Effect of melanocyte keratinocyte transplantation procedure, using ablative CO<sub>2</sub> laser and followed by NB-UVB phototherapy, on the expression of E-Cadherin and matrix metalloproteinase-2 in acral vitiligo: an immunohistochemical study

Background: Transplantation plays a pivotal role in vitiligo surgery and has advanced at a galloping pace.Objectives: To enlist the latest developments in vitiligo transplantation surgery.Findings: Advancements in clinico-epidemiological and molecular profiling (CD8, CD45RO, CXCL-9) have enabled us to predict response to treatment better than ever before. The pace of transplantation has been augmented and the hassle of properly orienting the graft has been bypassed. The pallet has been expanded with a better donor to recipient ratio and ease of technique with regard to hair follicle transplants and suspensions. Suspending media have had a makeover, becoming less runner with a greater rate of pigmentation. Science has made the procedure more pocket and equipment friendly, be it in the realm of incubation or inhibition of trypsin. Electrofulguration, cryogens, salicylic and lactic acid, dental burrs, and lasers have made recipient site preparation easier. Adversity has been metamorphosed into an advantage by harvesting and transplanting the cobblestone that appears post-mini-punch grafting. Surgical techniques have been crafted to conform to special sites like the fingers, palmoplantar sites, ears, genitals, and nipple-areola. Conclusion:There have been many significant advancements in the field of vitiligo transplantation surgery in recent years especially in terms of ease of technique, minimal invasiveness, the pain associated with the procedure, and success rates.

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Transplantation procedures in vitiligo: What's new

Thakur

Parsad

2022

Dermatological Reviews

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Effect of melanocyte keratinocyte transplantation procedure, using ablative CO₂ laser and followed by NB-UVB phototherapy, on the expression of E-Cadherin and matrix metalloproteinase-2 in acral vitiligo: an immunohistochemical study

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Transplantation procedures in vitiligo: What's new

Transplantation procedures in vitiligo: What's new

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Effect of melanocyte keratinocyte transplantation procedure, using ablative CO2 laser and followed by NB-UVB phototherapy, on the expression of E-Cadherin and matrix metalloproteinase-2 in acral vitiligo: an immunohistochemical study

Cited by 1 publication

References 1 publication

Transplantation procedures in vitiligo: What's new

Transplantation procedures in vitiligo: What's new

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Product

Resources

About

Effect of melanocyte keratinocyte transplantation procedure, using ablative CO₂ laser and followed by NB-UVB phototherapy, on the expression of E-Cadherin and matrix metalloproteinase-2 in acral vitiligo: an immunohistochemical study