Background: Kangaroo mother care could be a key procedure to decrease neonatal mortality and morbidity of preterm and low-birth-weight neonates. However, in Ethiopia, preterm birth and low-birth-weight neonatal death still exist. This study aimed to determine the pooled prevalence of knowledge, Attitude, and practice of kangaroo mother care among postnatal women in Ethiopia.Methods: PubMed, Web of Science, Google Scholar, EMBASE, manual search, and Ethiopian University online library were searched. The data were extracted by using Microsoft excel and analyzed by STATA version 11 statistical software. The Publication bias was checked by funnel and more objectively through Egger's test and Begg’s test with P < 0.05 considered being a potential publication for bias. I2 was used to check for the presence of heterogeneity of the studies. Overall estimated analysis was done. Subgroup analysis was done by region, study setting, publications, gestational age, birth weight, and the component of kangaroo care. Sensitivity analysis was conducted to see the effect of a single study on the pooled estimation.Results: A total of 5 studies with 1,232 respondents for knowledge, five studies with 1,232 respondents for attitude, and 16 studies with 12,475 respondents for practice were used to estimate the pooled level of good knowledge, positive attitude, and poor practice of kangaroo mother care among postnatal women. The pooled estimate of good knowledge, positive attitude and poor practice of kangaroo mother care was found to be 64.62% (95% CI: 47.15%-82.09%; I2 = 97.8%), 61.55 % (49.73-73.38%; I2 =94.8%) and 45.7% (95%CI: 37.297-54.092%; I2 = 98.5%) respectively.Conclusion: Findings showed significant gaps in kangaroo mother care-related knowledge, attitude, and practice compared with reported results of developed countries of the demographic health survey. Therefore, it is better to have periodic training and counseling on kangaroo mother care for postnatal women.