2020
DOI: 10.1177/0003489420906179
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Effect of Over the Counter Ibuprofen Dosing after Sinus Surgery for Chronic Rhinosinusitis: A Prospective Cohort Pilot Study

Abstract: Introduction: Management of pain following endoscopic sinus surgery (ESS) often involves intermittent use of opioid medications. Given the current opioid crisis, many surgeons aim to minimize opioid prescriptions. However, surgeons often avoid the use of NSAIDs following ESS out of concern for increased bleeding risk. We sought to evaluate the effectiveness and safety of over the counter dosing of ibuprofen on pain and bleeding rates following ESS. Methods: Prospective cohort pilot study of patients undergoing… Show more

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Cited by 12 publications
(26 citation statements)
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“…47 Both groups took a similar amount of breakthrough opioids and the NSAID cohort reported reduced pain scores. 47 Wu et al performed a multicenter cohort study comparing mean pain VAS scores and opioid usage after ESS in patients who were given a prescription of hydrocodoneacetaminophen and recommended preferentially to take 325 mg acetaminophen vs those who were given a prescription of hydrocodone-acetaminophen and preferentially told to take 325 mg acetaminophen and 200 mg ibuprofen. The cohort that used NSAIDs were found to have decreased overall pain scores and took significantly fewer opioid pills (mean, 3.77) than the non-NSAID group (mean, 6.94; p = 0.018).…”
Section: 4mentioning
confidence: 97%
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“…47 Both groups took a similar amount of breakthrough opioids and the NSAID cohort reported reduced pain scores. 47 Wu et al performed a multicenter cohort study comparing mean pain VAS scores and opioid usage after ESS in patients who were given a prescription of hydrocodoneacetaminophen and recommended preferentially to take 325 mg acetaminophen vs those who were given a prescription of hydrocodone-acetaminophen and preferentially told to take 325 mg acetaminophen and 200 mg ibuprofen. The cohort that used NSAIDs were found to have decreased overall pain scores and took significantly fewer opioid pills (mean, 3.77) than the non-NSAID group (mean, 6.94; p = 0.018).…”
Section: 4mentioning
confidence: 97%
“…44.45 Moreover, the combination of acetaminophen and NSAIDs is effective for providing primary pain control and reducing opioid use in certain head and neck procedures. 43,44,47 The role of NSAIDs and acetaminophen in primary pain control and reducing opioid use in the immediate postoperative period has been examined in several studies (Table 3). Nguyen et al performed an RCT of pain control in postoperative head and neck surgery patients.…”
Section: 4mentioning
confidence: 99%
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“…Specifically, NSAIDs have been avoided after FESS because of the risk of epistaxis. However, NSAIDs have been shown to be safe and effective in perioperative pain management after FESS and nasal surgeries in several recent studies . There is growing evidence that NSAIDs may decrease the requirement for rescue analgesics, including opioids .…”
mentioning
confidence: 99%