Effect of Iron, Aluminum and Zinc (as Anoda) on Metformin Deconcentration and Aspirin Deconcentration with Electrolysis Method

Abstract

Aspirin and metformin are drugs that function as an analgesic-antiseptic, antiinflammatory, and antiplatet. Ferrous metal, aluminum metal and zinc metal are easily found and often used by the public. This study aims to reduce the two drugs by electrolysis method, using three different metals, namely iron metal, aluminum metal and zinc metal as an anode. The success of the electrolysis process was seen with a decrease in the sample COD index. In situations without the addition of electrolytes using ferrous metals, aluminum metals and zinc metals the COD index decreases in the sample very low (10-15%). This study aims to increase the success of the electrolysis process, by adding various types of electrolytes, such as acetic acid (weak electrolytes), sodium chloride (strong electrolytes), sodium chloride and fenton reagents. The addition of electrolytes can significantly increase electrolysis results. Interactions between drugs during electrolysis are tracked with possible changes in the chromophore group (with UV-Visible spectrum) and functional groups (with FTIR spectrum) of the sample. From the research data obtained information that there is a decrease and shift in the UV-Visible spectrum and changes in the functional group after the electrolysis process occurs. The electrolysis process of Metformin and Aspirin occurs optimally at a distance of 1 cM (in iron, aluminum and zinc as an anode and carbon as an anode) and a processing time of 30 minutes. The voltage used in the electrolysis process of Metformin is optimal at 3 volts and 9 volts in the Aspirin electrolysis process (in iron and aluminum as an anode and carbon as an anode). The best electrolysis percentage is obtained, after adding NaCl solution and Fenton's reagent in the range of 65-70%.