Effect of Monosodium Glutamate on Some Vitamins and the Protective role of Vitamin B12 in Adult Female Rats

Abstract

The aim of study: the current study investigated the effect of MSG and protective role of Vitamin B 12 on the Vitamin C and E concentration level in rats, material and method, the study included Rats were divided into five equal groups n=10, each group was further divided into two groups [A and B, n=5] and treated for 30 and 60 days, respectively. The 1st group received distilled water orally by gavage, the 2nd and 3rd group received MSG in a dose of 20, and 40 mg/kg body weight orally by gavage, respectively, the 4th and 5th groups received MSG and vitamin B12 in a dose of 20 or 40 mg MSG/kg in addition to 0.2 m vitamin B12/kg, respectively. The results: The findings found the Group V showed increased in Vitamin C concentration after 30 and 60 days (1.246±0.319, 1.335±0.341) respectively with significant differences with other groups same results reported in Vitamin E that showed Vitamin E concentration after 30 and 60 day (1.136±0.319, 1.109±0.019) respectively with significant differences at (p≤0.05) with other groups.