Effect of Percutaneous Nephrolithotomy and Tract Dilatation Methods on Renal Function: Assessment by Quantitative Single-Photon Emission Computed Tomography of Technetium-99m–Dimercaptosuccinic Acid Uptake by the Kidneys

Ünsal, Ali; Koca, Gökhan; Reşorlu, Berkan; Bayindir, Mirze; Korkmaz, Meliha

doi:10.1089/end.2010.0008

Cited by 34 publications

(22 citation statements)

References 19 publications

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“…Unsal et al measured the effects of PNL dilatation methods on renal function in adult patients using QSPECT and DMSA uptake by the kidneys. 15 Balloons, metal, and Amplatz dilators were compared, and no difference in renal uptake was found among the three groups pre-or postoperatively. New scarring was detected in 18% of patients, and 66% of these scars were reported to be at the site of the focal defect corresponding to the access site for tract formation during PNL.…”

Section: Discussionmentioning

confidence: 96%

Effect of percutaneous nephrolithotomy on renal functions in children: assessment by quantitative SPECT of^99mTc-DMSA uptake by the kidneys

et al. 2015

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Tc-DMSA) examinations before and 3 months after surgery. Results: The mean age was 9.5 years (range, 3-16), and the mean stone size was 3.4 cm (range, 2-6.5). Of the cases, 39 (95%) were managed as being stone-free after a single session of PNL. After additional treatment procedures, 40 (97.5%) of the cases were managed as being stone-free. Of the 41 renal units, new focal cortical defects on 99m Tc-DMSA scans were seen in 4 (9.7%) patients. Total relative uptake in the treated kidneys increased from 42.3% to 44.1%. The mean creatinine level before PNL was 1.18 ± 0.45 (0.8-1.6) mg/dL compared with 1.16 (0.7-1.5) mg/dL by the end of the follow-up period (not statistically significantly different, p40.05). Conclusions: PNL in children is a safe and feasible method for the maximal clearance of stones. QSPECT of 99m Tc-DMSA confirmed that renal function is preserved or even improved after percutaneous stone removal.

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Section: Discussionmentioning

confidence: 96%

Effect of percutaneous nephrolithotomy on renal functions in children: assessment by quantitative SPECT of^99mTc-DMSA uptake by the kidneys

et al. 2015

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“…The other parameters were not significantly affected in the early term. In another similar study, Ünsal et al [13] compared percutaneous dilatation methods (balloon, Amplatz, and Alken). They found that they did not affect the renal functions at the end.…”

Section: Discussionmentioning

confidence: 99%

Assessment of the Effects of Access Count in Percutaneous Nephrolithotomy on Renal Functions by Technetium-99m-Dimercaptosuccinic Acid Scintigraphy

et al. 2013

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Objective. To determine the effects of percutaneous nephrolithotomy on renal functions by using DMSA scintigraphy while considering access counts. Material and Methods. A total of 37 patients who had undergone percutaneous nephrolithotomy were included. Preoperative DMSA scans were performed a day before the surgery, whereas postoperative scans were randomized by evaluating them before (n = 25) and after (n = 12) the 6th postoperative month. Twenty-six of 37 cases underwent percutaneous nephrolithotomy with a single access site and 11 with multiple access sites. Results. There were no significant changes of total renal functions in the whole study group (P = 0.054). In the single access group, total functions were significantly elevated (P = 0.03) In the multiple access group, while treated site functions were significantly decreased (P = 0.01), total functions did not change significantly (P = 0.42). There was an insignificant decrease in those evaluated before the 6th postoperative month (P = 0.27) and an insignificant increase in the others (P = 0.11). Conclusion. We could not find a superiority of single access over multiple accesses. There is a temporary functional loss in the treated site.

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“…[13,17,21,24] Regarding the damage to the treated kidney, PNL was again found to be unlikely to give rise to scarring in children. [23,[25][26][27][28] Dwaba et al [25] reported no scarring using dimercaptosuccinic acid (DMSA) renal scanning and stabilization or improved function with diethylene triamine pentaacetic acid (DTPA) renal scanning after PNL. To summarize, most studies demonstrate minimal scarring and insignificant loss of renal function after PNL.…”

Section: Discussionmentioning

confidence: 99%

Comparison of miniperc and conventional percutaneous nephrolithotomy in pediatric renal calculi

Tanrıverdi¹,

Kendirci²,

Aydın³

et al. 2011

Turkish Journal of Urology

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Türk Üroloji Dergisi -Turkish Journal of Urology 2011;37(2):99-104 99 Özet Amaç: Çocukluk çağı böbrek taşı hastalığında iki değişik perkütan nefrolitotomi (PNL) yönteminin (miniperk ve standart PNL) güvenliliğini ve cerrahi sonuçlarını değerlendirmek.Gereç ve yöntem: Dört yıl boyunca, iki değişik PNL prosedürü uygulanmış ortalama yaşı 10.3 (dağılım 3.5-16) olan 31 çocuk retrospektif olarak değerlendirildi. Uygulanan prosedür tipine göre hastalar iki gruba ayrıldı: Grup 1 (n=17) miniperk uygulanan olgular, Grup 2 (n=16) erişkin nefroskopu ile standart PNL yapılan olgular. İki grup demografik veriler, taş profili, başarı oranları, komplikasyon oranları ve ek prosedür gerekip gerekmediği gibi klinik ve cerrahi parametreler açısından karşılaştırıldı. Bulgular:Otuz-bir hastaya 33 primer PNL uygulandı. Miniperk uygulanan hastaların ortalama yaşı anlamlı olarak daha küçük (8.7 ve 11.8) ve akses sayısı yüksek bulundu (1.41 ve 1 port) (p<0.05). Operasyon ve floroskopi süreleri, kan transfüzyon oranları ve nefrostomi tüpünün alınma süreleri açısından ise karşılaştırılabilir sonuçlar elde edildi. Benzer şekilde hastanede yatış süresi, 3 aylık takipte taşsızlık oranları ve minör komplikasyon oranları açısından anlamlı fark saptanmadı. Her iki proserdürde de majör komplikasyon izlenmedi. Sonuçlar:Yüksek taşsızlık ve minimal komplikasyon oranı sebebi ile PNL çocukluk çağı taş hastalığında güvenli bir seçenektir. Erişkin tip aletlerin bu hasta grubunda kullanılması ile ilgili çekinceler olmasına karşın, bu çalışmanın bulguları her iki prosedürün de benzer başarı ve komplikasyon oranlarına sahip olduğunu ortaya koymaktadır.Anah tar söz cük ler: Çocuk; miniperk; perkütan nefrolitotomi; taş hastalığı. AbstractObjective: To assess the safety and surgical outcomes of two different percutaneous nephrolithotomy (PNL) procedures (miniperc versus standard PNL) in pediatric renal stone disease. Materials and methods:Over a 4-year period, a total of 31 consecutive children with a mean age of 10.3 years (range 3.5-16 years) undergoing two different PNL procedures were retrospectively evaluated. Depending on the type of procedure performed, children were divided into two groups: Group 1 (n=17) underwent a miniperc procedure, and Group 2 (n=16) underwent a standard PNL procedure with adult-size instruments. Clinical and surgical parameters including patient demographics, stone profiles, success rates in terms of stone-free status, complication rates, and the need for auxiliary procedures were compared between the groups.Results: A total of 33 primary PNL procedures performed in 31 children were evaluated. The mean age was significantly lower in children undergoing the miniperc procedure (8.7 vs. 11.8 years old), and the number of accesses made was higher (1.41 vs. 1 port) (p<0.05). In addition, operation and fluoroscopy times, rates for blood transfusions, and the mean removal time for the nephrostomy catheter, were all comparable between groups. Similarly, the mean duration of hospitalization, the stone-free rates at 3 months, and the minor...

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Effect of Percutaneous Nephrolithotomy and Tract Dilatation Methods on Renal Function: Assessment by Quantitative Single-Photon Emission Computed Tomography of Technetium-99m–Dimercaptosuccinic Acid Uptake by the Kidneys

Abstract: QSPECT of (99m)Tc-DMSA confirms that renal function is preserved or often improved after percutaneous stone removal, and nephrostomy tract dilatation methods have similar effects on renal function.

Cited by 34 publications

References 19 publications

Effect of percutaneous nephrolithotomy on renal functions in children: assessment by quantitative SPECT of^99mTc-DMSA uptake by the kidneys

Effect of percutaneous nephrolithotomy on renal functions in children: assessment by quantitative SPECT of^99mTc-DMSA uptake by the kidneys

Assessment of the Effects of Access Count in Percutaneous Nephrolithotomy on Renal Functions by Technetium-99m-Dimercaptosuccinic Acid Scintigraphy

Comparison of miniperc and conventional percutaneous nephrolithotomy in pediatric renal calculi

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Effect of Percutaneous Nephrolithotomy and Tract Dilatation Methods on Renal Function: Assessment by Quantitative Single-Photon Emission Computed Tomography of Technetium-99m–Dimercaptosuccinic Acid Uptake by the Kidneys

Abstract: QSPECT of (99m)Tc-DMSA confirms that renal function is preserved or often improved after percutaneous stone removal, and nephrostomy tract dilatation methods have similar effects on renal function.

Cited by 34 publications

References 19 publications

Effect of percutaneous nephrolithotomy on renal functions in children: assessment by quantitative SPECT of99mTc-DMSA uptake by the kidneys

Effect of percutaneous nephrolithotomy on renal functions in children: assessment by quantitative SPECT of99mTc-DMSA uptake by the kidneys

Assessment of the Effects of Access Count in Percutaneous Nephrolithotomy on Renal Functions by Technetium-99m-Dimercaptosuccinic Acid Scintigraphy

Comparison of miniperc and conventional percutaneous nephrolithotomy in pediatric renal calculi

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Effect of percutaneous nephrolithotomy on renal functions in children: assessment by quantitative SPECT of^99mTc-DMSA uptake by the kidneys

Effect of percutaneous nephrolithotomy on renal functions in children: assessment by quantitative SPECT of^99mTc-DMSA uptake by the kidneys