Effect of levamisole on alkaline phosphatase activity and immunoglobulin secretion of lipopolysaccharide-stimulated murine splenic lymphocytes

Efficient one-pot synthesis of 5-perfluoroalkylpyrazoles by cyclization of hydrazone dianions

“…13 C NMR (75 MHz, CDCl 3 ) δ 156.9, 148.6, 139.4, 132.9 (q, J = 39.0 Hz), 129.8, 129.1, 129.1 (2C), 128.8, 125.8, 125.8, 120.9, 120.6, 120.0 (q, J = 269.0 Hz), 111.3, 110.3 (q, J = 2.5 Hz), 55.5. GC-MS (EI, 70 eV): m/z (%) = 318 (100), 289 (64), 267 (27), 249 (28), 221 (14), 77 (60). HRMS (EI): calcd for C 17 H 13 F 3 N 2 O ([M] + ): 318.09745, found: 318.09699.…”

“…27 Because of a high homology between tissue-specific IAP and TNAP, very few selective inhibitors of IAP have been reported. 28 The tissue specific intestinal alkaline phosphatase is enriched in surfactant-like particles (SLP) and is located at the brush boarder of intestine. It plays an important role in the intestinal absorption of lipids and nutrients through its association with SLP.…”

Enzymatic conversion of magnetic nanoparticles to a non-magnetic precipitate: a new approach to magnetic sensing

“…AP plays an important role in cell cycle, growth, and apoptosis, and research efforts continue to study detection of serum AP as a biomarker. 14 Some conditions, such as rapid bone growth (during puberty), bone disease (Paget's disease or cancer that has spread to the bones), hyperparathyroidism, vitamin D deficiency, or damaged liver cells, result in high blood AP levels. While the detection of AP using fluorescence [15][16][17] and electrochemical 18,19 assays has been studied (Table 1), this report provides the first proof-of-concept of a magnetic assay.…”