Effect of Magnetized Water on Histological Structure of Heart, Lung and Spleen of Albino Rats

Alsaffar, Sura F.; Amer, Nusaibah; Zaki, Lualuaa; Faris, Ali S.; Imran, Natheer Jamal; Nadhim, Zainab F.; Jaafar, Raed I.

doi:10.22401/jnus.16.4.18

Cited by 4 publications

(4 citation statements)

References 30 publications

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“…Our current study displays that nephrotoxicity induced by diabetes could be rescued by the treatment with Ginkgo biloba extract and magnetized water. Likewise, a concomitant reduction in nephrotoxic effects after Ginkgo biloba treatment was mentioned before [ 14 – 16 , 31 – 34 ] as well as magnetized water treatment [ 19 , 21 , 25 – 27 ].…”

Section: Discussionmentioning

confidence: 89%

“…Water was pumped through a flexible tube by a water pump installed inside the unit. The produced magnetic strength was 600 Gauss (measured by a WT10A Tesla meter), which is an average value of the magnetic field strength used in experimental animals and proved to have no pathological effect [ 27 ]. The used magnetic field was uniform and perpendicular to the water flow.…”

Section: Methodsmentioning

confidence: 99%

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Protective Effect of Ginkgo biloba and Magnetized Water on Nephropathy in Induced Type 2 Diabetes in Rat

Zayed

Saleh

Gomaa

et al. 2018

Oxidative Medicine and Cellular Longevity

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We aimed in our current study to explore the protective effect of Ginkgo biloba (GB) and magnetized water (MW) against nephrotoxicity associating induced type 2 diabetes mellitus in rat. Here, we induced diabetes by feeding our lab rats on a high fat-containing diet (4 weeks) and after that injecting them with streptozotocin (STZ). We randomly divided forty rats into four different groups: nontreated control (Ctrl), nontreated diabetic (Diabetic), Diabetic+GB (4-week treatment), and Diabetic+MW (4-week treatment). After the experiment was finished, serum and kidney tissue samples were gathered. Blood levels of glucose, triglycerides, cholesterol, creatinine, and urea were markedly elevated in the diabetic group than in the control group. In all animals treated with GB and MW, the levels of urea, creatinine, and glucose were significantly reduced (all P < 0.01). GB and MW attenuated glomerular and tubular injury as well as the histological score. Furthermore, they normalized the contents of glutathione reductase and SOD2. In summary, our data showed that GB and MW treatment protected type 2 diabetic rat kidneys from nephrotoxic damages by reducing the hyperlipidemia, uremia, oxidative stress, and renal dysfunction.

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Section: Discussionmentioning

confidence: 89%

Section: Methodsmentioning

confidence: 99%

Protective Effect of Ginkgo biloba and Magnetized Water on Nephropathy in Induced Type 2 Diabetes in Rat

Zayed

Saleh

Gomaa

et al. 2018

Oxidative Medicine and Cellular Longevity

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“…Investigations on the histological effects of magnetized water to animals appears to be limited, however, in one study it was shown that rats drinking magnetized water at 0.075 or 0.10 T showed hyperplasia of the lymphoid tissue while the highest tested level of 0.15 T led to necrosis of this tissue (Al‐Saffar et al, ). A possible cause for hyperplasia and necrosis was suggested to be an interference of cellular communication and DNA damage, respectively (Al‐Saffar et al, ; Kamarudin, Sulaiman, & Ismail, ). Another possibility could include compromising the integrity of the cellular membranes.…”

Section: Discussionmentioning

confidence: 99%

Influence of continuous magnetic field exposure on water properties and subsequent effects on the growth performance, plasma biochemistry, nutritive value and liver histopathology of Jade PerchScortum barcooin a recirculating system

et al. 2019

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A 150-days study was conducted on the continuous exposure of magnetized water at 0.00, 0.10, 0.15 and 0.20 Tesla (T) on quadruplicate treatments of Jade Perch Scortum barcoo juveniles in a recirculating system. Each replicate consisted of 18 fish with an average weight of 7.52 g over all treatments. The feeding efficiencies, growth, whole-body proximate plasma parameters, survival were measured and liver histopathology was observed. Our results show no significant improvement in water quality parameters, specific growth rate and body weight gain in this study. However, the best feed conversion ratio was recorded in fish exposed to 0.10, 0.15 and 0.20 T, which are significantly better than the control 0.00 T. Though survival was unaffected but plasma biochemistry and liver histopathology were affected even within the treatment. No liver, plasma or blood abnormalities were detected in fish exposed to 0.10 T and the control 0.00 T. But, one out of four livers from fish in the 0.15 T treatment showed a localized inflammatory response. These changes increased in the liver of fish exposed to 0.20 T, high AST and necrosis in this group is evidence of the liver cells damaged or been at risk. A significantly higher crude protein and lipid were noticed in the exposed fish compared with the control, 0.15 T had the highest crude protein and lipid while the control has the lowest. Based on the overall findings, on growth performance and looking at other factors like absence of any physiological disorder 0.10 T can be used as an effective and affordable technique improve the feeding efficiencies of Jade Perch. K E Y W O R D Scell count, Jade Perch, magnetic device, magnetic field, plasma biochemistry, water quality | INTRODUC TI ONMagnets have been used to improve various water quality parameters in tilapia culture and have been recognized as a new way to enhance some water quality parameters such as mineral solubility by reducing

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“…Water flow was at a relatively low speed (0.34 L/min) to avoid overflow. The 600G is an average strength that has been tested to cause no pathological lesions in experimental rats 26…”

Section: Methodsmentioning

confidence: 99%

<p>Impact of <em>Ginkgo biloba</em> extract and magnetized water on the survival rate and functional capabilities of pancreatic β-cells in type 2 diabetic rat model</p>

Saleh¹,

Anwar²,

Zayed³

et al. 2019

DMSO

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Introduction: Type 2 diabetes (T2D) is a widely distributed disease that affects large population worldwide. This study aimed to verify the role of Ginkgo biloba (GB) extract and magnetized water (MW) on the survival rate and functional capabilities of pancreatic βcells in type 2 diabetic rats. Materials and methods: T2D was induced by feeding the rats on a high-fat diet (20% fat, 45% carbohydrate, 22% protein) for eight weeks followed by intra-peritoneal injection of a single low dose of streptozotocin (25mg/Kg). Forty rats were randomly assigned to four groups (n=10 rats) as follows: non treated control and three diabetic groups. One diabetic group served as a positive control (diabetic), while the other two groups were orally administered with water extract of GB leaves (0.11 g/kg/day) and MW (600 gauss) for four weeks, respectively. Results: The β-cell mass and insulin expression in these cells increased markedly after both treatments, particularly in GB treated group. In addition, the immune-expression of the two antioxidant enzymes; glutathione and superoxide dismutase 2 (SOD2) in the pancreatic tissue demonstrated a down-regulation in GB and MW treated groups as compared with the diabetic group. Conclusion: A four-week treatment of GB and MW protected pancreatic β-cell cells and improved their insulin expression and antioxidant status in type 2 diabetic rats.

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Effect of Magnetized Water on Histological Structure of Heart, Lung and Spleen of Albino Rats

Cited by 4 publications

References 30 publications

Protective Effect of Ginkgo biloba and Magnetized Water on Nephropathy in Induced Type 2 Diabetes in Rat

Protective Effect of Ginkgo biloba and Magnetized Water on Nephropathy in Induced Type 2 Diabetes in Rat

Influence of continuous magnetic field exposure on water properties and subsequent effects on the growth performance, plasma biochemistry, nutritive value and liver histopathology of Jade PerchScortum barcooin a recirculating system

<p>Impact of <em>Ginkgo biloba</em> extract and magnetized water on the survival rate and functional capabilities of pancreatic β-cells in type 2 diabetic rat model</p>

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