“…Of these 16 articles, 8 met the inclusion criteria for the first endpoint [ 15 , 16 , 18 , 20 , 21 , 25 – 27 ], 4 for the second endpoint [ 14 , 18 , 20 , 22 ], 2 for the third endpoint [ 19 , 24 ] and 4 for the fourth endpoint [ 17 , 23 , 28 , 29 ].…”
Section: Resultsmentioning
confidence: 99%
“…Four studies compared effects of different strategies of MH for amniotic fluid improvement in pregnant women with normo-hydramnios (453 women), all focused on short-term therapy (within one day). [ 17 , 23 , 28 , 29 ]. In detail two studies compared oral hypotonic fluid administration (<2000ml) versus no treatments reporting no differences in term of AFI index variation [p:n.s.].…”
ObjectiveSeveral trials aimed at evaluating the efficacy of maternal hydration (MH) in increasing amniotic-fluid-volume (AFV) in pregnancies with isolated oligohydramnios or normohydramnos have been conducted. Unfortunately, no evidences support this intervention in routine-clinical-practice. The aim of this systematic-literature-review and meta-analysis was to collect all data regarding proposed strategies and their efficacy in relation to each clinical condition for which MH-therapy was performed with the aim of increasing amniotic-fluid (AF) and improving perinatal outcomes.Materials and MethodsA systematic literature search was conducted in electronic-database MEDLINE, EMBASE, ScienceDirect and the Cochrane-Library in the time interval between 1991 and 2014. Following the identification of eligible trials, we estimated the methodological quality of each study (using QADAS-2) and clustered patients according to the following outcome measures: route of administration (oral versus intravenous versus combined), total daily dose of fluids administered (<2000 versus >2000), duration of hydration therapy: (1 day, >1 day but <1 week, >1 week), type of fluid administered (isotonic versus hypotonic versus combination).ResultsIn isolated-oligohydramnios (IO), maternal oral hydration is more effective than intravenous hydration and hypotonic solutions superior to isotonic solutions. The improvement in AFV appears to be time-dependent rather than daily-dose dependent. Regarding normohydramnios pregnancies, all strategies seem equivalent though the administration of hypotonic-fluid appears to have a slightly greater effect than isotonic-fluid. Regarding perinatal outcomes, data is fragmentary and heterogeneous and does not allow us to define the real clinical utility of MH.ConclusionsAvailable data suggests that MH may be a safe, well-tolerated and useful strategy to improve AFV especially in cases of IO. In view of the numerous obstetric situations in which a reduced AFV may pose a threat, particularly to the fetus, the possibility of increasing AFV with a simple and inexpensive practice like MH-therapy may have potential clinical applications. Considering the various strategies of maternal hydration implemented in the treatment of IO, better results were observed when treatment was based on a combination of intravenous (for a period of 1 day) and oral (for a period of at least 14 days) hypotonic fluids (≥2000ml).
“…Of these 16 articles, 8 met the inclusion criteria for the first endpoint [ 15 , 16 , 18 , 20 , 21 , 25 – 27 ], 4 for the second endpoint [ 14 , 18 , 20 , 22 ], 2 for the third endpoint [ 19 , 24 ] and 4 for the fourth endpoint [ 17 , 23 , 28 , 29 ].…”
Section: Resultsmentioning
confidence: 99%
“…Four studies compared effects of different strategies of MH for amniotic fluid improvement in pregnant women with normo-hydramnios (453 women), all focused on short-term therapy (within one day). [ 17 , 23 , 28 , 29 ]. In detail two studies compared oral hypotonic fluid administration (<2000ml) versus no treatments reporting no differences in term of AFI index variation [p:n.s.].…”
ObjectiveSeveral trials aimed at evaluating the efficacy of maternal hydration (MH) in increasing amniotic-fluid-volume (AFV) in pregnancies with isolated oligohydramnios or normohydramnos have been conducted. Unfortunately, no evidences support this intervention in routine-clinical-practice. The aim of this systematic-literature-review and meta-analysis was to collect all data regarding proposed strategies and their efficacy in relation to each clinical condition for which MH-therapy was performed with the aim of increasing amniotic-fluid (AF) and improving perinatal outcomes.Materials and MethodsA systematic literature search was conducted in electronic-database MEDLINE, EMBASE, ScienceDirect and the Cochrane-Library in the time interval between 1991 and 2014. Following the identification of eligible trials, we estimated the methodological quality of each study (using QADAS-2) and clustered patients according to the following outcome measures: route of administration (oral versus intravenous versus combined), total daily dose of fluids administered (<2000 versus >2000), duration of hydration therapy: (1 day, >1 day but <1 week, >1 week), type of fluid administered (isotonic versus hypotonic versus combination).ResultsIn isolated-oligohydramnios (IO), maternal oral hydration is more effective than intravenous hydration and hypotonic solutions superior to isotonic solutions. The improvement in AFV appears to be time-dependent rather than daily-dose dependent. Regarding normohydramnios pregnancies, all strategies seem equivalent though the administration of hypotonic-fluid appears to have a slightly greater effect than isotonic-fluid. Regarding perinatal outcomes, data is fragmentary and heterogeneous and does not allow us to define the real clinical utility of MH.ConclusionsAvailable data suggests that MH may be a safe, well-tolerated and useful strategy to improve AFV especially in cases of IO. In view of the numerous obstetric situations in which a reduced AFV may pose a threat, particularly to the fetus, the possibility of increasing AFV with a simple and inexpensive practice like MH-therapy may have potential clinical applications. Considering the various strategies of maternal hydration implemented in the treatment of IO, better results were observed when treatment was based on a combination of intravenous (for a period of 1 day) and oral (for a period of at least 14 days) hypotonic fluids (≥2000ml).
“…There are multiple causes of oligohydramnios, and management of the condition is individualized based on the maternal or fetal condition. 4 It associated with adverse perinatal outcome such as fetal distress (ante/intrapartum fetal heart rate declarations and meconium passage, cord compression), induction of labor, operative delivery and poor APGAR score at birth. 5 Hence, it is of utmost importance, to detect and treat this complication as early as possible.…”
Objective: The objective of the study was to compare mean Amniotic Fluid Index (AFI) in maternal oral hydration with routine hydration in third trimester oligohydramnios. Study design: Randomized control trial. Settings: Department of Gynea/Obs Faisalabad Medical University, Faisalabad. Duration of study: 6 months from 1 st June to 30 th November 2016. Methodology: A total of 80 cases (40 in each group), were included in the study, Group A was oral hydration group and was enquired about daily water intake. They are bound to take 2 liters of water in addition to their daily intake for 7 days. Group B was routine hydration group and continued to drink water determined by thirst and followed up on OPD basis according to the hospital protocol. Ultrasonography was done by radiology department and reported by radiologist after completion of 7 days and revised amniotic fluid index was noted. All the information was recorded on proforma. Results: In this study, (40 in each group), 65%(n=26) in Group-A and 57.5%(n=23) in Group-B were between 18-30 years and 35%(n=14) in Group-A and 42.5%(n=17) in Group-B were between 31-45 years of age, mean+sd was calculated as 27.88+5.40 years and 28.80+5.72 years respectively, pre-treatment mean AFI volume was in-significant between the two groups. Post-treatment mean AFI volume was recorded as 6.83+0.81 in Group-A and 5.05+0.75 in Group-B, p value was calculated as 0.001 which shows significant difference between the two groups. Conclusion: We concluded that oral hydration appears to be significantly increased in mean AFI as compare to routine hydration in third trimester oligohydramnios, this therapy can be used instead of expectant management or invasive techniques in patients of third trimester oligohydramnios.
“…Hasil tersebut sesuai dengan hasil penelitian Borges et al yang mendemonstrasikan peningkatan AFI secara signifikan 10 kali lipat pada ibu hamil normoamnion yang diberikan hidrasi 1,5 L cairan isotonis yang diminum selama 2-4 jam, dan peningkatan AFI 4 kali lipat pada hidrasi 1,5 L air minum. 15 Hasil uji variabel-variabel luar terhadap indeks cairan amnion, tidak mempunyai pengaruh bermakna terhadap indeks cairan amnion (P> 0,05), kecuali variabel pekerjaan (P < 0,05). Hasil uji multivariat model 1 diketahui bahwa terdapat pengaruh asupan cairan terhadap indeks cairan amnion (P< 0,05) dengan besarnya pengaruh sebesar 31,7% sedangkan sisanya 68,3% lainnya dipengaruhi oleh faktor-faktor lain.…”
Introduction: Adequate amniotic fluid volume is a requirement for intra uterine fetal development and good pregnancy outputs / neonatal. Adequate intake of fluid in pregnant women can increase both the amniotic fluid index on oligohydramniotic or normoamniotic, but the scientific basis for the adequacy of the recommended daily fluid have not clear yet. Furthermore, the fluid intake counseling in addition to nutrition for pregnant women is neededObjective: To determine the fluid intake in pregnant women and the mean difference of amniotic fluid index on adequate fluid intake compared to less fluid intake.Methods: This research used prospective observational cohort study, conducted against the third semester pregnant women in Puskesmas Mergangsan and Tegalrejo Yogyakarta during July until September 2014. The subjects who met the inclusion criteria were divided into adequate and less fluid intake groups. The correlation between fluid intake and amniotic fluid index was analyzed using t-test and linear regression.Result and Discussion: The total subjects who met the criteria were 27 people, consist of 12 people in adequate fluid intake group and 15 people in less fluid intake group. The mean of subject’s fluid intake 2078 ml (enough), while the mean of amniotic fluid index (AFI) 12,76 cm (normoamniotic).The result showed that there was a significant difference (3,50 cm (IK 95%; 1,5-5,48); P < 0,05) between the mean of AFI from adequate fluid intake group compared to less fluid intake group . Simple linear regression test showed the effect of fluid intake for AFI namely 31,7%; with the amount of predicted AFI = 10,686 + 3,545 x fluid intake – 1,015 x age – 1,317 x education + 0,314 x occupation (ARS= 44,5%). External variables (age, education, and occupation) had no significant effect for AFI .Conclusion : The mean preview of fluid intake in the third semester pregnant women in Yogyakarta was adequate. Moreover, there was a AFI signifficant difference between adequate fluid intake compared to less fluid intake. Keywords: fluid intake; amniotic fluid index; AFI
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.