“…Ischemic preconditioning (IPC) is an intrinsic process whereby repeated short episodes of ischemia protect the organ against a subsequent prolonged ischemic insult [4][5][6][7] . Several reports have described the effects of IPC on the reduction of apoptosis of epithelial cells 4,5,[7][8][9] , structural protection 4,10,11 and preservation of intestinal contractility 10 . In brief, the IPC stimulus, made up of cycles of brief ischemia and reperfusion, initiates production of a number of autacoids (such as acetylcholine, adenosine, bradykinin, endothelin, and opioids) 11 .…”