Effect of lactoferrin supplement on cadmium chloride induced toxicity to male rats: Toxicopathological, ultrastructural and immunological studies

Gad El-Hak, Heba Nageh; Mohamed, Fatma Hashem

doi:10.1016/j.intimp.2023.111182

International Immunopharmacology

2023

DOI: 10.1016/j.intimp.2023.111182

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Effect of lactoferrin supplement on cadmium chloride induced toxicity to male rats: Toxicopathological, ultrastructural and immunological studies

Heba Nageh Gad El-Hak,

Fatma Hashem Mohamed

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2024

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Cited by 2 publications

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Adverse effects of cadmium on lymphoid organs, immune cells, and immunological responses

Kumari,

Nanda,

Firdaus

2024

J of Applied Toxicology

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Humans and animals possess robust immune systems to safeguard against foreign pathogens. However, recent reports suggest a greater incidence of immunity breakdown due to exposure to environmental pollutants, with heavy metals emerging as potential candidates in such immuno‐toxicological studies. While we have extensive data on the general toxicity resulting from exposure to heavy metals, comprehensive documentation of their role as immune disruptors remains scarce. Cd (Cadmium) exerts immunomodulation by interfering with immune organs and cells, leading to altered structure, physiology, and function, thereby inducing symptoms of immune deregulation, inflammation and/or autoimmunity.This review aims to summarize the link between Cd exposure and immune dysfunction, drawing from case studies on exposed human subjects, as well as research conducted on various model organisms and in‐vitro culture systems.

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Adverse effects of cadmium on lymphoid organs, immune cells, and immunological responses

Kumari,

Nanda,

Firdaus

2024

J of Applied Toxicology

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Protective Effects of Lactoferrin Treatment Against Sodium Arsenite Exposure-Induced Nephrotoxicity

Li,

Yin,

Dong

et al. 2024

Biol Trace Elem Res

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Effect of lactoferrin supplement on cadmium chloride induced toxicity to male rats: Toxicopathological, ultrastructural and immunological studies

Cited by 2 publications

References 85 publications

Adverse effects of cadmium on lymphoid organs, immune cells, and immunological responses

Adverse effects of cadmium on lymphoid organs, immune cells, and immunological responses

Protective Effects of Lactoferrin Treatment Against Sodium Arsenite Exposure-Induced Nephrotoxicity

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