRT.

Retinal and Choroidal Changes Following Implantable Collamer Lens V4c Implantation in High Myopia Patients—A 1-Year Follow-Up Study

“…Interestingly, these changes were not found to be associated with SER, AL, or age. Our findings align with those of Pachon et al, who reported increased macular thickness at postoperative months 1 and 12 following ICL V4c implantation [7]. Conversely, Xu et al found no significant changes in central retinal thickness (CRT) at postoperative weeks 1, 3, and 6, as well as blood flow density of superficial and deep macular fovea [24].…”

“…Compared to prior ICL models, the V4c model has exhibited a substantial reduction in reported complications due to enhanced aqueous humor flow and preserved anterior segment physiology [4][5][6]. However, limited research exists on the impact of the V4c model on retinal and choroidal morphology, which are vital for maintaining patients' visual function [7][8][9][10][11][12].…”