Effect of microalgae as iron supplements on iron-deficiency anemia in rats

Gao, Fengzheng; Guo, Wei; Zeng, Mingyong; Feng, Yahui; Feng, Guangxin

doi:10.1039/c8fo01834k

Cited by 23 publications

(10 citation statements)

References 50 publications

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“…The results corroborate the earlier study reporting improvement in haematological parameters with supplementation of Spirulina fortified diets. 49 The present study indicates that the iron from Spirulina is bioavailable, resulting in restoration and improvement of haematological parameters.…”

Section: Resultssupporting

confidence: 57%

Arthrospira platensis (Spirulina) fortified functional foods ameliorate iron and protein malnutrition by improving growth and modulating oxidative stress and gut microbiota in rats

Kumar

Das

et al. 2023

Food Funct.

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Section: Resultssupporting

confidence: 57%

Arthrospira platensis (Spirulina) fortified functional foods ameliorate iron and protein malnutrition by improving growth and modulating oxidative stress and gut microbiota in rats

Kumar

Das

et al. 2023

Food Funct.

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“…Haemoglobin and MCH concentrations increased after TC supplementation in SG ( p < 0.01 in haemoglobin; p < 0.05 in MCH). Microalgae have been used in animals as supplements to improve iron deficiencies [ 47 ]. Nasirian et al (2017) investigated the effects of Spirulina platensis (15 and 30 mg/kg body weight) for five weeks on haematological parameters in diabetic rats [ 48 ].…”

Section: Discussionmentioning

confidence: 99%

Effects of Tetraselmis chuii Microalgae Supplementation on Ergospirometric, Haematological and Biochemical Parameters in Amateur Soccer Players

Toro

Siquier-Coll

Bartolomé

et al. 2020

IJERPH

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This study aimed to analyse the effects of Tetraselmis chuii (TC) microalgae supplementation during thirty days on ergospirometric, haematological and biochemical parameters in amateur soccer players. Thirty-two amateur soccer players divided into a control group (CG; n = 16; 22.36 ± 1.36 years; 68.36 ± 3.53 kg) and a supplemented group (SG; n = 16; 22.23 ± 2.19 years; 69.30 ± 5.56 kg) participated in the double-blind study. SG ingested 200 mg of the TC per day, while CG ingested 200 mg per day of lactose powder. Supplementation was carried out for thirty days. The participants performed a maximal treadmill test until exhaustion. The ergospirometric values at different ventilatory thresholds and haematological values were obtained after the test. Heart rate decreased after supplementation with TC (p < 0.05). Oxygen pulse, relative and absolute maximum oxygen consumption increased in SG (pre vs. post; 19.04 ± 2.53 vs. 22.08 ± 2.25; 53.56 ± 3.26 vs. 56.74 ± 3.43; 3.72 ± 0.35 vs. 3.99 ± 0.25; p < 0.05). Haemoglobin and mean corpuscular haemoglobin increased in SG (pre vs. post; 15.12 ± 0.87 vs. 16.58 ± 0.74 p < 0.01; 28.03 ± 1.57 vs. 30.82 ± 1.21; p < 0.05). On the other hand, haematocrit and mean platelet volume decreased in SG (p < 0.05). TC supplementation elicited improvements in ergospirometric and haematological values in amateur soccer players. TC supplementation could be valuable for improving performance in amateur athletes.

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“…Thus, people on vegan and vegetarian diets may be at risk for iron-deficiency anemia [63]. Studies in rats and humans have investigated whether Chlorella supplementation can prevent iron-deficiency anemia [67,68]. In a cohort of 32 women in the second and third trimester of pregnancy, oral Chlorella supplementation (6 g/day) for 12-18 weeks decreased markers of anemia as compared to the control group [68], suggesting that Chlorella supplementation significantly reduces the risk of pregnancy-associated anemia.…”

Section: Mineralsmentioning

confidence: 99%

Potential of Chlorella as a Dietary Supplement to Promote Human Health

Bito

Okumura²,

Fujishima³

2020

Nutrients

137

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Chlorella is a green unicellular alga that is commercially produced and distributed worldwide as a dietary supplement. Chlorella products contain numerous nutrients and vitamins, including D and B12, that are absent in plant-derived food sources. Chlorella contains larger amounts of folate and iron than other plant-derived foods. Chlorella supplementation to mammals, including humans, has been reported to exhibit various pharmacological activities, including immunomodulatory, antioxidant, antidiabetic, antihypertensive, and antihyperlipidemic activities. Meta-analysis on the effects of Chlorella supplementation on cardiovascular risk factors have suggested that it improves total cholesterol levels, low-density lipoprotein cholesterol levels, systolic blood pressure, diastolic blood pressure, and fasting blood glucose levels but not triglycerides and high-density lipoprotein cholesterol levels. These beneficial effects of Chlorella might be due to synergism between multiple nutrient and antioxidant compounds. However, information regarding the bioactive compounds in Chlorella is limited.

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Effect of microalgae as iron supplements on iron-deficiency anemia in rats

Abstract: Microalgae are functional iron nutritive fortifiers that can supply more intestinal nanosized iron.

Cited by 23 publications

References 50 publications

Arthrospira platensis (Spirulina) fortified functional foods ameliorate iron and protein malnutrition by improving growth and modulating oxidative stress and gut microbiota in rats

Arthrospira platensis (Spirulina) fortified functional foods ameliorate iron and protein malnutrition by improving growth and modulating oxidative stress and gut microbiota in rats

Effects of Tetraselmis chuii Microalgae Supplementation on Ergospirometric, Haematological and Biochemical Parameters in Amateur Soccer Players

Potential of Chlorella as a Dietary Supplement to Promote Human Health

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