Effect of nano‐sized, elemental selenium supplement on the proteome of chicken liver

Gulyás, Gabriella; Csősz, Éva; Prokisch, József; Jávor, András; Mézes, Miklós; Erdélyi, Márta; Balogh, Krisztián; Janáky, Tamás; Szabó, Z. G.; Simon, Ádám; Czeglédi, Levente

doi:10.1111/jpn.12459

Cited by 26 publications

(18 citation statements)

References 59 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, the question remains how elemental Se can be involved in SeCys synthesis and selenoprotein expression. There are several reports of successful testing of nano-Se in broiler nutrition (Wang, 2009;Zhou and Wang, 2011;Cai et al, 2012;Gulyas et al, 2017). In many cases, its low Se toxicity is considered the main advantage of nano-Se.…”

Section: Selenium Nanoparticle (Nano-se) Productsmentioning

confidence: 99%

Selenium in Poultry Nutrition: from Sodium Selenite to Organic Selenium Sources

et al. 2018

View full text Add to dashboard Cite

Selenium (Se) is an essential element in poultry nutrition and its bio-efficacy depends on its chemical form. A growing body of research proves that organic forms of Se, mainly selenomethionine (SeMet), in poultry diets have a range of important advantages over traditional sodium selenite. In fact, the organic Se concept considers SeMet as a storage form of Se in the chicken body. As chickens are not able to synthesize SeMet, its provision through diet is a key strategy to fight commercially relevant stresses. Indeed, in stress conditions, when increased selenoprotein expression requires additional Se, while its provision via feed usually decreases due to a reduction in feed consumption, Se reserves in the body (mainly in the muscles) could help maintain an effective antioxidant defense and prevent detrimental consequences of stresses. The poultry industry is looking for the most effective sources of organic Se for commercial use. In this review, advantages and disadvantages of main organic Se sources for poultry (Se-yeast, SeMet, and OH-SeMet) are analyzed, and future directions for the development of new Se sources are identified.

show abstract

Section: Selenium Nanoparticle (Nano-se) Productsmentioning

confidence: 99%

Selenium in Poultry Nutrition: from Sodium Selenite to Organic Selenium Sources

et al. 2018

View full text Add to dashboard Cite

show abstract

“…[ 61 ] and Gulyas et al . [ 62 ] also recorded significant increases of immunoglobulin concentration in broilers supplemented with NS and they attributed the increase in the immunoglobulin levels to the enhancing influence of NS on protein synthesis and through increasing the eukaryotic translation initiation factor 5A-1, which contributed in the increase of protein synthesis, and thus increased IgG and M concentrations. Da Silva et al .…”

Section: Discussionmentioning

confidence: 99%

Prophylactic impact of nano-selenium on performance, carcasses quality, and tissues' selenium concentration using reversed-phase high-performance liquid chromatography during microbial challenge in broiler chickens

Soliman

Mahmoud²,

Fadel

et al. 2020

Vet World

View full text Add to dashboard Cite

Background and Aim: Nano-selenium (NS) supplementation contributes in improving productivity, performance, and meat quality while reducing public health concern. Influence of NS and inorganic selenium (Se) water additive on performance, carcass quality, immunoglobulin concentration, intestinal microbiota, Se tissue concentrations, and tissue architecture was studied. Materials and Methods: Two-hundred and sixty 1-day-old Hubbard chicks were randomly grouped into five groups (5×52) and supplemented with 0.5 and 1.0 mL of NS and inorganic Se (100 mg.L-1). G1, G2, G3, and G4 were challenged with Escherichia coli O157: H7 2.6×108 on the 14th day. A total of 2250 samples, including 250 sera, 250 intestinal swabs, and 1500 organ and tissue samples as liver, spleen, heart, bursa, intestine, and breast muscles, and 250 eviscerated carcasses were collected. Results: The results revealed a highly significant increase (p<0.01) in live body weights, weight gains, performance indices, carcasses, and organs weights, whereas immunoglobulin G and M concentrations in broilers treated with 0.5 and 1.0 mL NS, respectively, synchronized reveal a highly significant decline (p<0.01) in total bacterial and Enterobacteriaceae counts of intestinal swabs and breast muscles, final pH24, and drip loss in broilers treated with 0.5 and 1.0 mL NS, respectively. Meanwhile, water holding capacity revealed no significant differences between all groups. Reversed-phase high-performance liquid chromatography examination revealed the earlier disappearance of NS residues than inorganic Se from the broiler's liver and muscles. Histopathological photomicrographs of the liver, spleen, bursa of Fabricius, and intestine, as well as, the immunohistochemistry of intestinal sections revealed superior tissue architecture in broilers treated with NS contrary to inorganic Se. Conclusion: The study showed significant stimulation actions of NS on performance, immunity, carcass and meat quality, intestinal and muscles' bacterial load as well as short withdrawal period and nearly normal cellular architecture compared to inorganic Se.

show abstract

“…The present results revealed a positive influence of supplemental NS on serum concentrations of immunoglobulin G and immunoglobulin M in Ross and Arbor broilers. The enhanced levels of immunoglobulins were explained by Xiao et al (2016) and Gulyas et al (2016) as resulting from nanoselenium increasing protein synthesis and folding because there was a greater level of the eukaryotic translation initiation factor 5A-1. This factor is an important member of the protein synthesis pathway, hence the increased immunoglobulin G and immunoglobulin M serum concentrations.…”

Section: Tablementioning

confidence: 99%

Selenium and nano-selenium ameliorations in two breeds of broiler chickens exposed to heat stress

Hassan¹,

Soliman²,

Hamad³

et al. 2020

SA J. An. Sci.

View full text Add to dashboard Cite

The objective of this study was to compare the effects of synthesized nano-selenium (NS) and commercial inorganic selenium (Se) on immunity, behaviour, and performance of Arbor (AB) and Ross (RB) broilers that were exposed to heat stress of 40 °C for 6 - 8 hours daily over 38 days. Two hundred and ten one-day-old broilers of two breeds were supplemented with 0.5 mL/L of NS or Se in their drinking water. Two hundred sera, 200 intestinal swabs, and 1000 internal organ and tissue samples were collected. Weight gain, performance index, behavioral indices, total antioxidant capacity, malondialdehyde, superoxide dismutase, immunoglobulin G, immunoglobulin M, serum total protein, albumin, alanine aminotransferase, aspartate aminotransferase, and serum creatinine concentrations increased (P <0.01) in RB compared with AB when supplemented with NS. Meanwhile, NS supplementation decreased (P <0.01) water intake and the logarithmic bacterial counts of the intestine and breast in RB and AB, respectively. Histopathology revealed mild leukocytic infiltration and mild vacuolar degeneration in hepatocytes, and focal leukocytic infiltration, mild congestion, and cytoplasmic vacuolation in the myocardium of RB. Photomicrographs showed a mild lymphoid depletion in the spleen, while histopathology of the bursa of Fabricius revealed a normal follicular epithelium and normal lymphoid follicles with mild inter-follicular fibrosis in RB that were supplied with NS as opposed to AB, which expressed more severe pathological affections from heat stress. Thus, NS was more effective than Se in allowing broilers to respond to heat stress.Keywords: behaviour, immunity, growth traits, tissue architecture

show abstract

Effect of nano‐sized, elemental selenium supplement on the proteome of chicken liver

Cited by 26 publications

References 59 publications

Selenium in Poultry Nutrition: from Sodium Selenite to Organic Selenium Sources

Selenium in Poultry Nutrition: from Sodium Selenite to Organic Selenium Sources

Prophylactic impact of nano-selenium on performance, carcasses quality, and tissues' selenium concentration using reversed-phase high-performance liquid chromatography during microbial challenge in broiler chickens

Selenium and nano-selenium ameliorations in two breeds of broiler chickens exposed to heat stress

Contact Info

Product

Resources

About