Effect of metabolic syndrome and of its individual components on renal function of patients with type 2 diabetes mellitus

High Serum Adipocyte Fatty Acid Binding Protein Is Associated with Metabolic Syndrome in Patients with Type 2 Diabetes

“…MetS and its components are associated with the development of chronic kidney disease and microalbuminuria or overt proteinuria [16]. Type 2 DM patients with MetS are associated with the reduction of GFR [14]. Our study also noted that MetS in patients with type 2 DM had higher serum BUN level and lower GFR.…”

“…The prevalence of MetS was 46.9% for males and 65.1% for females in type 2 DM patients in a Korean study [13] and 78.6% in type 2 DM patients in Brazil [14]. In this study, the prevalence of MetS in type 2 DM patients is 68.5%.…”

Metabolic syndrome and its components are associated with increased chronic kidney disease risk: Evidence from a meta-analysis on 11 109 003 participants from 66 studies

“…Among the included studies, 43 were from the East Asian populations 8,9,[22][23][24][25][27][28][29]33,[35][36][37][38][39][40][41]43,44,51,52,[55][56][57][58][59]62,[65][66][67]69,[71][72][73][74][75][76][77][78][79][80]82,83 and 23 were from non-East Asian populations. 12,20,21,26,[30][31][32]34,42,…”

Insulin resistance as a predictor of cardiovascular morbidity and end-stage renal disease

“…Cardiovascular disease (CVD) is the leading cause of death in chronic kidney disease (CKD) patients with a higher incidence than in general population, even after adjusting for age and diabetic status (Caravaca, Cerezo, Macías, et al, 2010;Fragoso, Silva, Gundlach, et al, 2014;Liao, Sung, Hung, et al, 2012;Moehlecke, Leitão, Kramer, et al, 2010). This increased cardiovascular morbidity and mortality progressively increases with the decline of the glomerular filtration rate (GFR) and cannot be explained only by traditional risk factors (Liao et al, 2012).…”