Effect of intravenous lidocaine on isoflurane MAC in dogs

Valverde, Alexander; Tj, Doherty; Hernández, Jorge A.; Davies, Wendy

doi:10.1046/j.1467-2995.2003.00133_11.x

Cited by 8 publications

(25 citation statements)

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“…2002). In dogs, systemic doses of lidocaine, approximately twice of those reported in the current study, reduced minimum alveolar concentration (MAC) of isoflurane by 18.7% (Valverde et al. 2002).…”

Section: Introductionmentioning

confidence: 54%

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Systemic lidocaine infusion as an analgesic for intraocular surgery in dogs: a pilot study

Smith

Bentley

Shih

et al. 2004

Veterinary Anaesthesia and Analgesia

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Section: Introductionmentioning

confidence: 54%

“…2002). Animal studies have documented an effect of systemic lidocaine on inhalant anesthetic requirement (Doherty & Frazier 1998; Valverde et al. 2002).…”

Section: Introductionmentioning

confidence: 99%

Systemic lidocaine infusion as an analgesic for intraocular surgery in dogs: a pilot study

Smith

Bentley

Shih

et al. 2004

Veterinary Anaesthesia and Analgesia

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“…However, when compared with results from other species, the reduction in MAC (18.3%) was less then expected. In dogs, a lower infusion rate of L (50 μ g kg −1 minute −1 ) reduced the ISO MAC by 18.7% in one study (Valverde et al. 2004) and by 29% in another (Muir et al.…”

Section: Discussionmentioning

confidence: 96%

“…Intravenous L reduced the minimum alveolar concentration (MAC) of isoflurane (ISO) in dogs (Muir et al. 2003; Valverde et al. 2004), cats (Pypendop & Ilkiw 2005), and horses (Dzikiti et al.…”

Section: Introductionmentioning

confidence: 99%

Effect of intravenous lidocaine and ketamine on the minimum alveolar concentration of isoflurane in goats

Doherty

Redua

Queiroz-Castro

et al. 2007

Veterinary Anaesthesia and Analgesia

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“…Additionally, several studies have shown that lidocaine infusion reduces the minimum alveolar concentration (MAC) of inhalation agents in horses 15 , dogs [16][17][18][19] , goats 20 , cats 21 and calves 22 .…”

Section: Introductionmentioning

confidence: 99%

Analgesic comparison of systemic lidocaine, morphine or lidocaine plus morphine infusion in dogs undergoing fracture repair

et al. 2014

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Intellectual and scientific content of the study, statistical analysis, critical revision. ABSTRACT PURPOSE:To compare the postoperative analgesic effects of lidocaine, morphine and lidocaine plus morphine administered by constant rate infusion (CRI) and analyzing their effects on opioid requirements after orthopedic surgery in dogs. METHODS:Twenty-four dogs underwent fracture repairs were premedicated with IM acepromazine (0.05 mg/kg) combined with morphine (0.3mg/kg). Anesthesia was induced with IV propofol (4 to 5 mg/ kg) and maintained with isoflurane. The dogs were randomly assigned to 3 groups and administered a CRI IV of lidocaine (T-L), morphine (T-M) or lidocaine plus morphine (T-LM) at the same doses. Postoperative analgesia was assessed for 24 hours using a Visual Analog Scale (VAS) and the Glasgow Composite Pain Scale (GCPS). Rescue analgesia was performed if the evaluation score exceeded 50% of the VAS and/or 33% of the GCPS. RESULTS:The pain score and postoperative opioid requirements did not differ among the treatments. Rescue analgesia was administered to 1/8 dogs in the T-M and T-LM, and to 3/8 dogs in the T-L. CONCLUSION:Lidocaine, morphine or lidocaine/morphine CRI may be efficacious techniques for pain management in the first 24 hours post-surgery. However, the two drugs administered together did not reduce the postoperative opioid requirement in dogs undergoing fracture repair.

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Effect of intravenous lidocaine on isoflurane MAC in dogs

Cited by 8 publications

References 0 publications

Systemic lidocaine infusion as an analgesic for intraocular surgery in dogs: a pilot study

Systemic lidocaine infusion as an analgesic for intraocular surgery in dogs: a pilot study

Effect of intravenous lidocaine and ketamine on the minimum alveolar concentration of isoflurane in goats

Analgesic comparison of systemic lidocaine, morphine or lidocaine plus morphine infusion in dogs undergoing fracture repair

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