Effect of Intravenous Magnesium Sulphate on Cardiovascular Responses During Tracheal Extubation in Patient Undergoing Craniotomies

Goyal, Shikha; Shrivastava, Sourabh

doi:10.14260/jemds/2017/729

Cited by 3 publications

(5 citation statements)

References 20 publications

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“…The evaluated studies included data from 4303 people. 2300 of them magnesium (1114 by IV in 35 studies [6,), by epidural in 12 studies [47][48][49][50][51][52][53][54][55][56][57][58], 638 by intraperitoneal injection in 16 studies [59][60][61][62][63][64][65][66][67][68][69][70][71][72][73][74] and 108 by Other routes received 4 interventions. All studies compared magnesium sulfate with placebo or no drug.…”

Section: Resultsmentioning

confidence: 99%

Investigating the Effect of Magnesium in Preventing Tremors after Anesthesia: A Systematic Review

Esmailpour Roshan,

Jafari

2024

Asian Pac J Cancer Biol

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Background and Purpose: In addition, magnesium is prescribed intravenously, epidurally, or intraperitoneally, each of which may have different effects depending on the surgical procedure. In this review, we searched for randomized clinical trials that compared preoperative magnesium administration with controls and included studies that assessed chills as a primary and possible outcome. change. The main objective of this study was to evaluate the effect of preoperative magnesium in the prevention of postoperative chills. Materials and methods: This article is a systematic review that searched for all quality articles published in the Cochrane database until the end of 2020. References were checked, PubMed and Web of Science 55,555. Results: The initial search identified 3,294 publications. 64 articles were included in this study. The results showed that the frequency of colds in the group receiving intravenous, epidural and intraperitoneal magnesium was significantly reduced compared to the control group. Conclusion: Prophylactic use of magnesium can reduce the severity and number of post-anesthetic chills and other post-anesthetic symptoms.

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Section: Resultsmentioning

confidence: 99%

Investigating the Effect of Magnesium in Preventing Tremors after Anesthesia: A Systematic Review

Esmailpour Roshan,

Jafari

2024

Asian Pac J Cancer Biol

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“…The scope of our evaluation encompassed a significant volume of data from a total of 4303 individuals. Among them, 2300 individuals received magnesium through various routes, including 1114 participants who received intravenous magnesium in 35 studies [ 10 , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] , [35] , [36] , [37] , [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , [46] , [47] , [48] , [49] , [50] ], 12 studies that administered magnesium epidurally [ [51] , [52] , [53] , [54] , [55] , [56] , [57] , [58] , [59] , [60] , [61] , [62] ] to a total of 638 participants, and 16 studies that utilized intraperitoneal injection to deliver magnesium to 638 individuals [ [63] , [64] , [65] , [66] , [67] , [68] , [69] , [70] , [71] , [72] , [73] , [74] , [75] , [76] , [77] , [78] ]. Additionally, 108 participants received magnesium through alter...…”

Section: Resultsmentioning

confidence: 99%

“…In this study, a total of 54 clinical trials were analyzed [ [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] , [35] , [36] , [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , [46] , [47] , [48] , [49] , [50] , [51] , [52] , [53] , [54] , [55] , [56] , [57] , [58] , [59] , [60] , [61] , [62] , [65] , [66] , [67] , [68] , [69] , 72 , 73 , 77 , 82 , 83 ], and the incidence of shivering was analyzed in different groups based on the method of magnesium administration. The results revealed that the incidence of shivering was lower in the group that received magnesium via IV injection compared to the control group.…”

Section: Resultsmentioning

confidence: 99%

“…The scientific text reports that 36 studies [ [19] , [20] , [21] , [22] , [23] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , 35 , 36 , [39] , [40] , [41] , [42] , [44] , [45] , [46] , [47] , [49] , [50] , [51] , [52] , [54] , [55] , [56] , [57] , [58] , [59] , [60] ] were conducted to examine the occurrence of a blood pressure drop, and the overall incidence rate was found to be similar across all studies. The hazard ratio was 0.91, with a confidence interval of 0.79–1.01, and I 2 = 2 %.…”

Section: Resultsmentioning

confidence: 99%

“…There have been 32 investigations [ 11 , 19 , 22 , 26 , 27 , 29 , [31] , [32] , [33] , 39 , 40 , 42 , 44 , 47 , [49] , [50] , [51] , [52] , [53] , [54] , [55] , [56] , [57] , [58] , [59] , [60] , [61] , [62] , 66 , 67 , 73 , 77 ] that have documented bradycardia. Neither the overall incidence, which had a hazard ratio of 0.85 and a 95 % confidence interval ranging from 0.08 to 0.66, nor the subgroup analysis conducted in accordance with the prescription method, revealed any differences.…”

Section: Resultsmentioning

confidence: 99%

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The impact of magnesium on shivering incidence in cardiac surgery patients: A systematic review

Ding,

Wang,

Ghorbani

et al. 2024

Heliyon

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Effectiveness of Magnesium in Preventing Shivering in Surgical Patients: A Systematic Review and Meta-analysis

Kawakami¹,

Nakajima

Mihara

et al. 2019

Anesthesia &Amp; Analgesia

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BACKGROUND: Clinical trials regarding the antishivering effect of perioperative magnesium have produced inconsistent results. We conducted a systematic review and meta-analysis with Trial Sequential Analysis to evaluate the effect of perioperative magnesium on prevention of shivering. METHODS: We searched PubMed, EMBASE, Web of Science, Cochrane Central Register of Controlled Trials, and 2 registry sites for randomized clinical trials that compared the administration of magnesium to a placebo or no treatment in patients undergoing surgeries. The primary outcome of this meta-analysis was the incidence of shivering. The incidence of shivering was combined as a risk ratio with 95% CI using a random-effect model. The effect of the route of administration was evaluated in a subgroup analysis, and Trial Sequential Analysis with a risk of type 1 error of 5% and power of 90% was performed. The quality of each included trial was evaluated, and the quality of evidence was assessed using the Grading of Recommendation Assessment, Development, and Evaluation approach. We also assessed adverse events. RESULTS: Sixty-four trials and 4303 patients (2300 and 2003 patients in magnesium and control groups, respectively) were included. The overall incidence of shivering was 9.9% in the magnesium group and 23.0% in the control group (risk ratio, 0.42; 95% CI, 0.33–0.52). Subgroup analysis revealed that the incidence of shivering was lower with IV (risk ratio, 0.29; 95% CI, 0.29–0.54; Grading of Recommendation Assessment, Development, and Evaluation, moderate), epidural (risk ratio, 0.24; 95% CI, 0.13–0.43; Grading of Recommendation Assessment, Development, and Evaluation, low), and intrathecal administration (risk ratio, 0.64; 95% CI, 0.43–0.96; Grading of Recommendation Assessment, Development, and Evaluation, moderate). Only trials with low risk of bias were included for Trial Sequential Analysis. The Z-cumulative curve for IV magnesium crossed the Trial Sequential Analysis monitoring boundary for benefit even though only 34.9% of the target sample size had been reached. The Z-cumulative curve for epidural or intrathecal administration did not cross the Trial Sequential Analysis monitoring boundary for benefit. No increase in adverse events was reported. CONCLUSIONS: Perioperative IV administration of magnesium effectively reduced shivering and Trial Sequential Analysis suggested that no more trials are required to confirm that IV magnesium effectively reduces shivering.

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Effect of Intravenous Magnesium Sulphate on Cardiovascular Responses During Tracheal Extubation in Patient Undergoing Craniotomies

Cited by 3 publications

References 20 publications

Investigating the Effect of Magnesium in Preventing Tremors after Anesthesia: A Systematic Review

Investigating the Effect of Magnesium in Preventing Tremors after Anesthesia: A Systematic Review

The impact of magnesium on shivering incidence in cardiac surgery patients: A systematic review

Effectiveness of Magnesium in Preventing Shivering in Surgical Patients: A Systematic Review and Meta-analysis

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