Effect of moxa smoke on sperm parameters and oxidative stress in rats with asthenozoospermia

Liu, Yajie; An, Yu; Xing, Guo-Gang; Jin, Zi-Run; Xi, Ke; Huo, Yujia; He, Rui; Wang, Hao; Ouyang, Xiali; Huang, Yueping; Huang, Chang; Han, Li; Zhao, Baixiao

doi:10.1002/ar.25002

Cited by 4 publications

(2 citation statements)

References 30 publications

(32 reference statements)

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“…However, all results surprisingly demonstrated clinical efficacy and safety of MS under the carefully designed concentration, totally out of expectations. [58][59][60][61][62][63] Therefore, our hypothesis is that the efficacy and safety of MS possibly should be affected by the level of MSC, moxa quality and duration of exposure in MS. Firstly, moxa aged more than three years is considered as quality guarantee for its characteristics, and the moxibustion duration usually lasts for 20-30 min for each session. 64 Hence, moxa that has been aged for three years will be utilized in 30-minute treatment sessions in this trial.…”

Section: Discussionmentioning

confidence: 99%

Efficacy and Safety of a Novel Plum Blossom Needling with Mild Moxibustion Device for Upper Limb Pain Disorder and Motor Dysfunction in Patients with Stage 1 Post-Stroke Shoulder-Hand Syndrome: Study Protocol for a Multi-Center, Single-Blind, Randomized Sham-Controlled Trial

Meng¹,

Sun²,

Liu³

et al. 2023

JPR

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Background: Post-stroke shoulder-hand syndrome (PS-SHS), a common neurological comorbidity after stroke episodes, poses a grave threat on patients' functional recovery. Preliminary trials have demonstrated that the acupuncture and moxibustion treatment, including a dermal acupuncture tapping method known as plum blossom needling (PBN) can improve pain and motor dysfunctions in patients with PS-SHS. However, there are few reports describing simultaneous moxibustion treatment in combination with PBN. Hence, a novel plum blossom needle device with mild moxibustion (PBNMM) was developed to evaluate its potential efficacy and safety in patients with stage 1 PS-SHS. Materials and Methods: This multicenter, sham-controlled, randomized controlled trial (RCT) will recruit 102 eligible patients with stage 1 PS-SHS from three clinical centers, randomly allocated in a ratio of 1:1:1 to the PBNMM group, PBNMM with no moxa smoke (PBNMM-NMS) group and sham control group. Patients in each group will receive a 30-minute treatment once per day for 4 weeks, with 5 consecutive sessions per week, for a total of 20 sessions. The primary outcome measure will be defined as the decreased scores from baseline in the visual analog scale (VAS) assessment at week 4. Secondary outcome measures will include scores on the Fugl-Meyer Assessment of the Upper Extremity Scale (FMA-UE), the Modified Barthel Index (MBI), and the somatosensory evoked potential (SEP) records. All outcomes will be evaluated at baseline and weeks 4, 5, 6 and 10, and the intention-to-treat analysis will be applied. Conclusion:This study aims to provide robust evidence for the efficacy and safety of the PBNMM for PS-SHS treatment, as well as the specific impact of moxibustion smoke itself in dealing with PS-SHS.

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Section: Discussionmentioning

confidence: 99%

Efficacy and Safety of a Novel Plum Blossom Needling with Mild Moxibustion Device for Upper Limb Pain Disorder and Motor Dysfunction in Patients with Stage 1 Post-Stroke Shoulder-Hand Syndrome: Study Protocol for a Multi-Center, Single-Blind, Randomized Sham-Controlled Trial

Meng¹,

Sun²,

Liu³

et al. 2023

JPR

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“…In another study on male reproductive system diseases, Liu et al (2023) analyzed the effects of different concentrations of moxa smoke on sperm parameters of rats with asthenozoospermia. The results showed that the sperm activity and antioxidant enzyme activity of rats were significantly improved after moxa smoke intervention, associated with morphological and structural regeneration of testicular tissue.…”

Section: Introductionmentioning

confidence: 99%

Traditional Chinese medicine in human diseases treatment: New insights of their potential mechanisms

Zhang

Jiang

2023

The Anatomical Record

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For millennia, traditional Chinese medicine (TCM) has relieved the pain of countless patients with its unique theory and treatment method, which has provoked researchers' interest for exploring the biological and molecular mechanisms. This special issue highlights recent advances of this ancient and mysterious medical system in the basic science research field. The authors in this volume explored the molecular characteristics of TCM syndromes and the disease‐resistant mechanisms of acupuncture and Chinese herbs in the diseases effecting the human motor system, digestive system, nervous system, and other organ systems by applying high‐throughput omics technologies, molecular biology experiments, animal models and other methods. Alongside enhancing their perception of TCM from these latest findings, readers can also understand how to cross the systematic theory of TCM with modern molecular biology techniques. These studies advance our understanding of the potential mechanisms of TCM in treating human diseases, and also provide inspiration for the development of novel TCM‐based therapeutic strategies. We hope these efforts will promote extensive development in TCM research.

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Moxibustion prevents tripterygium glycoside-induced oligoasthenoteratozoospermia in rats via reduced oxidative stress and modulation of the Nrf2/HO-1 signaling pathway

Liang,

Yin,

Zhang

et al. 2024

Aging

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Effect of moxa smoke on sperm parameters and oxidative stress in rats with asthenozoospermia

Cited by 4 publications

References 30 publications

Efficacy and Safety of a Novel Plum Blossom Needling with Mild Moxibustion Device for Upper Limb Pain Disorder and Motor Dysfunction in Patients with Stage 1 Post-Stroke Shoulder-Hand Syndrome: Study Protocol for a Multi-Center, Single-Blind, Randomized Sham-Controlled Trial

Efficacy and Safety of a Novel Plum Blossom Needling with Mild Moxibustion Device for Upper Limb Pain Disorder and Motor Dysfunction in Patients with Stage 1 Post-Stroke Shoulder-Hand Syndrome: Study Protocol for a Multi-Center, Single-Blind, Randomized Sham-Controlled Trial

Traditional Chinese medicine in human diseases treatment: New insights of their potential mechanisms

Moxibustion prevents tripterygium glycoside-induced oligoasthenoteratozoospermia in rats via reduced oxidative stress and modulation of the Nrf2/HO-1 signaling pathway

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