Effect of intracranial venous collaterals on neurological outcomes in cerebral venous thrombosis

Zhao, Yanying; Su, Xudong; Zengpin, Liu; Zhou, Cunhe; Yu, Jianxing; Wang, Xiaopeng; Zhang, Lixia; Zhao-xia, Shi; Liu, Lin; Lu, Honglin; Zhao, Pandi; Li, Zhongzhong; Bu, Kailin; Guo, Li; Liu, Xiaoyun

doi:10.1016/j.jocn.2022.06.009

Cited by 7 publications

(9 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…As venous collaterals were not assessed in previous studies, the available data regarding their prevalence in patients with CVT is limited. Our study revealed the prevalence of venous collaterals in this population to be 25.3%, which was low compared to previous reports ranging between 66% and 89% [ 1 , 3 , 4 ].…”

Section: Discussioncontrasting

confidence: 86%

“…Therefore, the prevalence of venous collaterals might have been overestimated by Sheth et al [ 1 ]. In addition, Zhao et al [ 4 ] categorized venous collaterals into one of two groups based on the number of well-visualized collateral pathways: poor collaterals (0–1 well-visualized pathway) and good collaterals (2 or more well-visualized pathways). The number of patients with poor collaterals might have been overestimated by Zhao et al [ 4 ], as patients without any visualized venous collaterals were included in this group.…”

Section: Discussionmentioning

confidence: 99%

“…In terms of the clinical outcome prediction, these studies showed discordant results; either positive, negative or undetermined effect on the clinical outcome [ 1 – 3 ]. In the viewpoint of radiological outcome, a single study revealed the prediction of early recanalization [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Factors associated with venous collaterals in patients with cerebral venous thrombosis

Petchprom,

Sanghan,

Khumthong

et al. 2024

PLoS ONE

View full text Add to dashboard Cite

Objectives To identify the factors associated with venous collaterals in Thai patients with cerebral venous thrombosis. Materials and methods This retrospective 20-year cohort study enrolled patients diagnosed with cerebral venous thrombosis between January 2002 and December 2022. Data was collected from the electronic medical record, and venous collaterals were independently reviewed by two neuroradiologists using the Qureshi classification. Patients with and without venous collaterals were compared. Significant factors (P<0.05) in the univariate analysis were recruited into the multivariate logistic regression analysis to determine independently associated factors. Results Among 79 patients with cerebral venous thrombosis, the prevalence of venous collaterals at the initial neuroimaging was 25.3%. In the univariate analysis, patients with cerebral venous thrombosis and venous collaterals were significantly younger (37.0±13.9 years vs. 44.9±17.4 years, P = 0.048), more often had occlusion in the superior sagittal sinus (80.0% vs. 54.2%, P = 0.041), and were associated with hormonal exposure (35.0% vs. 6.8%, P = 0.002). Multivariate logistic regression analysis revealed occlusion in the superior sagittal sinus (adjusted odds ratio [aOR] 3.581; 95% confidence interval [95% CI] 1.941–13.626; P = 0.044) and hormonal exposure (aOR 7.276, 95% CI 1.606–32.966, P = 0.010) as independent factors associated with venous collaterals in cerebral venous thrombosis. Conclusions In this cohort, the prevalence of venous collaterals was 25.3%. Occlusion in the superior sagittal sinus and hormonal exposure were independently associated with venous collaterals in patients with cerebral venous thrombosis.

show abstract

Section: Discussioncontrasting

confidence: 86%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Factors associated with venous collaterals in patients with cerebral venous thrombosis

Petchprom,

Sanghan,

Khumthong

et al. 2024

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…In real-world practice, clinicians often encounter patients with TOB who show delayed perfusion proximal to the TOB in the territories of the anterior or posterior inferior cerebellar artery (AICA or PICA) before MT. We hypothesized that unlike in the anterior circulation LVO, such as middle cerebral artery occlusion, which has an alternative flow path including the anterior cerebral artery, the blood flow stasis, and congestion proximal to the occlusion site, may more easily occur in TOB as it is an occlusion of the single path end-artery ( 10 , 11 ). Therefore, we investigated that initial perfusion delay proximal to TOB at the low cerebellum would be associated with the outcome in patients treated with MT.…”

Section: Introductionmentioning

confidence: 99%

Delayed low cerebellar perfusion status is associated with poor outcomes in top-of-basilar occlusion treated with thrombectomy

et al. 2023

View full text Add to dashboard Cite

Background and purposeTop-of-basilar artery occlusion (TOB) is one of the most devastating strokes despite successful mechanical thrombectomy (MT). We aimed to investigate the impact of initial low cerebellum perfusion delay on the outcomes of TOB treated with MT.MethodsWe included patients who underwent MT for TOB. Clinical and peri-procedural variables were obtained. Perfusion delay in the low cerebellum was defined as (1) time-to-maximum (Tmax) >10 s lesions or (2) relative time-to-peak (rTTP) map >9.5 s with a diameter of ≥6 mm in the low cerebellum. The good functional outcome was defined as the achievement of a modified Rankin Scale score of 0–3 at 3 months after stroke.ResultsAmong the 42 included patients, 24 (57.1%) patients showed perfusion delay in the low cerebellum. The admission National Institutes of Health Stroke Scale (NIHSS) score was significantly higher in those with perfusion delay [17 (12–24) vs. 8 (6–15), P = 0.002]. Accordingly, the proportion of good functional outcomes was lower in those with perfusion delay than in those without [5 (20.8%) vs. 13 (72.2%), P = 0.003]. From the multivariable analysis, the admission NIHSS score [odds ratio (OR) = 0.86, 95% confidence intervals (CIs) = 0.75–0.98, P = 0.021] and low cerebellum perfusion delay (OR = 0.18, 95% Cis = 0.04–0.86, P = 0.031) were independently associated with the 3-month functional outcomes.ConclusionWe found that initial perfusion delay proximal to TOB in the low cerebellum might be a predictor for poor functional outcomes in TOB treated with MT.

show abstract

“…These characteristics resulted in the fact that more focus has been placed for years on the cerebral artery instead of the cerebral vein ( 11 ). However, due to the rapid improvement of medical diagnosis and treatment and continuous development of imaging technology, the role of the morphological characteristics of cerebral veins has gained increasing emphasis in the regulation of cerebral blood circulation and the occurrence and development of cerebral venous diseases ( 12 – 15 ).…”

Section: Introductionmentioning

confidence: 99%

Magnetic resonance analysis of deep cerebral venous vasospasm after subarachnoid hemorrhage in rabbits

Zhang

Fang

Zhu³

et al. 2022

Front. Cardiovasc. Med.

View full text Add to dashboard Cite

ObjectiveArterial spasm is proved to be an inducer of cerebral ischemia and cerebral infarction, while when a venous spasm occurs, cerebral edema is seen to be caused by a disturbance in cerebral blood flow. However, it is unclear and unproven whether venous spasm occurs after subarachnoid hemorrhage (SAH). To provide the theoretical basis for treating cerebral vasospasm after SAH, magnetic resonance imaging (MRI) was employed to observe the changes in the diameter of deep cerebral veins in rabbits after SAH.MethodsFourteen New Zealand rabbits were randomly divided into the SAH group (n = 10) and the normal saline group (NS group, n = 4). Specifically, the SAH models were established by the ultrasound-guided double injections of blood into cisterna magna. Moreover, the MRI was performed to observe the changes in the diameter of deep cerebral veins (internal cerebral vein, basilar vein, and great cerebral vein) and basilar artery before modeling (0 d) and 1, 3, 5, 7, 9, and 11 d after modeling.ResultsIn the SAH group, the diameter of the basilar artery showed no evident change on the 1st d. However, it became narrower obviously on the 3rd d and 5th d, and the stenosis degree was more than 30%. The diameter gradually relieved from 7th to 9th d, and finally returned to normal on the 11th d. Moreover, the diameter of the internal cerebral vein significantly narrowed on the 1st d, the stenosis degree of which was 19%; the stenosis then relieved slightly on the 3rd d (13%), reached the peak (34%) on the 5th d, and gradually relieved from 7th d to 11th d. Moreover, the stenosis degree of the basilar vein was 18% on the 1st d, 24% on the 3rd d, and reached the peak (34%) on the 5th d.ConclusionAfter SAH in rabbits, the cerebral vasospasm was seen to occur in the basilar artery, and likewise, spasmodic changes took place in the deep cerebral vein. Furthermore, the time regularity of spasmodic changes between the cerebral vein and basilar artery was of significant difference, indicating that the venous vasospasm resulted in active contraction.

show abstract

Effect of intracranial venous collaterals on neurological outcomes in cerebral venous thrombosis

Cited by 7 publications

References 21 publications

Factors associated with venous collaterals in patients with cerebral venous thrombosis

Factors associated with venous collaterals in patients with cerebral venous thrombosis

Delayed low cerebellar perfusion status is associated with poor outcomes in top-of-basilar occlusion treated with thrombectomy

Magnetic resonance analysis of deep cerebral venous vasospasm after subarachnoid hemorrhage in rabbits

Contact Info

Product

Resources

About