Effect of Lentinus edodes polysaccharide on oxidative stress, immunity activity and oral ulceration of rats stimulated by phenol

Yu, Zhenhai; Li, Yin; Yang, Qian; Liu, Yan

doi:10.1016/j.carbpol.2008.07.002

Cited by 72 publications

(37 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore studies by Lim (2011) show that the antiinflammatory response with CV extract correlated with the reduced expression of TNF-α, IL-1β and IL-6 which corresponds to the low secretion of TNF-α obtained in this study. Yu et al (2009) also reported a decrease in levels of serum mucosal interleukin-2 (IL-2) and TNF-α in rats following oral ulceration of Lentinus edodes. Johnson et al (2009) reported that in vivo study of Agaricus blazei reduced the levels of TNF-α by 84% and IL-2 by 46%.…”

Section: Discussionmentioning

confidence: 95%

Effect of a Mushroom (<i>Coriolus versicolor</i>) Based Probiotic on Goat Health

Ekwemalor¹,

Asiamah²,

Adjei‐Fremah³

et al. 2016

American Journal of Animal and Veterinary Sciences

View full text Add to dashboard Cite

Maintenance of an adequate immune response is essential to goat health. CorPet biomass is a mushroom (Coriolus versicolor) based probiotic used as an immune-stimulant in man, horses and small animals. Fifteen BoerXSpanish goats were used in a crossover design to evaluate the effect of a commercial mushroom based probiotic across two periods on resilience of goats to gastrointestinal parasites in pasture based systems. Following initial screening for infection, goats were assigned to three groups of five (n = 15) individuals. Powdered CorPet was soaked in hot or cold water and sterile filtered. Goats were drenched daily with 10 mL of the hot (treatment I) or cold (treatment II) extract daily for an 8 week period. A control group of five age-matched goats received sterile water (treatment III). Body Weight (BW), Fecal Egg Count (FEC), FAMACHA scores, Packed Cell Volume (PCV) and White Blood Cell Differential counts (WBC) were determined weekly. The concentration of total serum protein, 8 Pro-inflammatory cytokines and Prostaglandin (PGE2) secretion was evaluated using commercial ELISAs for each. Treatment had no effect on BW, FEC, FAMACHA scores, PCV and WBC. Total serum protein concentration (p<0.001) increased. Increased levels of interferon production regulator (IFNr), Rantes and Granulocyte-Colony Stimulating Factor (GCSF) and decreased levels of Granulocyte Macrophage ColonyStimulating Factor (GM-CSF) were observed in treated goats. The concentration of PGE2 decreased in all groups over the study period of 8 weeks. Greater changes were observed in treated goats (65-80%) compared to control (50%). Thus in goats CorPet may modulate innate immunity through differential regulation of the secretion of serum proteins including cytokines and PGE2 to impact goat health.

show abstract

Section: Discussionmentioning

confidence: 95%

Effect of a Mushroom (<i>Coriolus versicolor</i>) Based Probiotic on Goat Health

Ekwemalor¹,

Asiamah²,

Adjei‐Fremah³

et al. 2016

American Journal of Animal and Veterinary Sciences

View full text Add to dashboard Cite

show abstract

“…Among these, edible fungi from the genera Ganoderma, Agaricus and Lentinus have been widely investigated (Kües & Liu, 2000;Wasser, 2002), and have also demonstrated some interesting biological properties, such as anti-inflammatory, immunomodulating and antitumor activity (Delmanto et al, 2001;Lin & Zhang, 2004;Yu, Yin, Yang, & Liu, 2009). Also studied has been another genus of edible mushrooms, that of Pholiota Kummer, which, a genus of macrofungi, often endowed with attractive colors, belongs to the family Strophariaceae, order Agaricales, class Basidiomycetes.…”

Section: Introductionmentioning

confidence: 98%

Optimization of process parameters of the Pholiota squarrosa extracellular polysaccharide by Box–Behnken statistical design

Zhao

Wang

2009

Carbohydrate Polymers

View full text Add to dashboard Cite

“…Polysaccharides have been isolated from plants, fungi, yeasts, mushrooms, and sea organisms using extraction (2)(3)(4). A wide range of bioactive polysaccharides isolated from edible fungi of the genera Ganoderma, Agaricus, and Lentinus, have been widely investigated (5,6), and have shown interesting biological properties, such as anti-inflammatory, immunomodulating and antitumor activities (7)(8)(9).…”

Section: Introductionmentioning

confidence: 99%

Chemical characterization and antitumor activity of an exopolysaccharide from Pholiota Squarrosa Quel. AS 5.245

Zhao

Juan

et al. 2015

Food Sci Biotechnol

View full text Add to dashboard Cite

A water-soluble exopolysaccharide (PESP-1) was extracted and purified using DEAE Sephadex A-50 and Sephadex G-100 columns from a submerged culture broth of Pholiota squarrosa Quel. AS 5.245. PEPS-1 was investigated for antitumor activity against Heps tumors implanted in mice. An inhibition rate of 78.46% at a dosage of 100 mg/kg was observed. PEPS-1 significantly (p<0.05) increased the relative spleen/thymus indices of Heps tumor-bearing mice at a dosage of 100 mg/kg, compared with controls. Antitumor properties were probably related to stimulation of the immune response. Preliminary physicochemical analysis identified PEPS-1 as a heteropolysaccharide mainly containing D-mannose, D-glucose and D-galactose at molar ratios of 50:33:18. Small amounts of D-rhamnose and D-xylose were also detected. The average Mw of PEPS-1 was 3.26×10 4 Da. Structural features probably played an important role in the antitumor activity of PEPS-1.

show abstract

Effect of Lentinus edodes polysaccharide on oxidative stress, immunity activity and oral ulceration of rats stimulated by phenol

Cited by 72 publications

References 35 publications

Effect of a Mushroom (<i>Coriolus versicolor</i>) Based Probiotic on Goat Health

Effect of a Mushroom (<i>Coriolus versicolor</i>) Based Probiotic on Goat Health

Optimization of process parameters of the Pholiota squarrosa extracellular polysaccharide by Box–Behnken statistical design

Chemical characterization and antitumor activity of an exopolysaccharide from Pholiota Squarrosa Quel. AS 5.245

Contact Info

Product

Resources

About