Effect of micronutrient supplementation on health and nutritional status of schoolchildren: growth and morbidity

Sarma, K. V. Rameshwar; Udaykumar, Putcha; Balakrishna, Nagalla; Vijayaraghavan, K.; Sivakumar, B.

doi:10.1016/j.nut.2005.07.011

Cited by 34 publications

(30 citation statements)

References 22 publications

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“…In contrast, and similar to the present study, supplementation with iron and zinc did not result in a reduction of severe diarrhea in Bangladeshi infants (Baqui et al, 2003) or in Peruvian children who received zinc along with vitamins and other minerals (Sarma et al, 2006). Two other studies in different settings have also shown negligible impact of MN supplementation on morbidity (Lopriore et al, 2004;Kelly et al, 2008).…”

Section: Discussionsupporting

confidence: 79%

“…It is reasonable to surmise that this might have been because of the pre existing low incidence (0-1 events per child/year) of more serious symptoms in this group of children. For example, the incidence of diarrhea in the first one month of intervention was only 0.3 per 100 days, which is comparable to incidences reported in other school-aged children (Sarma et al, 2006) but much lower than incidences reported in younger children (4.86 episodes per 100 days) (Penny et al, 2004).…”

Section: Discussionsupporting

confidence: 41%

“…A study in Thai children of 5-13 years of age, demonstrated a significantly beneficial effect of a MN fortified seasoning powder on the incidence of respiratory-related illness such as cough and runny nose and diarrhea (Manger et al, 2008). Similarly, in Indian children aged 5-14 years, a multiple MN fortified beverage was effective in reducing the mean duration of illness significantly with 2.4 days compared with an unfortified beverage (Sarma et al, 2006). Furthermore, South African children aged 6-11 years receiving a fortified biscuit and drink with iron, iodine, vitamin C and b-carotene for 12 months missed significantly fewer school days owing to respiratory-related illness (14 days/100 children) and diarrhea (17 days/100 children) compared with control children (van Stuijvenberg et al, 1999).…”

Section: Discussionmentioning

confidence: 99%

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The effect of a 1-year multiple micronutrient or n-3 fatty acid fortified food intervention on morbidity in Indian school children

et al. 2011

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Background/Objectives: Few studies have shown that supplementation with micronutrients (MNs) or n-3 fatty acids may have health benefits such as reduced morbidity in schoolchildren. The effect of a combination of these nutrients has never been investigated. This study aimed to determine the effect of a combination of two different doses of MN and n-3 fatty acids on morbidity in schoolchildren in Bangalore, India. Subjects/Methods: In all 598 children (6-10 years) received foods fortified with either high (100% recommended dietary allowance) or low (15% recommended dietary allowance) MN, combined with either high (900 mg a-linolenic acid (ALA) plus 100 mg docosahexaenoic acid) or low (140 mg ALA) n-3 fatty acids for 1 year. Morbidity was measured by weekly self-reports using a structured questionnaire. Poisson regression analyses of episodes/child/year and duration/episode adjusted for age and sex were performed on clusters of symptoms, including upper and lower respiratory tract infections (URTI and LRTI), gastrointestinal complaints (GI) and general symptoms of illness to observe MN and n-3 fatty acid treatment effects. Conclusion: Although n-3 fatty acids may be beneficial for reducing illness in Indian schoolchildren, more research is needed to confirm presence of combined effect with MN.

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Section: Discussionsupporting

confidence: 79%

Section: Discussionsupporting

confidence: 41%

Section: Discussionmentioning

confidence: 99%

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The effect of a 1-year multiple micronutrient or n-3 fatty acid fortified food intervention on morbidity in Indian school children

et al. 2011

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“…A randomized placebo control trial among Iranian children aged 8-11 years, when given zinc (10 mg/day) daily for 6 days per week, for 7 months reported a significant increase in weight and length (Ebrahimi et al, 2006). A recent study in India (Sarma et al, 2006) also has shown a significant increase in mean increments of HAZ and HAZ among school children aged 6-16 years when supplemented with a micronutrient fortified beverage (iron, zinc, calcium, folic acid, vitamins and iodine are the key ingredients) for a period of 14 months.…”

Section: Effect On Anthropometrymentioning

confidence: 97%

The efficacy of micronutrient supplementation in reducing the prevalence of anaemia and deficiencies of zinc and iron among adolescents in Sri Lanka

et al. 2007

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Objective: To determine the effectiveness of combined iron and zinc over the iron or zinc-only supplementation in correcting deficiency and possible interactive effects in a group of adolescent school children. Subjects and methods: Schoolchildren (n ¼ 821) of 12-16 years of age were randomized into four groups and supplemented with iron (50 mg/day), zinc (14 mg/day), iron þ zinc or placebo capsules 5 days per week for 24 weeks. Anthropometry, and haemoglobin (Hb), serum zinc (SZn) and serum ferritin (SF) concentrations were determined before and after the intervention. Results: There were no significant effects between-groups in their weight, height and Hb concentrations with the intervention when compared with the placebo group. Iron-only and combination-supplemented groups had reached mean SF concentrations of 55.1 mg/l with no difference between them (P ¼ 0.99). The zinc-only group had a mean change of 4.3 mmol//l whereas the combine-supplemented group had a mean change of 4.0 mmol/l (P ¼ 0.82). The prevalence of anaemia was found to be 70.3% in the iron group at baseline; this was reduced to 14.5% after the supplementation. In the combinesupplemented group anaemia, prevalence was reduced from 64.8 to 19.3%. Conclusions: Zinc alone or in combination with iron has not shown a significant improvement in growth in adolescence. Severe and moderate forms of anaemia were successfully treated in children who received iron supplementation. Initial high prevalence of low SZn and iron stores was significantly improved with micronutrient supplementation.

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“…A double-blind, placebo-controlled, matched-pair, cluster-randomized study by Sarma et al evaluated the effect of a micronutrientfortified beverage on growth and morbidity in a total of 869 apparently healthy school children of 6-16 years of age. Anthropometrics, clinical symptoms of deficiency and morbidity data were collected at baseline in the supplemented group (n=446) and the placebo group (n=423) and after 14 months of supplementation (n=355, supplement group and n=340, placebo) [51]. Nutrient composition of basal formulation, common to both the supplementary and placebo groups, consisted of wheat flour, malted barley, skimmed milk powder and sugar providing 7.3 g protein, 2 g fat, 208 kcal energy and 176 mg of calcium.…”

Section: Role Of Supplements In Achieving Genetic Growth Potentialmentioning

confidence: 99%

Protein and Micronutrient Supplementation in Complementing Pubertal Growth

Jacob¹,

Nair²

2011

Indian J Pediatr

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For several reasons, adolescence is considered as a nutritionally critical period of life. The dramatic increase in physical growth and development puts greater pressure on the need for nutrients, as it is during this period when adolescents experience a weight gain equivalent to 65% of their weight at the beginning of the period or 40% of their final weight, and a height gain equivalent to 15% of their adult height. The requirement of some of the nutrients is as high as, or higher in adolescents than in any other age groups. Moreover, adolescence is a time where the life-style and food habits are influenced by socio-cultural factors resulting in an imbalance in nutrient intake and nutrient inadequacy can result in delayed sexual maturation and can arrest or slow linear growth. With the increasing prevalence of hidden malnutrition among Indian children, adolescence can be the second opportunity to catch up growth and cover the deficits suffered during childhood and to meet the demands of physical and cognitive growth and development, provide adequate stores of energy for illnesses and pregnancy, and prevent adult onset of nutrition-related diseases. Adolescents should be recognized as a priority target group as an integral part of health promotion and optimal nutrition through balanced diet and nutrient supplementation should be promoted in conjunction with healthy eating habits and physical activity.

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Effect of micronutrient supplementation on health and nutritional status of schoolchildren: growth and morbidity

Cited by 34 publications

References 22 publications

The effect of a 1-year multiple micronutrient or n-3 fatty acid fortified food intervention on morbidity in Indian school children

The effect of a 1-year multiple micronutrient or n-3 fatty acid fortified food intervention on morbidity in Indian school children

The efficacy of micronutrient supplementation in reducing the prevalence of anaemia and deficiencies of zinc and iron among adolescents in Sri Lanka

Protein and Micronutrient Supplementation in Complementing Pubertal Growth

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