Effect of Kombucha tea on chromate(VI)-induced oxidative stress in albino rats

Ram, M. Sai; Anju, B; Pauline, T; Prasad, Dipti; Kain, A. K.; Mongia, Smriti; Sharma, Shivani; Singh, Bhagwat; Singh, R. B.; Ilavazhagan, G.; Kumar, Devendra; Selvamurthy, W.

doi:10.1016/s0378-8741(00)00161-6

Cited by 73 publications

(40 citation statements)

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“…Fermentation was carried out by incubating the Kombucha culture at 28 ± 1°C for 8–10 days. Subsequently, the medium (brew) was centrifuged at 3000 rpm for 30 minutes aseptically and stored in polypropylene vials at -20°C for further use [26]. …”

Section: Methodsmentioning

confidence: 99%

“…Angiogenesis, fibroplasias, complete healing and inflammatory cell infiltration were evaluated in H&E-stained sections and scored semi quantitatively as follows: no or minimal angiogenesis, fibroplasias, complete and inflammatory cell infiltration (-), mild angiogenesis, fibroplasias and complete, inflammatory cell infiltration (+), inflammatory cells form extent and severity /moderate to severe angiogenesis, fibroplasias and complete (++), confluent inflammatory cell aggregates/moderate edema (+++) [26]. …”

Section: Methodsmentioning

confidence: 99%

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RETRACTED ARTICLE: Histopathological and clinical evaluation of Kombucha tea and Nitrofurazone on cutaneous full-thickness wounds healing in rats: an experimental study

et al. 2013

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BackgroundKombucha, a fermented tea (KT) is claimed to possess many beneficial properties. The aim of this study was to evaluate clinical and histopathological alterations of Kombucha tea and Nitrofurazone on cutaneous full-thickness wounds healing in rat.MethodsIn present study 24 Wister -albino rats weighing 150–200 g were selected and divided to two treatment groups as Nitrofurazone ointment (0.2%) and Kombucha tea. Subsequently, the anesthesia was exerted by Ketamin hydrochloride 10% (40 mg/kg) and Xylasine (2 mg/kg) through intra muscular (IM) route. Furthermore, upon preparation of dorsal region of the animal for surgery, a piece of full-thickness skin removed (2 × 2 cm). In order to comparing wounds healing clinically and histologically, once every four days from the commencement, the wounds were photographed and the healed surface was measured by Scion image software.ResultThe clinical findings indicated that the Kombucha fungus resulted in precipitating healing than Nitrofurazone; however, it was not significant (p > 0.05). In order to pathological comparing of wound healing process, several wound biopsies were taken on 4, 8, 12, 16 and 20th days. Additionally, the histopathological results demonstrated that there was inflammation in Nitrofurazone group through twelveth day, somehow the epithelium was formed and abundant vessels were visible. Although on 16th day and the previous days the healing condition of Kombucha fungus was considered as minimal rate, revealing it is similar to Nitrofurazone group on 20th day.ConclusionsTo wrap up. These observations suggest that the Kombucha fungus healing quality was rapid from 12th day to the end of the research, whereas no significant difference was observed.Virtual slideThe virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1107407136102196

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

RETRACTED ARTICLE: Histopathological and clinical evaluation of Kombucha tea and Nitrofurazone on cutaneous full-thickness wounds healing in rats: an experimental study

et al. 2013

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“…Cytotoxicity was studied by using neutral red uptake (Sairam et al, 2000), a supra-vital dye, that is selectively taken by the live cells. Briefly, 10 ll of neutral red dye (0.1%) was added to the cells and incubated at 37°C in CO 2 incubator for 45 min.…”

Section: Hplc Analysismentioning

confidence: 99%

Subcritical water extraction of antioxidant compounds from Seabuckthorn (Hippophae rhamnoides) leaves for the comparative evaluation of antioxidant activity

et al. 2011

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“…However, only a few experimental investigations have demonstrated these mentioned properties. Indeed, recent studies have reported that Kombucha prevents the paracetamol induced hepatotoxicity (Pauline et al, 2001) and the chromate (VI) induced oxidative stress (Sai Ram et al, 2000). Moreover, regular Kombucha tea ingestion contributes significantly to weight gain inhibition and life elongation (Hartmann, Burleson, Holmes, & Geist, 2000).…”

Section: Introductionmentioning

confidence: 99%