Effect of iron supplementation on maximal oxygen uptake in female athletes

Radjen, Slavica; Radjen, Goran; Zivotić-Vanović, M; Radaković, Sonja; Vasiljević, Nadja; Stojanovic, D.

doi:10.2298/vsp1102130r

Cited by 19 publications

(21 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Of the 45 athletes screened, 15 (nine female athletes: age, 21 T 2 yr; height, 169.1 T 4.0 cm; body mass, 59.3 T 4.3 kg; V O 2max , 64.5 T 5.7 mLIkg j1 Imin j1 ; and six male athletes: age, 20 T 1 yr; height, 178.8 T 5.9 cm; body mass, 65.2 T 3.5 kg; V O 2max , 76.7 T 2.7 mLIkg j1 Imin j1 ) were classified as irondeficient but not anemic (females: sFer G 30.0 KgIL j1 , Hb 9 12.0 gIdL j1 ; males: sFer G 40 KgIL j1 , Hb 9 12.0 gIdL j1 ). It is acknowledged that there is no universal consensus for the classification of IDNA in athlete populations, with a variety of cutoffs for sFer appearing in the literature (3,9,29). An upper limit of 40 KgIL j1 is used in the present investigation for male athletes because this is considered iron deficient by the national governing body for track and field to which the athletes are affiliated with and whereby medical practitioners would treat and monitor the iron status of each athlete.…”

Section: Methodsmentioning

confidence: 99%

Effect of Intravenous Iron on Aerobic Capacity and Iron Metabolism in Elite Athletes

Burden

Pollock

Whyte

et al. 2015

Medicine &Amp; Science in Sports &Amp; Exercise

View full text Add to dashboard Cite

show abstract

Section: Methodsmentioning

confidence: 99%

Effect of Intravenous Iron on Aerobic Capacity and Iron Metabolism in Elite Athletes

Burden

Pollock

Whyte

et al. 2015

Medicine &Amp; Science in Sports &Amp; Exercise

View full text Add to dashboard Cite

show abstract

“…16 Some (but not all) RCTs have shown that iron improves aerobic 17 and endurance capacity, 18 cognitive performance, 19 productivity, 20 symptomatic fatigue, 21 and mood 22 in iron-depleted nonanemic women.…”

Section: Effects Of Iron Supplementation In Nonpregnant Womenmentioning

confidence: 99%

Control of iron deficiency anemia in low- and middle-income countries

Pasricha

Drakesmith

Black

et al. 2013

Blood

354

297

View full text Add to dashboard Cite

Despite worldwide economic and scientific development, more than a quarter of the world’s population remains anemic, and about half of this burden is a result of iron deficiency anemia (IDA). IDA is most prevalent among preschool children and women. Among women, iron supplementation improves physical and cognitive performance, work productivity, and well-being, and iron during pregnancy improves maternal, neonatal, infant, and even long-term child outcomes. Among children, iron may improve cognitive, psychomotor, and physical development, but the evidence for this is more limited. Strategies to control IDA include daily and intermittent iron supplementation, home fortification with micronutrient powders, fortification of staple foods and condiments, and activities to improve food security and dietary diversity. The safety of routine iron supplementation in settings where infectious diseases, particularly malaria, are endemic remains uncertain. The World Health Organization is revising global guidelines for controlling IDA. Implementation of anemia control programs in developing countries requires careful baseline epidemiologic evaluation, selection of appropriate interventions that suit the population, and ongoing monitoring to ensure safety and effectiveness. This review provides an overview and an approach for the implementation of public health interventions for controlling IDA in low- and middle-income countries, with an emphasis on current evidence-based recommendations.

show abstract

“…3). When the 20 anemic participants from the single trial recruiting iron-deficient anemic women (30) were removed from the analysis, the beneficial effect from iron remained significant [MD: 2.18 (95% CI: 0.57, 3.79), P = 0.008, I 2 = 72%], as it did when the 1 trial that recruited 42% male participants (31) was excluded [MD: 2.25 (95% CI: 0.70, 3.80)]. The effect was seen in irondeficient women, although there was also a benefit in women for whom iron status had not been determined at recruitment.…”

Section: Maximal Exercise Performancementioning

confidence: 99%

Iron Supplementation Benefits Physical Performance in Women of Reproductive Age: A Systematic Review and Meta-Analysis

Pasricha

Löw

Thompson

et al. 2014

The Journal of Nutrition

136

113

View full text Add to dashboard Cite

Animal and human observational studies suggest that iron deficiency impairs physical exercise performance, but findings from randomized trials on the effects of iron are equivocal. Iron deficiency and anemia are especially common in women of reproductive age (WRA). Clear evidence of benefit from iron supplementation would inform clinical and public health guidelines. Therefore, we performed a systematic review and meta-analysis to determine the effect of iron supplementation compared with control on exercise performance in WRA. We searched the Cochrane Central Register of Clinical Trials, MEDLINE, Scopus (comprising Embase and MEDLINE), WHO regional databases, and other sources in July 2013.Randomized controlled trials that measured exercise outcomes in WRA randomized to daily oral iron supplementation vs.control were eligible. Random-effects meta-analysis was used to calculate mean differences (MDs) and standardized MDs (SMDs). Risk of bias was assessed using the Cochrane risk-of-bias tool. Of 6757 titles screened, 24 eligible studies were identified, 22 of which contained extractable data. Only 3 studies were at overall low risk of bias. Iron supplementation improved both maximal exercise performance, demonstrated by an increase in maximal oxygen consumption (VO 2 max) [for relative VO 2 max, MD: 2.35 mL/(kg Á min); 95% CI: 0.82, 3.88; P = 0.003, 18 studies; for absolute VO 2 max, MD: 0.11 L/min; 95% CI: 0.03, 0.20; P = 0.01, 9 studies; for overall VO 2 max, SMD: 0.37; 95% CI: 0.11, 0.62; P = 0.005, 20 studies], and submaximal exercise performance, demonstrated by a lower heart rate (MD: 24.05 beats per minute; 95% CI: 27.25, 20.85; P = 0.01, 6 studies) and proportion of VO 2 max (MD: 22.68%; 95% CI: 24.94, 20.41; P = 0.02, 6 studies) required to achieve defined workloads. Daily iron supplementation significantly improves maximal and submaximal exercise performance in WRA, providing a rationale to prevent and treat iron deficiency in this group. This trial was registered with PROSPERO (http://www. crd.york.ac.uk/PROSPERO/prospero.asp) as CRD42013005166. J. Nutr. 144: 906-914, 2014.

show abstract

Effect of iron supplementation on maximal oxygen uptake in female athletes

Cited by 19 publications

References 31 publications

Effect of Intravenous Iron on Aerobic Capacity and Iron Metabolism in Elite Athletes

Effect of Intravenous Iron on Aerobic Capacity and Iron Metabolism in Elite Athletes

Control of iron deficiency anemia in low- and middle-income countries

Iron Supplementation Benefits Physical Performance in Women of Reproductive Age: A Systematic Review and Meta-Analysis

Contact Info

Product

Resources

About