Effect of juvenile hormone on the central nervous processing of sex pheromone in an insect

Anton, Sylvia; Gadenne, Christophe

doi:10.1073/pnas.96.10.5764

Cited by 98 publications

(84 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The general response pattern was similar to that observed previously; neurons responded generally with an excitatory response, characterized by a fast increase in AP frequency, followed by an inhibitory period devoid of APs (Anton and Gadenne, 1999;Gadenne and Anton, 2000;Jarriault et al, 2009b). In virgin males (N=60, 33, and 38 neurons for NaCl-, OA-and 5-HT-injected males, respectively), there was no statistical difference in AL neuron response threshold between NaCl-injected males, and OA-and 5-HT-injected males (G=1.2, P>0.05); all males showed a high proportion of very sensitive neurons (with a low response threshold) (Fig.…”

Section: Effects Of Oa and 5-ht On Al Neuron Sensitivity To Sex Pherosupporting

confidence: 84%

“…Our results showed that both OA and 5-HT had no effect on the response threshold of AL neurons of virgin males to pheromone, presumably because the AL sensitivity of mature virgin 5-day-old males is already at its maximum, as compared with the low AL sensitivity of immature 1-day-old males or newly mated males, where sensitivity can be increased by amine injection (Anton and Gadenne, 1999;Gadenne et al, 2001;Jarriault et al, 2009a). However, OA induced changes in all four AL neuron response characteristics analyzed here whereas 5-HT only changed the response latency to sex pheromone.…”

Section: Oa and 5-ht Modulate Sex Pheromone Response Characteristics mentioning

confidence: 53%

“…In this species, there is an age-and juvenile hormone (JH)-dependent maturation of both behavioural and central nervous responses to the female-produced sex pheromone (Anton and Gadenne, 1999;Gadenne et al, 1993). JH was also shown to control the development of the sex accessory glands (SAGs) in this species.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Mating-induced transient inhibition of responses to sex pheromone in a male moth is not mediated by octopamine or serotonin

Barrozo¹,

Jarriault²,

Simeone³

et al. 2010

Journal of Experimental Biology

Self Cite

View full text Add to dashboard Cite

SUMMARYIn the male moth, Agrotis ipsilon, mating induces a transient inhibition of behavioural and central nervous responses to sex pheromone. Newly mated males are not attracted to sex pheromone, and the sensitivity of their antennal lobe (AL) neurons is lower than in virgin males. This rapid transient olfactory inhibition prevents them from re-mating unsuccessfully until they have refilled their sex glands. We hypothesized that this olfactory 'switch off' might be controlled by neuromodulators such as biogenic amines. To test our hypothesis, we studied the effects of octopamine (OA) and serotonin (5-hydroxytryptamine, 5-HT) on the coding properties of pheromone-sensitive AL neurons in virgin and newly mated males. We show that AL neuron sensitivity increased in newly mated males after injection of OA or 5-HT, but only OA treatment affected certain response characteristics of AL neurons in virgin males. Whereas all measured AL neuron response characteristics were different between virgin and newly mated males, amine treatment in newly mated males restored only the latency and spike frequency, but not the duration of excitatory and inhibitory phases, which were initially found in virgin males. Additionally, we investigated the behavioural effects of OA and 5-HT treatments in virgin and mated males. Although OA and 5-HT enhanced the general flight activity of newly mated males, amine treatments did not restore the behavioural pheromone response of mated moths. Altogether, these results show that, although biogenic amines modulate the olfactory system in moths, OA and 5-HT are probably not involved in the post-mating inhibition of responses to sex pheromone in A. ipsilon males.

show abstract

Section: Effects Of Oa and 5-ht On Al Neuron Sensitivity To Sex Pherosupporting

confidence: 84%

Section: Oa and 5-ht Modulate Sex Pheromone Response Characteristics mentioning

confidence: 53%

See 1 more Smart Citation

Mating-induced transient inhibition of responses to sex pheromone in a male moth is not mediated by octopamine or serotonin

Barrozo¹,

Jarriault²,

Simeone³

et al. 2010

Journal of Experimental Biology

Self Cite

View full text Add to dashboard Cite

show abstract

“…This adult volume gain can be induced up to a critical age by specific odors and, unlike pupal growth, seems to involve a cAMPdependent signalling pathway (Devaud et al 2001). In Agrotis ipsilon pheromone-specific odor processing seems to be dependent upon juvenile hormone and age (Anton and Gadenne 1999;Gadenne and Anton 2000;Greiner et al 2002). Two main possibilities may explain the induction of adult neuropilar growth: first, it might represent the final maturation processes, which are possibly hormonally controlled, or second, it might be a manifestation of early adult neural plasticity depending on sensory input (as discussed in Julian and Gronenberg 2002).…”

Section: Discussionmentioning

confidence: 99%

Standard three-dimensional glomeruli of the Manduca sexta antennal lobe: a tool to study both developmental and adult neuronal plasticity

Huetteroth

Schachtner

2005

Cell Tissue Res

View full text Add to dashboard Cite

The metamorphosing antennal lobe (AL) of the sphinx moth Manduca sexta serves as an established model system for studying neuronal development. To improve our understanding of mechanisms involved in neuronal plasticity, we have analyzed the size, shape, and localization of ten identified glomeruli at three different time points during development and in the adult, viz., (1) 13 days after pupal eclosion (P13), which reflects a time when the basic glomerular map has formed, (2) immediately after adult eclosion (A0), which represents a time when the newly formed glomeruli are uninfluenced by external odors, and (3) 4 days after adult eclosion (A4), which reflects a time when the animals have been exposed to surrounding odors. Our data from normally developing ALs of male M. sexta from P13 to A0 revealed an increase in size of all examined glomeruli of between 40% and 130%, with the strongest increases occurring in two of the three sex-specific glomeruli (cumulus, toroid). From A0 to A4, the cumulus and toroid increased significantly when correlated to AL volume, whereas the other glomeruli reached the sizes gained after A0. This study was based on antibody staining against the ubiquitous synaptic vesicle protein synaptotagmin, confocal laser scan microscopy, and the three-dimensional (3D) analysis tool AMIRA. Tissue permeability and therefore reliability of the staining quality was enhanced by using formalin/methanol fixation. The standard 3D glomeruli introduced in this study can now be used as basic tools for further examination of neuronal plasticity at the level of the identified neuropil structures, viz., the glomeruli of the AL of M. sexta.

show abstract

“…It is mainly known for its role in metamorphosis, reproduction and more recently longevity (Flatt et al, 2005). Interestingly, JH has been shown to modulate olfactory interneuron sensitivity to pheromones in locust (Anton and Gadenne, 1999). In honeybees, high JH levels are also known to increase foraging activity (Robinson, 1985), whereas it lowers the sensitivity threshold to sugar (Pankiw and Page, Jr, 2003).…”

Section: Why Do To 1 Flies Die Faster Than Wt During Starvation?mentioning

confidence: 99%

Regulation of feeding behaviour and locomotor activity bytakeoutinDrosophila

Meunier

Belgacem

Martin

2007

Journal of Experimental Biology

129

143

View full text Add to dashboard Cite

SUMMARY The hormonal regulation of feeding behaviour is well known in vertebrates,whereas it remains poorly understood in insects. Here, we report that the takeout gene is an essential component of nutritional homeostasis in Drosophila. takeout encodes a putative juvenile hormone (JH)binding protein and has been described as a link between circadian rhythm and feeding behaviour. However, the physiological role of takeout and its putative link to JH remain unknown. In this study, we show that takeout (to1) flies failed to adapt their food intake according to food availability and that most defects could be genetically rescued. When food is abundant, to1 are hyperphagic, yielding to hypertrophy of the fat body. When food reappears after a starvation period, to1 flies do not increase their food intake as much as wild-type flies. This defect in food intake regulation is partly based on the action of Takeout on taste neurons, because the sensitivity of to1 gustatory neurons to sugars does not increase after starvation, as in wild-type neurons. This lack of regulation is also evident at the locomotor activity, which normally increases during starvation, a behaviour related to food foraging. In addition, to1 flies lack sexual dimorphism of locomotor activity,which has previously been linked to the JH circulating level. Moreover,application of the JH analog methoprene rescues the phenotype. These results suggest that takeout plays a central role as a feeding regulator and may act by modulating the circulating JH level.

show abstract

Effect of juvenile hormone on the central nervous processing of sex pheromone in an insect

Cited by 98 publications

References 28 publications

Mating-induced transient inhibition of responses to sex pheromone in a male moth is not mediated by octopamine or serotonin

Mating-induced transient inhibition of responses to sex pheromone in a male moth is not mediated by octopamine or serotonin

Standard three-dimensional glomeruli of the Manduca sexta antennal lobe: a tool to study both developmental and adult neuronal plasticity

Regulation of feeding behaviour and locomotor activity bytakeoutinDrosophila

Contact Info

Product

Resources

About