Effect of intranasal insulin on osteocalcin levels and postoperative delirium in elderly patients undergoing joint replacement
Yang Mi,
Zhou Lei,
Long Ge
et al.
Abstract:BackgroundRecently, intranasal insulin has shown great promise in preventing perioperative neurocognitive disorders through ameliorating insulin sensitivity and cognitive function. Whether osteocalcin, as a bone-derived hormone that can directly regulate insulin sensitivity and cognitive function, is linked to the mechanism of intranasal insulin remains ill-defined.AimsTo explore the effect of intranasal insulin on osteocalcin levels and the incidence and severity of postoperative delirium (POD) in elderly pat… Show more
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