Effect of Penicillin Resistance of<i>Streptococcus pneumoniae</i>on the Presentation, Prognosis, and Treatment of Pneumococcal Endocarditis in Adults

Martínez, Estebán; Miró, José M.; Almirante, Benito; Aguado, José María; Fernández-Viladrich, P; Fernández-Guerrero, Manuel L.; Villanueva, José Luis Güell; Dronda, Fernando; Moreno‐Torrico, Alfonso; Montejo, Miguel; Llinares, Pedro; Gatell, José M.

doi:10.1086/341024

Cited by 76 publications

(49 citation statements)

References 34 publications

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“…130 Moreover, cross-resistance of pneumococci to other antimicrobial agents such as cephalosporins, macrolides, fluoroquinolones, carbapenems, and even vancomycin is increasing in frequency. In 1 multicenter study 131 with a relatively large number of patients with IE caused by IE indicates infective endocarditis; IM, intramuscular; IV, intravenous; MIC, minimum inhibitory concentration; NVE, native valve infective endocarditis; and VGS, viridans group streptococci. MIC is >0.12 to <0.5 μg/mL for penicillin.…”

Section: Endocarditis Of Prosthetic Valves or Other Prosthetic Materimentioning

confidence: 99%

Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications

Baddour¹,

Wilson²,

Bayer³

et al. 2015

Circulation

2,479

1,421

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Background— Infective endocarditis is a potentially lethal disease that has undergone major changes in both host and pathogen. The epidemiology of infective endocarditis has become more complex with today’s myriad healthcare-associated factors that predispose to infection. Moreover, changes in pathogen prevalence, in particular a more common staphylococcal origin, have affected outcomes, which have not improved despite medical and surgical advances. Methods and Results— This statement updates the 2005 iteration, both of which were developed by the American Heart Association under the auspices of the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease of the Young. It includes an evidence-based system for diagnostic and treatment recommendations used by the American College of Cardiology and the American Heart Association for treatment recommendations. Conclusions— Infective endocarditis is a complex disease, and patients with this disease generally require management by a team of physicians and allied health providers with a variety of areas of expertise. The recommendations provided in this document are intended to assist in the management of this uncommon but potentially deadly infection. The clinical variability and complexity in infective endocarditis, however, dictate that these recommendations be used to support and not supplant decisions in individual patient management.

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Section: Endocarditis Of Prosthetic Valves or Other Prosthetic Materimentioning

confidence: 99%

Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications

Baddour¹,

Wilson²,

Bayer³

et al. 2015

Circulation

2,479

1,421

View full text Add to dashboard Cite

show abstract

“…66 Moreover, cross-resistance of pneumococci to other antimicrobial agents, such as cephalosporins, macrolides, fluoroquinolones, carbapenems, and even vancomycin, is increasing in frequency. In one multicenter study 67 with a relatively large (nϭ24) number of patients with IE caused by S pneumoniae resistant to penicillin (MIC 0.1 to 4 g/mL), patients were evaluated and compared with 39 patients who were infected with penicillinsusceptible strains. Several observations were made.…”

Section: S Pneumoniae S Pyogenes and Groups B C And G Streptococcimentioning

confidence: 99%

Infective Endocarditis

Baddour¹,

Wilson²,

Bayer³

et al. 2005

Circulation

1,275

436

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Background-Despite advances in medical, surgical, and critical care interventions, infective endocarditis remains a disease that is associated with considerable morbidity and mortality. The continuing evolution of antimicrobial resistance among common pathogens that cause infective endocarditis creates additional therapeutic issues for physicians to manage in this potentially life-threatening illness. Methods and Results-This work represents the third iteration of an infective endocarditis "treatment" document developed by the American Heart Association under the auspices of the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease of the Young. It updates recommendations for diagnosis, treatment, and management of complications of infective endocarditis. A multidisciplinary committee of experts drafted this document to assist physicians in the evolving care of patients with infective endocarditis in the new millennium. This extensive document is accompanied by an executive summary that covers the key points of the diagnosis, antimicrobial therapy, and management of infective endocarditis. For the first time, an evidence-based scoring system that is used by the American College of Cardiology and the American Heart Association was applied to treatment recommendations. Tables also have been included that provide input on the use of echocardiography during diagnosis and treatment of infective endocarditis, evaluation and treatment of culture-negative endocarditis, and short-term and long-term management of patients during and after completion of antimicrobial treatment. To assist physicians who care for children, pediatric dosing was added to each treatment regimen. Conclusions-The recommendations outlined in this update should assist physicians in all aspects of patient care in the diagnosis, medical and surgical treatment, and follow-up of infective endocarditis, as well as management of associated complications. Clinical variability and complexity in infective endocarditis, however, dictate that these guidelines be used to support and not supplant physician-directed decisions in individual patient management. (Circulation. 2005; 111:e394-e433.)

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“…W ponad 30% przypadków wiąże się z zapaleniem opon mózgowo-rdzeniowych [149], co wymaga szczególnej uwagi w przypadku penicylinooporności. Leczenie w przypadku szczepów penicylinowrażliwych (MIC ≤ 0,06 mg/l) przebiega podobnie jak przy zakażeniu przez paciorkowce jamy ustnej (tab.…”

Section: Streptococcus Pneumoniae Paciorkowce B-hemolizujące (Grupy unclassified

2015 ESC Guidelines for the management of infective endocarditis

Habib¹,

Lancellotti

Antunes³

et al. 2015

Kardiol Pol

144

212

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Effect of Penicillin Resistance ofStreptococcus pneumoniaeon the Presentation, Prognosis, and Treatment of Pneumococcal Endocarditis in Adults

Cited by 76 publications

References 34 publications

Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications

Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications

Infective Endocarditis

2015 ESC Guidelines for the management of infective endocarditis

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