Effect of Nonpharmacologic Pain Control During Examination for Retinopathy of Prematurity

Dolgun, Gülümser; Bozlak, Şirin

doi:10.1016/j.jogn.2017.06.008

Cited by 13 publications

(17 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…On average, infants' pain scores increased by 10 points from baseline during the examinations and remained 3 points higher than baseline scores even 2 minutes after the examinations. The severe pain (indicated by a PIPP score of >13) [18] related to the ROP examinations in our study is consistent with that found in other studies [12,13,16]. Despite the administration of topical anesthetic eye drops prior to the ROP examinations, following common clinical practice [1], preterm infants still require treatments to relieve pain during these examinations and to help them quickly recover afterwards.…”

Section: Discussionsupporting

confidence: 89%

“…The pain-relieving effects of human milk, sucrose, and distilled water (control) during ROP examinations were also compared. No differences were found in the pain score, heart rate, or oxygen saturation between the groups [13,16], although the pain scores returned to the baseline level more quickly in infants administered human milk than in those administered sucrose [16]. However, in these studies, human milk, sucrose, or distilled water was administered using an injector or a syringe without a needle, and varying (0.1~2.0 mL) amounts of solution were provided.…”

Section: Introductionmentioning

confidence: 88%

“…The pain-relieving effects of human milk, which contains natural and potentially risk-free nutrients, have also been investigated in preterm infants in response to painful procedures [11][12][13]. Human milk is believed to be a relatively safe solution as opposed to sucrose, the repeated administration of which can induce hyperglycemia in younger preterm infants [14].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Comparison of the Pain-relieving Effects of Human Milk, Sucrose, and Distilled Water during Examinations for Retinopathy of Prematurity: A Randomized Controlled Trial

Jang¹,

Lee²,

Jo³

et al. 2019

Child Health Nurs Res

View full text Add to dashboard Cite

Purpose: This study compared the pain-relieving effects of human milk, sucrose, and distilled water during examinations for retinopathy of prematurity. Methods: Forty-five preterm infants were randomly assigned to receive a pacifier dipped in one of three solutions: human milk (n=14), 24% sucrose (n=15), or distilled water (n=16), 2 minutes before an eye examination. Their pain score, pulse rate, and oxygen saturation were measured at three time points: 5 minutes before the examination, 30 seconds after speculum introduction, and 2 minutes after the examination. Results: The infants' mean gestational age and weight at birth were 33.1±2.1 weeks and 1,842±470 g, respectively. There were no between-group differences in pain relief during the eye examination. The pain score significantly increased both during (p<.001) and after the examinations (p=.003). Oxygen saturation decreased during the examinations (p<.001); however, the infants in the 24% sucrose group showed higher oxygen saturation (p=.047) during the examinations than the infants in the other groups. Conclusion: Sucking on a pacifier dipped in human milk or 24% sucrose did not reduce the pain associated with eye examinations in preterm infants. Pacifiers dipped in sucrose can be used to maintain better oxygen saturation during these examinations.

show abstract

Section: Discussionsupporting

confidence: 89%

Section: Introductionmentioning

confidence: 88%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Comparison of the Pain-relieving Effects of Human Milk, Sucrose, and Distilled Water during Examinations for Retinopathy of Prematurity: A Randomized Controlled Trial

Jang¹,

Lee²,

Jo³

et al. 2019

Child Health Nurs Res

View full text Add to dashboard Cite

show abstract

“…Pain management strategies include medications and behavioral interventions. Because of the side effects of drugs, non-drug analgesic methods such as skin contact between the mother and child, touching, breastfeeding, feeding sugar, and non-nutritive sucking are commonly used (10). At home and abroad, several studies have evaluated the analgesic effects of sucrose or breast milk during ROP screening (11).…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of Gentle Human Touch for Pain Control During Examination for Retinopathy of Pre-maturity: A Randomized Controlled Trial

et al. 2020

View full text Add to dashboard Cite

Background: Retinopathy of pre-maturity (ROP) is a disorder of the retinal blood vessels in pre-term infants with low birth weight. It is a leading cause of blindness in children. During ROP screening, the use of mydriatic drops and eyelid openers causes pain and discomfort. Pain management strategies include medications and behavioral interventions. The objectives of this study was to investigate the effects of Gentle Human Touch on pain in pre-term infants undergoing screening for ROP.Methods: In this randomized controlled trial, 82 infants in the neonatal intensive care unit at Children's Hospital of Nanjing Medical University who met the ROP screening criteria were randomly assigned to experimental and control groups using the random number table. The infants in the experimental group continuously received Gentle Human Touch during screening, while those in the control group were screened according to the routine procedure. All neonates were administered local eye anesthesia before the screening. The degree of pain was assessed using the Pre-mature Infant Pain Profile score. A double-channel near-infrared spectroscopy device was used to monitor regional cerebral oxygen saturation (rScO2), while oxygen saturation (SaO2) and heart rate were measured using pulse oximetry. The Pre-mature Infant Pain Profile score was the primary outcome, while heart rate, SaO2, and rScO2 were the secondary outcomes.Results: The gestational age, corrected gestational age, birth weight, and Apgar score at examination and the basal heart rate, SaO2, and rScO2 showed no significant intergroup differences (P > 0.05 for all). Both groups demonstrated significant decreases in SaO2 and rScO2 in response to the examination (P < 0.05 for all). During the examination, the Pre-mature Infant Pain Profile score (14.82 ± 3.22 vs. 9.29 ± 2.89, respectively; P < 0.05) was significantly higher in the control group than in the experimental group, while rScO2 (57.61 ± 3.51 vs. 54.76 ± 4.54%, respectively; P < 0.05) and SaO2 (91.89 ± 6.43 vs. 85.68 ± 8.31%; P < 0.05) were significantly higher in the experimental group than in the control group. There was no significant difference in heart rate changes between the two groups before and after the examination (182.60 ± 3.50 vs. 170.80 ± 3.50 time/min; P > 0.05).Conclusions: The findings of this study suggest that Gentle Human Touch can effectively alleviate pain during ROP screening in pre-mature infants.Clinical Trial Registration: ISRCTN10976481, Registered 06 March 2020, Retrospectively registered.

show abstract

“…Numerous studies have examined measures that might reduce the pain and stress of screening for ROP. These include pharmacological interventions such as procedural analgesia (topical anaesthetics or nitrous oxide) and nonpharmacological methods (breastmilk, sucrose, soothers and swaddling) (Dolgun & Bozlak, ; Mandel, Ali, Chen, Galic, & Levesque, ; Marsh et al., ; O'Sullivan, O'Connor, Brosnhan, McCreery, & Dempsey, ; Rush et al., ). Several studies have shown that these measures are both inadequate and ineffective (Grabska et al., ; Grunau, ; Mandel et al., ; Marsh et al., ; O'Sullivan et al., ; Rush et al., ; Samra & McGrath, ).…”

Section: Introductionmentioning

confidence: 99%

A modified developmental care bundle reduces pain and stress in preterm infants undergoing examinations for retinopathy of prematurity: A randomised controlled trial

Chuang

Wang

Chia

et al. 2018

Journal of Clinical Nursing

View full text Add to dashboard Cite

show abstract

Effect of Nonpharmacologic Pain Control During Examination for Retinopathy of Prematurity

Cited by 13 publications

References 19 publications

Comparison of the Pain-relieving Effects of Human Milk, Sucrose, and Distilled Water during Examinations for Retinopathy of Prematurity: A Randomized Controlled Trial

Comparison of the Pain-relieving Effects of Human Milk, Sucrose, and Distilled Water during Examinations for Retinopathy of Prematurity: A Randomized Controlled Trial

Effectiveness of Gentle Human Touch for Pain Control During Examination for Retinopathy of Pre-maturity: A Randomized Controlled Trial

A modified developmental care bundle reduces pain and stress in preterm infants undergoing examinations for retinopathy of prematurity: A randomised controlled trial

Contact Info

Product

Resources

About