Effect of moderate arterial hypotension combined with repeated withdrawal of cerebrospinal fluid on the development of increased ventricular fluid pressure after cold injuries in cats

Maas, Andrew I. R.; Lange, S. A. de

doi:10.1016/0303-8467(76)90002-0

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1977

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“…The systemic effects of trimetaphan and the effect of hypotension on the development of increased ventricular fluid pressure after cold injuries in cats have been described elsewhere (Maas and de Lange, 1977). The results reported in this paper concentrate on the effect of hypotension on the changes in CSF enzyme activity.…”

Section: Resultsmentioning

confidence: 93%

Cerebrospinal fluid enzymes in acute brain injury: 3 Effect of hypotension on increase of CSF enzyme activity after cold injury in cats

Maas

1977

Journal of Neurology, Neurosurgery & Psychiatry

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SUMMARY The influence of trimetaphan-induced hypotension was studied on the increase in the activities of various enzymes in the cerebrospinal fluid after cold injuries of the brain in cats. Hypotension was induced immediately after freezing, and in a second series after a delay of 45 minutes. It was shown that induction of hypotension may inhibit the appearance of enzymes in the CSF after cold injuries in the first seven hours after freezing. Histological studies revealed less pronounced oedema in the hypotensive animals. The results suggest that hypotension retards the transport of enzymes released from necrotic areas through the extracellular fluid towards the CSF.

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Section: Resultsmentioning

confidence: 93%

Cerebrospinal fluid enzymes in acute brain injury: 3 Effect of hypotension on increase of CSF enzyme activity after cold injury in cats

Maas

1977

Journal of Neurology, Neurosurgery & Psychiatry

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show abstract

Effect of moderate arterial hypotension combined with repeated withdrawal of cerebrospinal fluid on the development of increased ventricular fluid pressure after cold injuries in cats

Cited by 1 publication

References 19 publications

Cerebrospinal fluid enzymes in acute brain injury: 3 Effect of hypotension on increase of CSF enzyme activity after cold injury in cats

Cerebrospinal fluid enzymes in acute brain injury: 3 Effect of hypotension on increase of CSF enzyme activity after cold injury in cats

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