Effect of intramuscular administration of dexamethasone on the duration of labor

Kashanian, Maryam; Dadkhah, Farideh; Mokhtari, Fattaneh

doi:10.1016/j.ijgo.2008.04.009

Cited by 12 publications

(5 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study, there were no significant statistical differences between the two studied groups as regards fetal heart rate. This was in agreement with Kashanian et al (14) who found that there were no significant differences in fetal heart rate. It seems clear that corticosteroids administered intramuscularly could facilitate the induction and the delivery process in extended pregnancy.…”

Section: Discussionsupporting

confidence: 93%

“…In this study, the duration of second stage in dexamethasone group was shorter than in the control group. Moreover in agreement with Kashanian et al [14] who carried out a double-blind, randomized, controlled trial upon 122 nulliparous with a full-term pregnancy and a Bishop score of 7 or greater and randomly assigned to receive a single 8 mg dose of dexamethasone or placebo 6 hours before initiation of labor induction, the interval between initiation of labor induction and beginning of active phase of labor was shorter in the dexamethasone group than in the control group (3. 09± 1.…”

Section: Discussionsupporting

confidence: 59%

See 1 more Smart Citation

Effect of intramuscular administration of dexamethasone on the duration of labor induction

Elmaraghy

Refaie

Labib

et al. 2018

Evidence Based Women's Health Journal

View full text Add to dashboard Cite

Introduction: induction of labor is a common obstetric procedure which is performed for a variety of medical and nonmedical indications. If the cervix is unfavorable, prior ripening of the cervix makes induction of labor easier and more successful. There are different methods for ripening of the cervix and making it ready for induction. These methods included medical methods such as the administration of prostaglandins and mechanical methods such as extra amniotic saline infusion, traction on the cervix with Foley catheter and laminaria. Aim: The aim of the study is to evaluate the efficacy of intramuscular dexamethazone injection prior to induction in improving progression and duration of labour phases. Subjects and Methods: This study started with 100 Nulliparous Pregnant women who were conducted at the labor wards of Ain-Shams Maternity Hospital. The studied subjects were randomized into two groups ; dexamethasone group (group A) including 50 Nulliparous women (N=50) and control group (group B) including 50 Nulliparous woman (N=50). Results: In this study, the duration of active and second stages decreased without changing the mode of delivery. The study showed no significant statistical differences between the two studied groups regarding fetal heart rate. The duration of second stage in dexamethasone group was shorter than in the control group. Dexamethasone intramuscularly prior to induction significantly shortens duration of normal labor in normal parturient with minimal complications. Conclusion: An intramuscular injection of dexamethasone before labor induction shortens the duration of labor induction by decreasing the interval between the initiation of induction and the beginning of the active phase, duration of active phase and duration of second stage of labor with no observed maternal or neonatal complications. Recommendation: Further research with more patients undertaken for the assessment of the effects of the corticosteroids on the duration of labor on the patients with unfavorable cervix as well as maternal and perinatal morbidity and mortality rate.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 59%

Effect of intramuscular administration of dexamethasone on the duration of labor induction

Elmaraghy

Refaie

Labib

et al. 2018

Evidence Based Women's Health Journal

View full text Add to dashboard Cite

show abstract

“…11 Abstracts from electronic search excluded because -7 RCTs on repeated doses ANS (43)(44)(45)(46)(47)(48)(49) -2 RCTs including only full term pregnancies (50,51) -2 RCTs giving ANS without imminent delivery (52,53) Figure 1 Flow of inclusion randomized controlled trials in different phases of search. 1,37,38,[43][44][45][46][47][48][49][50][51][52][53] ANS, antenatal steroids; GA, gestational age; RCT, randomized controlled trial. similar GA and birth weight, whereas two trials included patients with considerable lower GA and birth weight (Table 2).…”

Section: Study Characteristicsmentioning

confidence: 99%

Effects of Antenatal Corticosteroids Given Prior to 26 Weeks' Gestation: A Systematic Review of Randomized Controlled Trials

et al. 2010

View full text Add to dashboard Cite

Although it is generally accepted that antenatal corticosteroids reduce neonatal complications after preterm labor, it is unclear at what gestational age this effect starts to occur. We conducted a systematic review of the literature to determine the effects of antenatal corticosteroids given to women at risk of preterm birth <26 weeks' gestation. Two reviewers independently searched electronic databases and the Cochrane Library for randomized controlled trials including women at imminent birth at a gestational age <26 weeks. Nine randomized trials were included. Meta-analyses and meta-regression of trials including participants with a lower gestational age revealed no significant reduction of neonatal mortality and morbidity in the corticosteroid group as compared with nonintervention, in contrast to clear evidence of beneficial effects in trials including women given corticosteroids at a later gestational age. A gestational age-dependent effect of antenatal corticosteroids on neonatal outcomes with lesser treatment benefits in patients <26 weeks' gestational age appears to exist. There is no evidence from randomized controlled trials to support or refute the recommendation of administrating antenatal corticosteroids to women at risk of preterm birth <26 weeks' gestation.

show abstract

“…As regards the effect of intramascular administration of dexamethasone on the duration of labor, our findings are in agreement with those of Kashanian et al, who reported that IM dexamethasone (8mg) injection 6 hours before IOL significantly shortens both the time interval between IOL initiation and the active phase of labour commencement (3.09 ± 1.5 hours vs. 4.21 ± 1.8 hours in control group; p=0.001) & the duration of the 2 nd stage (22.23 ± 16.09 minutes vs. 29.01 ± 15.32 minutes; p=0.0014) [13] . Similarly Ziaei et al, declared that using dexamethasone injections results in a notable decrease in the duration of the latent phase of labour (1.7 ± 1.5 hours vs. 4 ± 1.7 hours in control group; p=0.001), however, they failed to demonstrate any impact of dexamethasone on the duration of the second and third stages of labour [14] .…”

Section: Discussionmentioning

confidence: 98%

The Effect of Intramuscular Administration of Dexamethasone Alone or in Combination with Hyoscine Butylbromide in Shortening the duration of Induced Labor in Primigravidas

Helal¹,

Zaki

2018

The Medical Journal of Cairo University

View full text Add to dashboard Cite

Background: Induction of labour is common in clinical practice and is usually troublesome in primigravidas. Obestatricians are always in search of the best method of induction to ensure the best maternal and fetal outcome.3 rd stage (6.3 ± 1.7 and 7.5 ± 1.9 vs. 10.0 ± 2.8 minutes) respectively when compared to the control group ( p-value <0.001 for all). No statistical significant differences were noticed in neonatal Apgar score at 1 and 5 minutes between the three groups.

show abstract

Effect of intramuscular administration of dexamethasone on the duration of labor

Abstract: The administration of dexamethasone was found to shorten labor duration.

Cited by 12 publications

References 25 publications

Effect of intramuscular administration of dexamethasone on the duration of labor induction

Effect of intramuscular administration of dexamethasone on the duration of labor induction

Effects of Antenatal Corticosteroids Given Prior to 26 Weeks' Gestation: A Systematic Review of Randomized Controlled Trials

The Effect of Intramuscular Administration of Dexamethasone Alone or in Combination with Hyoscine Butylbromide in Shortening the duration of Induced Labor in Primigravidas

Contact Info

Product

Resources

About