1993
DOI: 10.1248/yakushi1947.113.10_718
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Effect of Leaves of Ginkgo biloba on Hair Regrowth in C3H Strain Mice

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Cited by 40 publications
(29 citation statements)
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“…It was discovered that proanthocyanidins extracted from grape seeds promote proliferation of hair follicle cells in vitro and that they possess remarkable haircycle-converting activity from the telogen phase to the anagen phase in vivo (Takahashi et al, 1998). Studies suggested that Ginkgo biloba leaf extract also promotes hair regrowth, through combined effects on proliferation and apoptosis of the cells in the hair follicle, thus suggesting potential as a hair tonic (Kim et al, 1998b;Kobayashi et al, 1993). Other plants such as henna, aloe, rosemary and sage are claimed to have effects on hair growth, but still need more study and clinical trials to substantiate their folk medicine use.…”
Section: Hair Growth Stimulantsmentioning
confidence: 99%
“…It was discovered that proanthocyanidins extracted from grape seeds promote proliferation of hair follicle cells in vitro and that they possess remarkable haircycle-converting activity from the telogen phase to the anagen phase in vivo (Takahashi et al, 1998). Studies suggested that Ginkgo biloba leaf extract also promotes hair regrowth, through combined effects on proliferation and apoptosis of the cells in the hair follicle, thus suggesting potential as a hair tonic (Kim et al, 1998b;Kobayashi et al, 1993). Other plants such as henna, aloe, rosemary and sage are claimed to have effects on hair growth, but still need more study and clinical trials to substantiate their folk medicine use.…”
Section: Hair Growth Stimulantsmentioning
confidence: 99%
“…[14][15][16] However, the polar compound or flavonoids present in ethanolic extract of Z. mauritiana and G. glabra donot possess hair growth promoting activity in testosterone induced or androgenic alopecia.…”
Section: Discussionmentioning
confidence: 99%
“…Based on several studies, flavonoids contribute to the activity of hair growth by strengthening the walls of capillaries in the hair follicles, as well as improve blood circulation to nourish hair follicles that can increase hair growth. [7][8][9] Other studies also shown that flavonoids can shorten the telogen phase and can prolong the anagen phase. Based on research, minoxidil can prolong the anagen phase by extending the dermal papilla cell survival in the hair follicles by increasing proliferation and anti-apoptotic effects that can stimulate hair growth in the anagen phase.…”
Section: Hair Lengthmentioning
confidence: 99%
“…6 Some studies reported that flavonoid demonstrated hair growth promoting activity. 7,8,9 To increase hair growth activity of leaves extracts from N. scutellarium, further fractionation process was needed using the suitable solvent to increase the level of flavonoids, which required in increasing hair growth. Ethyl acetate was chosen as a solvent for a fractionation process of N. scutellarium leaves.…”
Section: Introductionmentioning
confidence: 99%