Effect of Mailing an At-home Disposal Kit on Unused Opioid Disposal After Surgery

Agarwal, Anish K.; Lee, Daniel; Ali, Zarina S.; Wu, Yaxin; Cognilio, Mary; Uritsky, Tanya J.; Delgado, M. Kit

doi:10.1001/jamanetworkopen.2022.10724

Cited by 6 publications

(5 citation statements)

References 6 publications

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“…Our disposal rate of 26.4% was lower than most prior disposal bag studies which reported rates of 55%–95% 32–36 . Several factors likely contribute to this lower rate of disposal.…”

Section: Discussioncontrasting

confidence: 69%

“…Prior studies by our group and others suggest that providing postoperative home‐disposal bags resulted in 55%–95% of patients disposing of their leftover opioids 32–36 . However, a subsequent trial showed disappointing results, with only 14% of patients disposing of their opioids 37 .…”

Section: Introductionmentioning

confidence: 84%

“…Our disposal rate of 26.4% was lower than most prior disposal bag studies which reported rates of 55%-95%. [32][33][34][35][36] Several factors likely contribute to this lower rate of disposal. First, the prior studies were conducted as time-limited trials which allowed for close followup and monitoring by research personnel.…”

Section: Discussionmentioning

confidence: 99%

“…31 Prior studies by our group and others suggest that providing postoperative home-disposal bags resulted in 55%-95% of patients disposing of their leftover opioids. [32][33][34][35][36] However, a subsequent trial showed disappointing results, with only 14% of patients disposing of their opioids. 37 However, no study to date has reported on the feasibility of a pragmatic, low-effort opioid disposal quality improvement intervention implemented outside of a research trial or across an entire health system.…”

Section: Introductionmentioning

confidence: 99%

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Evaluating a health system‐wide opioid disposal intervention distributing home‐disposal bags

Huang,

Bleicher,

Torre

et al. 2023

Health Services Research

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ObjectiveTo evaluate a health system‐wide intervention distributing free home‐disposal bags to surgery patients prescribed opioids.Data Sources and Study SettingWe collected patient surveys and electronic medical record data at an academic health system.Study DesignWe conducted a prospective observational study. The bags were primarily distributed at pharmacies, though pharmacists delivered bags to some patients. The primary outcome was disposal of leftover opioids (effectiveness). Secondary outcomes were patient willingness to dispose and factors associated with disposal (effectiveness), recalling receipt of the bag (reach), and recalling receipt of bags and disposal over time (maintenance). We used a modified Poisson regression to evaluate the relative risk of disposal. Inverse probability of treatment weighting, based on propensity scores, was used to account for differences between survey responders and non‐responders and reduce nonresponse bias.Data Collection/Extraction MethodsFrom August 2020 to May 2021, we surveyed patients 2 weeks after discharge (allowing for home opioid use). Eligibility criteria were age ≥18, English being primary language, valid email address, hospitalization ≤30 days, discharge home, and an opioid prescription sent to a system pharmacy.Principal FindingsWe identified 5134 patients with 2174 completing the survey (response rate 42.3%). Among respondents, 1375 (63.8%) recalled receiving the disposal bag. Among 1075 respondents with leftover opioids, 284 (26.4%) disposed, 552 (51.3%) planned to dispose, 79 (7.4%) did not plan to dispose, 69 (6.4%) had undecided, and 91 (8.5%) had not considered disposal. Recalling receipt of the bag (incidence rate ratio [IRR] 1.25, 95% confidence interval [CI] 1.13–1.37) was positively associated with disposal. Patients who used opioids in the last year were less likely to dispose (IRR 0.82, 95% CI 0.73–0.93). Disposal rates remained stable over the study period while recalling receipt of bags trended up.ConclusionsA pragmatic implementation of a disposal intervention resulted in lower disposal rates than prior trials.

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“…Our disposal rate of 26.4% was lower than most prior disposal bag studies which reported rates of 55%–95% 32–36 . Several factors likely contribute to this lower rate of disposal.…”

Section: Discussioncontrasting

confidence: 69%

Section: Introductionmentioning

confidence: 84%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Evaluating a health system‐wide opioid disposal intervention distributing home‐disposal bags

Huang,

Bleicher,

Torre

et al. 2023

Health Services Research

View full text Add to dashboard Cite

show abstract

“…In the Research Letter titled “Effect of Mailing an At-home Disposal Kit on Unused Opioid Disposal After Surgery: A Randomized Clinical Trial,” 1 published May 6, 2022, Mary Coniglio’s surname was misspelled in the byline and author affiliations. This article has been corrected.…”

mentioning

confidence: 99%

Error in Byline and Affiliations

2023

JAMA Netw Open

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Pharmacist-led interventions in addressing improper disposal practices of unused and expired household medication: A systematic review

Alfian,

Adhinagoro,

Winardi

et al. 2024

Heliyon

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Effect of Mailing an At-home Disposal Kit on Unused Opioid Disposal After Surgery

Abstract: This randomized clinical trial tests the effect of a mailed, at-home disposal kit on disposal rates of unused opioids after surgery.

Cited by 6 publications

References 6 publications

Evaluating a health system‐wide opioid disposal intervention distributing home‐disposal bags

Evaluating a health system‐wide opioid disposal intervention distributing home‐disposal bags

Error in Byline and Affiliations

Pharmacist-led interventions in addressing improper disposal practices of unused and expired household medication: A systematic review

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