Effect of intraumbilical vein oxytocin injection on third stage of labor

Nankali, Anisodowleh; Keshavarzi, Farahnaz; Fakheri, Taravat; Zare, Shamsy; Rezaei, Mansour; Daeichin, Sara

doi:10.1016/j.tjog.2013.01.010

Cited by 12 publications

(13 citation statements)

References 10 publications

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“…In present study, it was also shown that women in the study group had significantly shorter duration of the third stage when compared with women in the control group. This is in accordance with the study of Nankali et al, (2013). In their study, they aimed to determine whether intraumbilical vein oxytocin injection reduces the need for manual removal of placenta and shortens the third stage of labor, in comparison with placebo.…”

Section: Discussionsupporting

confidence: 68%

“…In their study, they aimed to determine whether intraumbilical vein oxytocin injection reduces the need for manual removal of placenta and shortens the third stage of labor, in comparison with placebo. In the study of Nankali et al, (2013) randomized clinical trial, 178 women with singleton pregnancy and normal delivery were studied in 1 year. Immediately after fetus delivery, oxytocin infusion (20 IU/L) was started in both groups.…”

Section: Discussionmentioning

confidence: 99%

“…The duration of the third stage of labor is 5-15 min; however, in 2-5% of cases, placenta retention occurs and if immediate treatment is not undertaken, these women are at risk of hemorrhage (Nankali et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

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Study of the Effect of Intraumbilical Vein Oxytocin Injection on Third Stage of Labor

Zaher

2018

Al-Azhar Journal of Pharmaceutical Sciences

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Background: The principal management of the third stage of labor is aimed at reducing the time of delivery of the placenta, thereby minimizing serious adverse effects such as blood loss and retained placenta. Umbilical vein oxytocin injection directs treatment to the placental bed and uterine wall, resulting in earlier uterine contraction and placental separation Aim of study: The present study aimed to evaluate the effect of intraumbilical vein oxytocin on reducing the duration of the third stage of labor and the need for manual delivery of placenta, in comparison with normal saline administration. Patients and Methods: The present study recruited 300 hundred women indicated for normal labor. They were equally and randomly assigned into one of two groups: GI (the study group) which had intraumbilical oxytocin and GII (control group) which had normal saline infusion. Results: Comparison between the studied groups regarding the demographic data didn't reveal statistically significant differences. In addition, there were no statistically significant differences between the studied groups regarding the obstetrical data. Furthermore, no statistically significant differences were found between the studied groups regarding the preoperative Hb levels. There was a statistically significant higher blood loss in the control group when compared with the study group. In addition, the study group had significantly higher postoperative Hb when compared with controls. They were also found to have less Hb difference when compared with controls. It was also shown that that women in the study group had significantly shorter duration of the third stage when compared with women in the control group. Regarding the reported complications in the studied groups, we showed no statistically significant differences between the studied groups regarding the reported complications. Conclusions: Intraumbilical oxytocin resulted in shorter duration of the third stage of labor. It also resulted in less blood loss and less hemoglobin concentration reduction.

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Section: Discussionsupporting

confidence: 68%

Section: Discussionmentioning

confidence: 99%

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Study of the Effect of Intraumbilical Vein Oxytocin Injection on Third Stage of Labor

Zaher

2018

Al-Azhar Journal of Pharmaceutical Sciences

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“…Placental expulsion depends its separation from uterine wall, capillary hemorrhage, contractility of the uterine muscle, maternal effort, and gravity effect on the placenta [12]. Placenta delivery is generally completed within 15 minutes following the fetus delivery in 90% of parturient [10,13]. Two distinct methods are usually used to manage the 3 rd stage of labor.…”

Section: Introductionmentioning

confidence: 99%

Effect of Placental Cord Drainage on the Third Stage of Labour Progress and Incidence of Postpartum Hemorrhage: Randomized Controlled Clinical Trial

Elgzar¹,

Ibrahim²,

Elkhateeb³

2020

SARJNHC

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Background: Postpartum hemorrhage (PPH) is accountable for around 25% of maternal mortality in the developing countries. Management of 3 rd stage of labour is the cornerstone in PPH prevention. The effect of Placenta Cord Drainage (PCD) on the 3 rd progress and PPH prevention is still controversy. Aim of the study: This study aims to investigate the effect of placental drainage on the third stage of labour progress and incidence of postpartum hemorrhage. Research design: randomized controlled clinical trial. Setting: This study is conducted at normal labour unit at Damanhour educational institution affiliated to ministry of health at Elbehira governorate/Egypt. Sampling: A purposive sample of 120 women undergoing normal easy vaginal delivery. Tools: two tools were used for data collection. Tool I: sociodemographic characteristics and obstetric history interview schedule. Tool II: Labour assessment sheet it consists of three main parts. Part I: Summary of the first and second stage of labor. Part II: third stage assessment sheet. Part III: 3. Early postpartum assessment sheet. Results: The present study results shows no statistical significant differences between PCD and control group regarding vital signs during the 3rd stage, uterus condition after placenta delivery, type, dose and route of uterotonic drugs given during 3rd stage. On the contrary, a statistical significant reduction in the time elapsed until appearance of placenta separation signs (3.5583±0.83915), 3rd stage duration(5.1417±1.03138), amount of blood loss during 3rd stage (195.45±13.994), placenta weight (580.333±64.97631) and incidence of retained placenta ((0%) in the PCD group than control. In the early postpartum assessment, the mean pulse (88.2.7667±3.11022) is higher among control group compared to PCD (83.4667±2.78292) group. Control group needs higher dose of uterotonic (8.6780±2.62902) drugs than PCD (5.0566±1.41985) group. In addition, maternal hemoglobin (9.5234±0.6087) is slightly higher in PCD group compared to control (8.458±0.873). Conclusion: PCD is safe, effective noninvasive intervention that may help in improving 3 rd stage progress. Recommendation: PCD should be added to third stage of labour intervention protocol.

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“…Placental expulsion depends on the separation of the placenta from the uterine wall, capillary hemorrhage, uterine muscle contractile ability after placental separation, maternal effort, and gravity of the placenta (4,5). Separation of the placenta from the uterine wall is usually completed within 15 minutes in 90% of women after a fetal delivery (2,6). Prolongation of the TSL increases the development of PPH, which is responsible for one quarter of maternal deaths globally, one third of all pregnancy-related deaths in Africa and Asia, and approximately 140.000 deaths annually (7,8).…”

Section: Introductionmentioning

confidence: 99%

Placental Blood Drainage Shortens Duration of the Third Stage of Labor in Women Slowly Administered 20 IU Oxytocin

Kaba

Üstün

Eyı

et al. 2017

Gynecol Obstet Reprod Med

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OBJECTIVE: Prolongation of the third stage of labor may cause serious postpartum complications. Thus, timely expulsion of the placenta is essential for preventing complications of the third stage of labor. We conducted a prospective cohort study to determine the effect of placental cord drainage on the duration of the TSL in women administered intravenous oxytocin during this stage. STUDY DESIGN:This was a prospective cohort study in which 112 low risk pregnant women were allocated to the study. There were 53 women in the placental cord drainage group, and 59 women in the cord clamping group without drainage. Immediately after fetal delivery, intravenous infusion of 20 IU oxytocin in 500 mL Ringers' Lactate was started and infused within 2 hours in women in both groups. Outcome measures were the third stage duration and hemoglobin differences between admission and the postpartum sixth hour. RESULTS:There were no significant differences between the two groups with regard to duration of stages 1 and 2 of labor, hemoglobin level on admission, and at the postpartum sixth hour, and hemoglobin differences between admission and the postpartum sixth hour. The median third stage duration in the study group was 3.40 (range: 0.35-16.20) minutes, and 5.10 (range: 2.30-11.00) minutes in the control group. This difference between the groups was statistically significant (p<0.01). CONCLUSION:Placental cord drainage reduces the third stage duration following vaginal deliveries in patients receiving intravenous oxytocin. Placental cord drainage is simple, does not require additional cost, and is applicable for every delivery.Keywords: Third stage of labor, Active management of the third stage, Placental cord drainage,

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Effect of intraumbilical vein oxytocin injection on third stage of labor

Abstract: It was concluded that intraumbilical vein administration of 10 IU (1 mL) oxytocin immediately after fetus delivery was clinically effective in shortening the third stage of labor.

Cited by 12 publications

References 10 publications

Study of the Effect of Intraumbilical Vein Oxytocin Injection on Third Stage of Labor

Study of the Effect of Intraumbilical Vein Oxytocin Injection on Third Stage of Labor

Effect of Placental Cord Drainage on the Third Stage of Labour Progress and Incidence of Postpartum Hemorrhage: Randomized Controlled Clinical Trial

Placental Blood Drainage Shortens Duration of the Third Stage of Labor in Women Slowly Administered 20 IU Oxytocin

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