2008
DOI: 10.1093/bja/aen162
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Effect of landiolol on bispectral index and spectral entropy responses to tracheal intubation during propofol anaesthesia

Abstract: RE increased in response to tracheal intubation, whereas BIS and SE did not. Landiolol and remifentanil suppressed the increase in RE after tracheal intubation with significant inhibition of RE-SE difference.

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Cited by 20 publications
(13 citation statements)
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“…It is well known that landiolol prevented the hypertensive response to tracheal intubation and extubation but did not affect the blood pressure under the preintubation and preextubation conditions (7,11). These studies indicate that landiolol intensely suppressed the enhanced sympathetic nerve function but did not affect the normal sympathetic nerve function (7,11).…”
Section: Discussionmentioning
confidence: 56%
“…It is well known that landiolol prevented the hypertensive response to tracheal intubation and extubation but did not affect the blood pressure under the preintubation and preextubation conditions (7,11). These studies indicate that landiolol intensely suppressed the enhanced sympathetic nerve function but did not affect the normal sympathetic nerve function (7,11).…”
Section: Discussionmentioning
confidence: 56%
“…Menigaux et al 14 em anestesia com propofol e Oda et al 15 em anestesia com sevoflurano (1 CAM) com infusão de esmolol, similar aos opiáceos, descobriram que não houve efeito significativo sobre os valores do BIS antes da intubação traqueal; porém, o aumento dos valores do BIS associados à intubação traqueal e a resposta hemodinâmica e de movimento diminuiram. Kawaguchi et al 34 avaliaram landiolol de ação curta, um antagonista do receptor adrenérgico ␤ 1 , durante condições estáveis de anestesia com propofol, e semelhante ao remifentanil, relataram uma supressão no aumento da entropia de resposta (entropia de resposta = RE e entropia de situação = SE, reflexivas dos níveis nociceptivos e hipnóticos em anestesia geral) à intubação traqueal, na forma de RE nociceptiva e reduções de RE-SE. Em nosso estudo, semelhante a estudos anteriores, 14,15 não houve redução nos valores do BIS na ausência de estímulos dolorosos após a infusão de esmolol e antes da intubação nos três grupos.…”
Section: Discussionunclassified
“…In some studies, noxious pain like tracheal intubation increases spectral entropy, especially RE rather than BIS [12,13], since noxious pain is relevant to increases EMG activity [14]. By comparison, we investigated BIS, RE and SE values during induction of anesthesia, and not in anesthetized patients.…”
Section: Discussionmentioning
confidence: 99%