Effect of lodophor vs Iodine Tincture Skin Preparation on Blood Culture Contamination Rate

Strand, Calvin L.; Wajsbort, Richard R.; Sturmann, Kai

doi:10.1001/jama.1993.03500080052031

Cited by 111 publications

(42 citation statements)

References 9 publications

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“…Our estimation of bacterial contamination rates of blood donations is higher than those previously reported in whole‐blood units, but consistent with those of the first few ml collected [20] and with blood‐culture contamination rates reported in clinical settings, where the same mechanisms may be implicated [21,22].…”

Section: Discussionsupporting

confidence: 90%

Multivariate analysis of determinants of bacterial contamination of whole‐blood donations

Perez¹,

Bruneau

Chassaigne

et al. 2002

Vox Sanguinis

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Section: Discussionsupporting

confidence: 90%

Multivariate analysis of determinants of bacterial contamination of whole‐blood donations

Perez¹,

Bruneau

Chassaigne

et al. 2002

Vox Sanguinis

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“…The total blood culture contamination rate in National Hospital Abuja was found to be 10.4%, far above the benchmark of 2-3% 7,9,10,11,12. Contamination was relatively more in paediatric patients than in adults, with a total culture per contaminant yield of 9 against 13, and rate of 11% against 8%.…”

Section: Discussionmentioning

confidence: 80%

“…The acceptable blood contamination rate benchmark is 2-3%,7,9,10,11,12 with rates ranging from 1% to 9% 13. Factors associated with blood culture contamination include, but are not limited to, poor technique and procedure used to collect blood, lack of dedicated phlebotomists,8,9,14 improper skin antisepsis 15,16,17.…”

Section: Introductionmentioning

confidence: 99%

Quality assurance in blood culture: A retrospective study of blood culture contamination rate in a tertiary hospital in Nigeria

Chukwuemeka

Samuel

2014

Niger Med J

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Background:Blood culture is a critical tool for diagnosing septicaemia. Quite frequently, contamination of blood sample poses a great challenge to accurate diagnosis. This study evaluated the rate of blood culture contamination in our hospital over a one-year period.Materials and Methods:It was a retrospective study of 1032 blood cultures carried out in a clinical laboratory of a tertiary hospital in North Central part of Nigeria between 2010 and 2011.Results:There were 730 blood cultures from paediatric and 302 adult patients. The overall yield was 22%; 107 out of the 730 were contaminated giving a contamination rate of 10.4%. Contamination rate was higher in children than in adult (11% vs 8%) specimen. These rates were much higher than the acceptable benchmark of 2-3%. The main contaminants were coagulase negative Staphylococcus, Bacillus species, Diphtheroids and Enterococcus species.Conclusion:Contamination rate is high, and mainly due to normal skin flora, suggesting aseptic collection challenges as the main cause. We recommend a review of the entire process of blood collection for culture and analysis with a view to instituting appropriate quality assurance measures to reduce the contamination rate.

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“…Studies have shown that drawing blood cultures from young uncooperative children may influence the rate of contamination 14. A contamination rate of 2% to 3% has been considered acceptable 15. These false positive or contaminant blood cultures may lead to unnecessary diagnostic evaluation and treatment and prolonged hospitalization 16–18.…”

Section: Discussionmentioning

confidence: 99%

Utility of Blood Culture in Uncomplicated Pneumonia in Children

Mendoza-Paredes

Bastos

Leber

et al. 2013

Clin Med Insights Pediatr

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Background:It is believed to be the standard of care to obtain a blood culture in a child who is hospitalized for pneumonia. In recent years, many studies have questioned the utility of this practice in the presence of age appropriate immunization. We conducted this study to determine the current prevalence of bacteremia in children with uncomplicated pneumonia and the utility of obtaining blood cultures in these children.Objective:To evaluate the risk of bacteremia in hospitalized young children with pneumonia.Methods:This was a retrospective review from July 2003 until July 2008. The setting was the pediatric emergency department of an urban teaching hospital. The study population included children under 36 months of age who had been fully immunized and who had been hospitalized with radiographic evidence of uncomplicated pneumonia. Excluded were children who were currently using antibiotics or who had used antibiotics within the previous 48 hours, as well as children with immunodeficiency status such as sickle cell anemia, immunoglobulin deficiency, or children on steroid therapy.The radiologist’s interpretation of each chest radiograph was reviewed and recorded. The variables studied were age (in months), gender, race, birth history, pneumococcal vaccination status, appearance on arrival, temperature on arrival, respiratory rate, oxygen saturation, white blood cell (WBC) count, neutrophil count, band count, and urine culture. The chi-square test and logistic regression were used to analyze the data.Results:A blood culture was obtained in 535 children hospitalized with radiographic pneumonia. Bacteremia was present in 12 children (2.2%). All organisms isolated from the blood cultures were considered contaminants.Conclusion:Children hospitalized with uncomplicated pneumonia have a low rate of positive blood cultures. None of the variables studied predicted bacteremia. The absence of true-positive cultures among the organisms isolated suggests little value in obtaining blood cultures in children hospitalized due to uncomplicated pneumonia.

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Effect of lodophor vs Iodine Tincture Skin Preparation on Blood Culture Contamination Rate

Cited by 111 publications

References 9 publications

Multivariate analysis of determinants of bacterial contamination of whole‐blood donations

Multivariate analysis of determinants of bacterial contamination of whole‐blood donations

Quality assurance in blood culture: A retrospective study of blood culture contamination rate in a tertiary hospital in Nigeria

Utility of Blood Culture in Uncomplicated Pneumonia in Children

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