1970
DOI: 10.1016/0024-3205(70)90285-7
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Effect of pentobarbital on isometric contractions and parameters of active state in cat papillary muscle

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1972
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Cited by 6 publications
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“…An ino tropic agent administered to an animal under pentobarbital anesthesia might have differing effects (as observed with low doses of dopa mine in young piglets, in fig. 2), depending upon the degree of prior depression by pento barbital [11,14], We demonstrated pre viously that a low dose of isoproterenol in creased right ventricular dP/dtmax in day-old piglets anesthetized with pentobarbital, but that the inotropic response to norepinephrine required a relatively high dose at that age [ 10].…”
Section: Discussionmentioning
confidence: 94%
“…An ino tropic agent administered to an animal under pentobarbital anesthesia might have differing effects (as observed with low doses of dopa mine in young piglets, in fig. 2), depending upon the degree of prior depression by pento barbital [11,14], We demonstrated pre viously that a low dose of isoproterenol in creased right ventricular dP/dtmax in day-old piglets anesthetized with pentobarbital, but that the inotropic response to norepinephrine required a relatively high dose at that age [ 10].…”
Section: Discussionmentioning
confidence: 94%
“…The results of comparative study have been reported of volatile anesthetic agents by means of force-velocity relations in the isolated cat papillary heart muscle (Iwatsuki and Shimosato 1971), but there have been few reports of comparative study on the direct myocardial effect of intra venous anesthetic agents. In regard to barbiturates, a negative inotropic effect of pentobarbital has been well documented (Siegel and Sonnenblick 1964;Dresel et al 1970), but there have been few studies on thiamylal (Sawyer et al 1971). A direct depressive action of propanidid on the heart was suggested in the isolated guinea pig hearts and in men (Astrom et al 1970 Comparison of Thiamylal, Propanidid and CT 1341…”
mentioning
confidence: 99%