Effect of parathyroid hormone (PTH), calcitonin (CT), and prostaglandin E2(PGE2) on production of matrix vesicles (MV) by primary cultures of epiphyseal growth plate chondrocytes

Chin, Jia En; Schalk, Elaine M.; Wuthier, Roy E.

doi:10.1016/8756-3282(85)90249-2

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As an alternative to growth plate cartilage, chondrocyte cultures [74,86,[109][110][111][112][113][114][115][116][117][118][119][120][121][122][123] can be used as a starting material to compare the properties of media vesicles and matrix vesicles. Chondrocytes isolated from the proliferating and hypertrophic regions of the growth plate differ significantly in their ability to release TNAP-rich matrix vesicles [105].…”

Section: Matrix Vesicles and Media Vesicles From Growth Plate Cartila...mentioning

confidence: 99%

Do Media Extracellular Vesicles and Extracellular Vesicles Bound to the Extracellular Matrix Represent Distinct Types of Vesicles?

Mebarek,

Buchet,

Pikula

et al. 2023

Biomolecules

View full text Add to dashboard Cite

Mineralization-competent cells, including hypertrophic chondrocytes, mature osteoblasts, and osteogenic-differentiated smooth muscle cells secrete media extracellular vesicles (media vesicles) and extracellular vesicles bound to the extracellular matrix (matrix vesicles). Media vesicles are purified directly from the extracellular medium. On the other hand, matrix vesicles are purified after discarding the extracellular medium and subjecting the cells embedded in the extracellular matrix or bone or cartilage tissues to an enzymatic treatment. Several pieces of experimental evidence indicated that matrix vesicles and media vesicles isolated from the same types of mineralizing cells have distinct lipid and protein composition as well as functions. These findings support the view that matrix vesicles and media vesicles released by mineralizing cells have different functions in mineralized tissues due to their location, which is anchored to the extracellular matrix versus free-floating.

show abstract

Section: Matrix Vesicles and Media Vesicles From Growth Plate Cartila...mentioning

confidence: 99%

Do Media Extracellular Vesicles and Extracellular Vesicles Bound to the Extracellular Matrix Represent Distinct Types of Vesicles?

Mebarek,

Buchet,

Pikula

et al. 2023

Biomolecules

View full text Add to dashboard Cite

show abstract

Effect of parathyroid hormone (PTH), calcitonin (CT), and prostaglandin E2(PGE2) on production of matrix vesicles (MV) by primary cultures of epiphyseal growth plate chondrocytes

Cited by 1 publication

References 0 publications

Do Media Extracellular Vesicles and Extracellular Vesicles Bound to the Extracellular Matrix Represent Distinct Types of Vesicles?

Do Media Extracellular Vesicles and Extracellular Vesicles Bound to the Extracellular Matrix Represent Distinct Types of Vesicles?

Contact Info

Product

Resources

About