Background: Premature neonates have feeding problems due to immaturity; As a result, until they acquire sufficient oral eating abilities, they require continuous enteral feeding. Interventions to enhance feeding outcomes of premature neonates and feeding outcomes is olfactory and gustatory stimulation. The study was aimed to determine the effect of olfactory and gustatory stimulations on premature neonates ' feeding progression and sniffing away feeding tube. Subjects and method: A quasiexperimental research design was used in the present study. Convenience sampling of fifty premature neonates. The study was conducted at Neonatal Intensive Care Unit of Tanta Main University Hospital which affiliated to Ministry of Higher Education and Scientific Research. Three Tools include: Characteristics of premature neonates, Feeding pattern and intolerance of premature neonates' assessment tool 2018, Growth monitoring and physiological measurement of premature neonates. The result indicated that majority of studied neonates in the study group sniffed away the feeding tube to achieve full sucking in a shorter duration than neonates within the group under control. The study concluded that premature neonates who received olfactory and gustatory stimulation had improved feeding abilities and had faster sniffing away feeding tube to reach full feeding. The study recommended that written guidelines and procedures of the NICU should adopt the olfactory and gustatory stimulations in their care.