Effect of music therapy on the developing central nervous system of rats.

Abstract

This research was conducted to investigate the influence of music therapy on the behavior of rats at different stages of development. The procedures were performed when animals were approximately 1 month of age, and repeated once they completed 2, 3, and 4 months. Mozart's Sonata for Two Pianos was played at a sound intensity of 65 dB for 4 hours per day, 2 hours in the morning and 2 hours in the afternoon (12 hours, for 4 days) when the animals reached each age. In the Open Field test, the locomotion in rats with 4 months old was significantly less than in other ages. Female rats 1, 2, and 3 months old, which were exposed to music, increased the percentage of open arms time in the Elevated Plus Maze test while male rats 1 month old reduced this parameter. The statistical differences were observed in the Forced Swimming test only when both genders were 1 month old. In the Inhibitory Avoidance test, an improvement in age-dependent memory was observed. The music therapy based on Mozart's Sonata for Two Pianos positively interfered with the behavior of rats at different developmental stages. This result corroborates the clinical practice of palliative care, in which music therapy is generally used to improve patients' quality of life with anxiety and depression.

Müziğin strese bağlı indüklenen hormonlar ve oksidatif stres üzerine etkisi

“…In a study, sub-chronic exposure (100 Db; 4h/day for 15 days) to noise produced increase in immobility time indicating a depression like behavior in rats 19 . However, there are also previous studies showing that music can ameliorate depression-like behavior in experimental animal 20 . On the other hand, they observed that depressive behavior had opposite levels at the juvenile age and at the adult age 20 .…”

“…However, there are also previous studies showing that music can ameliorate depression-like behavior in experimental animal 20 . On the other hand, they observed that depressive behavior had opposite levels at the juvenile age and at the adult age 20 . In addition, most of the studies which investigated the effects of classical music showed an amelioration on the structure of brain cells and neurochemistry following an improved behavior like enhanced spatial memory or decreased anxiety.…”

The impact of national music activities on improving long-term care for happiness of elderly people

“…Relevant studies have shown that music has a positive impact on the mental and physical health of silver-haired people ( Vinciguerra, 2017 ). Therefore, it is a major direction of music research to improve the physical and mental health of silver-haired people by making them contact with music ( Sampaio et al, 2017 ). However, with increasing age, the physiological function and physical quality of the silver-haired group gradually degenerated, and most of the silver-haired group did not want to move.…”