Effect of nesfatin-1 on the nutritional status of hemodialysis patients

Elthakaby, AhmedH M.; Elsayed, HudaM; Mohamed, NagwaAbd El-Ghaffar; Ahmed, KarimaYoussef; Mohamed, R. I.; Esso, HanyY

doi:10.4103/jmisr.jmisr_31_21

J Med Sci Res

2022

DOI: 10.4103/jmisr.jmisr_31_21

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Effect of nesfatin-1 on the nutritional status of hemodialysis patients

AhmedH M. Elthakaby¹,

HudaM Elsayed

NagwaAbd El-Ghaffar Mohamed

et al.

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2024

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Nesfatin-1: A Novel Diagnostic and Prognostic Biomarker in Digestive Diseases

Damian-Buda,

Matei,

Ciobanu

et al. 2024

Biomedicines

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Nesfatin-1, deriving from a precursor protein, NUCB2, is a newly discovered molecule with anti-apoptotic, anti-inflammatory, antioxidant, and anorexigenic effects. It was initially identified in the central nervous system (CNS) and received increasing interest due to its energy-regulating properties. However, research showed that nesfatin-1 is also expressed in peripheral tissues, including the digestive system. The aim of this review is to give a résumé of the present state of knowledge regarding its structure, immunolocalization, and potential implications in diseases with inflammatory components. The main objective was to focus on its clinical importance as a diagnostic biomarker and potential therapeutic molecule in a variety of disorders, among which digestive disorders were of particular interest. Previous studies have shown that nesfatin-1 regulates the balance between pro- and antioxidant agents, which makes nesfatin-1 a promising therapeutic agent. Further in-depth research regarding the underlying mechanisms of action is needed for a better understanding of its effects.

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Nesfatin-1: A Novel Diagnostic and Prognostic Biomarker in Digestive Diseases

Damian-Buda,

Matei,

Ciobanu

et al. 2024

Biomedicines

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Effect of nesfatin-1 on the nutritional status of hemodialysis patients

Cited by 1 publication

References 0 publications

Nesfatin-1: A Novel Diagnostic and Prognostic Biomarker in Digestive Diseases

Nesfatin-1: A Novel Diagnostic and Prognostic Biomarker in Digestive Diseases

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