Effect of parenteral administration of Selenium and vitamin E on health status of mammary gland and on selected antioxidant indexes in blood of dairy cows

Abstract

This study focuses on the effect of parenteral administration of Selenium (Se) and vitamin E on concentration of Se in plasma and the activity of glutathione peroxidase (GPx) in the blood of dairy cows during peripartal period and their effect on the reduction of clinical mastitis. From a 220 individuals Holstein herd in a two-four lactation-gestation cycle the control group (C), 1 st (D1) and 2 nd (D2) experimental group were selected. Every group consisted of 15 cows in the last phase of the pregnancy. All cows were fed with the diet containing 0.1 mg of Se per kg/DM. The blood samples from vena jugularis were collected approximately 21 days before calving (control sampling), 3 days, 12 days and 21 days after calving. On the day of control sampling and 12 days before calving in D1 group, cows were injected subcutaneously in the sprescapular region with preparation Selevit inj. a.u.v. at the doses of 48.4 mg/head of Se, and 550 IU/head of α-Tocoferol (α-Toc). In D2 group, cows were injected by the same preparation only on 21 th day before calving with the same doses of Se and α-Toc.The increase in the concentration of Se in the plasma and activity GPx in blood in D1 group on the 3 rd day and 12 th day after calving were determined. Increase in plasmatic concentrations α-Toc on 3 rd day after calving and reduction of occurrence of clinical mastitis (13.3%) as compared with control group were found.

A review on Electromagnetic fields (EMFs) and the reproductive system

“…In ancient China and Egypt, it was used to treat snakebites, as a food, and for medical purposes. Fennel oil has antioxidant, antimicrobial, antispasmodic, and gastrointestinal stimulant activities (61). Allergic reactions to it occur very rarely.…”

“…Therefore, it has anti-inflammatory properties, and, due to its fibers, it prevents the transmission of toxins in the colon. In addition to fibers, fennel contains calcium, magnesium, copper, and phosphorus ions (61). Anethole is the most basic fennel compound that reduces inflammation and prevents cancer (62).…”

“…Fennel dramatically increases the number of antral, graphian, and multi-layer follicles and improves the follicugenesis process in the ovaries of mice (61). Since follicular growth is affected by endocrine hormones (FSH, LH, Prolactin and paracrine factors), the estrogenic effects of fennel may increase the number of follicles that are growing (61). Another active ingredient of fennel is diosgenin, which is essential for the synthesis of some hormones.…”

Selenium biofortified alfalfa hay fed in low quantities improves selenium status and glutathione peroxidase activity in transition dairy cows and their calves

“…Oxidative stress is associated with increased incidences of diseases (Sordillo and Mavangira, 2014), therefore, it is imperative to improve the anti-oxidative status of dairy cows. Selenium (Se) is an integral component of selenoenzymes, such as glutathione peroxidase (GPx) which play a significant role in the removal and detoxification of free radicals (Zigo et al, 2014). Thus, supplementation of Se during the peripartum can be an effective means to decrease oxidative stress (Gong and Xiao, 2018).…”

“…Selenium (Se) is an integral component of selenoenzymes, such as glutathione peroxidase (GPx) which play a significant role in the removal and detoxification of free radicals (Zigo et al ., 2014). Thus, supplementation of Se during the peripartum can be an effective means to decrease oxidative stress (Gong and Xiao, 2018).…”